Oncogenic Herpesvirus KSHV Hijacks BMP-Smad1-Id Signaling to Promote Tumorigenesis

Viral Cyclin promotes KSHV-induced cellular transformation and tumorigenesis by overriding contact inhibition

(2014) Tiffany Jones et al.   CELL CYCLE

Kaposi's Sarcoma-Associated Herpesvirus-Encoded LANA Interacts with Host KAP1 To Facilitate Establishment of Viral Latency

(2014) R. Sun et al.   JOURNAL OF VIROLOGY

AMPK Activation by Oncogenesis Is Required to Maintain Cancer Cell Proliferation in Astrocytic Tumors

(2013) M. Rios et al.   CANCER RESEARCH

KSHV MicroRNAs Mediate Cellular Transformation and Tumorigenesis by Redundantly Targeting Cell Growth and Survival Pathways

(2013) Rosalie Moody et al.   PLoS Pathogens

The CRTC1-NEDD9 Signaling Axis Mediates Lung Cancer Progression Caused by LKB1 Loss

(2012) Y. Feng et al.   CANCER RESEARCH

Direct and efficient cellular transformation of primary rat mesenchymal precursor cells by KSHV

(2012) Tiffany Jones et al.   JOURNAL OF CLINICAL INVESTIGATION

A Kaposi's Sarcoma-Associated Herpesvirus MicroRNA and Its Variants Target the Transforming Growth Factor   Pathway To Promote Cell Survival

(2012) X. Lei et al.   JOURNAL OF VIROLOGY

The specificities of small molecule inhibitors of the TGFß and BMP pathways

(2011) Janis Vogt et al.   CELLULAR SIGNALLING

The latency-associated nuclear antigen, a multifunctional protein central to Kaposi’s sarcoma-associated herpesvirus latency

(2011) Mary E Ballestas et al.   Future Microbiology

Molecular Mechanism of the Negative Regulation of Smad1/5 Protein by Carboxyl Terminus of Hsc70-interacting Protein (CHIP)

(2011) Le Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Kaposi's Sarcoma-Associated Herpesvirus-Encoded MicroRNA miR-K12-11 Attenuates Transforming Growth Factor Beta Signaling through Suppression of SMAD5

(2011) Y. Liu et al.   JOURNAL OF VIROLOGY

Kaposi's Sarcoma-Associated Herpesvirus-Encoded Latency-Associated Nuclear Antigen Reduces Interleukin-8 Expression in Endothelial Cells and Impairs Neutrophil Chemotaxis by Degrading Nuclear p65

(2011) X. Li et al.   JOURNAL OF VIROLOGY

Bone morphogenetic proteins in breast cancer: dual role in tumourigenesis?

(2010) Emma-Leena Alarmo et al.   ENDOCRINE-RELATED CANCER

WSS25 Inhibits Growth of Xenografted Hepatocellular Cancer Cells in Nude Mice by Disrupting Angiogenesis via Blocking Bone Morphogenetic Protein (BMP)/Smad/Id1 Signaling

(2010) Hong Qiu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a Lysosomal Pathway Regulating Degradation of the Bone Morphogenetic Protein Receptor Type II

(2010) Hannah J. Durrington et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

KSHV and the pathogenesis of Kaposi sarcoma: listening to human biology and medicine

(2010) Don Ganem   JOURNAL OF CLINICAL INVESTIGATION

Human herpesvirus 8 viral FLICE-inhibitory protein retards cell proliferation via downregulation of Id2 and Id3 expression

(2010) Yi-Fen Wang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Upregulation of Id1 by Epstein-Barr Virus-encoded LMP1 confers resistance to TGFβ-mediated growth inhibition

(2010) Angela KF Lo et al.   Molecular Cancer

AMP-activated protein kinase-dependent and -independent mechanisms underlying in vitro antiglioma action of compound C

(2009) Ljubica Vucicevic et al.   BIOCHEMICAL PHARMACOLOGY

Biology of BMP signalling and cancer

(2009) Moisés Blanco Calvo et al.   Clinical & Translational Oncology

Bone morphogenetic protein receptors and signal transduction

(2009) K. Miyazono et al.   JOURNAL OF BIOCHEMISTRY

KSHV LANA inhibits TGF-  signaling through epigenetic silencing of the TGF-  type II receptor

(2008) D. L. Di Bartolo et al.   BLOOD

Prolyl 4-hydroxylation regulates Argonaute 2 stability

(2008) Hank H. Qi et al.   NATURE

Kaposi’s sarcoma-associated herpesvirus RTA activates the processivity factor ORF59 through interaction with RBP-Jκ and a cis-acting RTA responsive element

(2008) Yunhua Liu et al.   VIROLOGY