Cathepsin-L Can Resist Lysis by Human Serum in Trypanosoma brucei brucei

Inhibition of Rhodesain as a Novel Therapeutic Modality for Human African Trypanosomiasis

(2013) Roberta Ettari et al.   JOURNAL OF MEDICINAL CHEMISTRY

Mechanism of Trypanosoma brucei gambiense resistance to human serum

(2013) Pierrick Uzureau et al.   NATURE

A Single Amino Acid Substitution in the Group 1 Trypanosoma brucei gambiense Haptoglobin-Hemoglobin Receptor Abolishes TLF-1 Binding

(2013) E. DeJesus et al.   PLoS Pathogens

The TgsGP Gene Is Essential for Resistance to Human Serum in Trypanosoma brucei gambiense

(2013) Paul Capewell et al.   PLoS Pathogens

Trypanosoma brucei: Chemical evidence that cathepsin L is essential for survival and a relevant drug target

(2012) Dietmar Steverding et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Natively Inhibited Trypanosoma brucei Cathepsin B Structure Determined by Using an X-ray Laser

(2012) L. Redecke et al.   SCIENCE

Haptoglobin-hemoglobin receptor independent killing of African trypanosomes by human serum and trypanosome lytic factors

(2012) Whitney Bullard et al.   Virulence

Trypanosoma brucei gambiense Group 1 Is Distinguished by a Unique Amino Acid Substitution in the HpHb Receptor Implicated in Human Serum Resistance

(2012) Rebecca E. Symula et al.   PLoS Neglected Tropical Diseases

State of the Art in African Trypanosome Drug Discovery

(2011) Robert T. Jacobs et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Endosomal Localization of the Serum Resistance-Associated Protein in African Trypanosomes Confers Human Infectivity

(2011) Natalie A. Stephens et al.   EUKARYOTIC CELL

High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome

(2011) S. Alsford et al.   GENOME RESEARCH

Differences between Trypanosoma brucei gambiense Groups 1 and 2 in Their Resistance to Killing by Trypanolytic Factor 1

(2011) Paul Capewell et al.   PLoS Neglected Tropical Diseases

The Human African Trypanosomiasis Control and Surveillance Programme of the World Health Organization 2000–2009: The Way Forward

(2011) Pere P. Simarro et al.   PLoS Neglected Tropical Diseases

Conserved sequence of the TgsGP gene in Group 1 Trypanosoma brucei gambiense

(2010) Wendy Gibson et al.   INFECTION GENETICS AND EVOLUTION

Selection of reference genes for mRNA quantification in Trypanosoma brucei

(2010) Martin Brenndörfer et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Genome-wide RNAi screens in African trypanosomes identify the nifurtimox activator NTR and the eflornithine transporter AAT6

(2010) Nicola Baker et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

The trypanolytic factor of human serum: many ways to enter the parasite, a single way to kill

(2010) Benoit Vanhollebeke et al.   MOLECULAR MICROBIOLOGY

Mechanism of Trypanosoma brucei gambiense (group 1) resistance to human trypanosome lytic factor

(2010) R. Kieft et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Genome Sequence of Trypanosoma brucei gambiense, Causative Agent of Chronic Human African Trypanosomiasis

(2010) Andrew P. Jackson et al.   PLoS Neglected Tropical Diseases

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Hydrodynamic gene delivery of baboon trypanosome lytic factor eliminates both animal and human-infective African trypanosomes

(2009) R. Thomson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

A Parasite Cysteine Protease Is Key to Host Protein Degradation and Iron Acquisition

(2008) Theresa C. O'Brien et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Single-locus targeting constructs for reliable regulated RNAi and transgene expression in Trypanosoma brucei

(2008) Sam Alsford et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

The LAMP-like protein p67 plays an essential role in the lysosome of African trypanosomes

(2008) Ronald F. Peck et al.   MOLECULAR MICROBIOLOGY

A Haptoglobin-Hemoglobin Receptor Conveys Innate Immunity to Trypanosoma brucei in Humans

(2008) B. Vanhollebeke et al.   SCIENCE