Early Mucosal Sensing of SIV Infection by Paneth Cells Induces IL-1β Production and Initiates Gut Epithelial Disruption

Mechanism of IL-1 -Induced Increase in Intestinal Epithelial Tight Junction Permeability

(2014) R. Al-Sadi et al.   JOURNAL OF IMMUNOLOGY

Enhanced Innate Antiviral Gene Expression, IFN- , and Cytolytic Responses Are Predictive of Mucosal Immune Recovery during Simian Immunodeficiency Virus Infection

(2014) D. Verhoeven et al.   JOURNAL OF IMMUNOLOGY

Intestinal Epithelial Barrier Disruption through Altered Mucosal MicroRNA Expression in Human Immunodeficiency Virus and Simian Immunodeficiency Virus Infections

(2014) C. A. Gaulke et al.   JOURNAL OF VIROLOGY

Alterations in the Gut Microbiota Associated with HIV-1 Infection

(2013) Catherine A. Lozupone et al.   Cell Host & Microbe

NLRP3 and IL-1βin macrophages as critical regulators of metabolic diseases

(2013) A. F. McGettrick et al.   DIABETES OBESITY & METABOLISM

Mucosal innate immune cells regulate both gut homeostasis and intestinal inflammation

(2013) Yosuke Kurashima et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Chronic HIV Infection Enhances the Responsiveness of Antigen Presenting Cells to Commensal Lactobacillus

(2013) Lauren H. Nagy et al.   PLoS One

HIV Infection is associated with compositional and functional shifts in the rectal mucosal microbiota

(2013) Ian H McHardy et al.   Microbiome

HIV Type 1 Infection Up-Regulates TLR2 and TLR4 Expression and Function in Vivo and in Vitro

(2012) Juan C. Hernández et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Regulation of intestinal epithelial permeability by tight junctions

(2012) Takuya Suzuki   CELLULAR AND MOLECULAR LIFE SCIENCES

Constitutive Gene Expression in Monocytes from Chronic HIV-1 Infection Overlaps with Acute Toll-Like Receptor Induced Monocyte Activation Profiles

(2012) Bethsebah Gekonge et al.   PLoS One

Acute Gastrointestinal Infection Induces Long-Lived Microbiota-Specific T Cell Responses

(2012) T. W. Hand et al.   SCIENCE

HIV-1 induces NALP3-inflammasome expression and interleukin-1β secretion in dendritic cells from healthy individuals but not from HIV-positive patients

(2011) Alessandra Pontillo et al.   AIDS

Pathogenic Mechanisms of HIV Disease

(2011) Susan Moir et al.   Annual Review of Pathology-Mechanisms of Disease

Specific prebiotics modulate gut microbiota and immune activation in HAART-naive HIV-infected adults: results of the “COPA” pilot randomized trial

(2011) A Gori et al.   Mucosal Immunology

Control of TH17 cells occurs in the small intestine

(2011) Enric Esplugues et al.   NATURE

Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut

(2011) Natalia Shulzhenko et al.   NATURE MEDICINE

Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis

(2011) Charles L. Bevins et al.   NATURE REVIEWS MICROBIOLOGY

IL-1β-Induced Increase in Intestinal Epithelial Tight Junction Permeability Is Mediated by MEKK-1 Activation of Canonical NF-κB Pathway

(2010) Rana Al-Sadi et al.   AMERICAN JOURNAL OF PATHOLOGY

Regulation of human epithelial tight junction proteins by Lactobacillus plantarum in vivo and protective effects on the epithelial barrier

(2010) Jurgen Karczewski et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Lactobacillus plantarum MB452 enhances the function of the intestinal barrier by increasing the expression levels of genes involved in tight junction formation

(2010) Rachel C Anderson et al.   BMC MICROBIOLOGY

Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD)

(2010) R. DUCHMANN et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Persistence of Gut Mucosal Innate Immune Defenses by Enteric  -Defensin Expression in the Simian Immunodeficiency Virus Model of AIDS

(2010) M. M. Zaragoza et al.   JOURNAL OF IMMUNOLOGY

Lactobacillus plantarum surface layer adhesive protein protects intestinal epithelial cells against tight junction injury induced by enteropathogenic Escherichia coli

(2010) Zhihua Liu et al.   MOLECULAR BIOLOGY REPORTS

Th17 cells, HIV and the gut mucosal barrier

(2010) Satya Dandekar et al.   Current Opinion in HIV and AIDS

Damaged Intestinal Epithelial Integrity Linked to Microbial Translocation in Pathogenic Simian Immunodeficiency Virus Infections

(2010) Jacob D. Estes et al.   PLoS Pathogens

Exposure to HIV-1 Directly Impairs Mucosal Epithelial Barrier Integrity Allowing Microbial Translocation

(2010) Aisha Nazli et al.   PLoS Pathogens

Bacteria-free solution derived from lactobacillus plantarum inhibits multiple NF-kappaB pathways and inhibits proteasome function

(2009) Elaine O. Petrof et al.   INFLAMMATORY BOWEL DISEASES

Differential NF- B pathways induction by Lactobacillus plantarum in the duodenum of healthy humans correlating with immune tolerance

(2009) P. van Baarlen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Primary infection with simian immunodeficiency virus: plasmacytoid dendritic cell homing to lymph nodes, type I interferon, and immune suppression

(2008) B. Malleret et al.   BLOOD

Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections

(2008) J. M. Brenchley et al.   BLOOD

Simian Immunodeficiency Virus–Induced Intestinal Cell Apoptosis Is the Underlying Mechanism of the Regenerative Enteropathy of Early Infection

(2008) Qingsheng Li et al.   JOURNAL OF INFECTIOUS DISEASES

Effective CD4+ T-cell restoration in gut-associated lymphoid tissue of HIV-infected patients is associated with enhanced Th17 cells and polyfunctional HIV-specific T-cell responses

(2008) M Macal et al.   Mucosal Immunology

Simian immunodeficiency virus–induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut

(2008) Manuela Raffatellu et al.   NATURE MEDICINE