HTLV-1 Tax-Mediated Inhibition of FOXO3a Activity Is Critical for the Persistence of Terminally Differentiated CD4+ T Cells

Transcription Factor FOXO3a Mediates Apoptosis in HIV-1-Infected Macrophages

(2014) M. Cui et al.   JOURNAL OF IMMUNOLOGY

Tat-Induced FOXO3a Is a Key Mediator of Apoptosis in HIV-1-Infected Human CD4+ T Lymphocytes

(2014) A. Dabrowska et al.   JOURNAL OF IMMUNOLOGY

Immunopathogenesis of HTLV-1-assoaciated myelopathy/tropical spastic paraparesis (HAM/TSP)

(2014) Hellen Thais Fuzii et al.   LIFE SCIENCES

Loss of NDRG2 expression activates PI3K-AKT signalling via PTEN phosphorylation in ATLL and other cancers

(2014) Shingo Nakahata et al.   Nature Communications

HTLV-1 bZIP Factor Suppresses Apoptosis by Attenuating the Function of FoxO3a and Altering Its Localization

(2013) A. Tanaka-Nakanishi et al.   CANCER RESEARCH

Human SNP Links Differential Outcomes in Inflammatory and Infectious Disease to a FOXO3-Regulated Pathway

(2013) James C. Lee et al.   CELL

Host Restriction Factor SAMHD1 Limits Human T Cell Leukemia Virus Type 1 Infection of Monocytes via STING-Mediated Apoptosis

(2013) Alexandre Sze et al.   Cell Host & Microbe

The Small GTPase RALA Controls c-Jun N-terminal Kinase-mediated FOXO Activation by Regulation of a JIP1 Scaffold Complex

(2013) Maaike C. W. van den Berg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of exogenous interleukin-7 on CD8(+) T-cell survival and function in human T-cell lymphotropic virus type 1 infection

(2013) Yohann White et al.   LEUKEMIA & LYMPHOMA

Therapeutic Options for Adult T-Cell Leukemia/Lymphoma

(2013) Ambroise Marçais et al.   Current Oncology Reports

Highlights on distinctive structural and functional properties of HTLV Tax proteins

(2013) Maria Grazia Romanelli et al.   Frontiers in Microbiology

Foxo3a: An integrator of immune dysfunction during HIV infection

(2012) Julien van Grevenynghe et al.   CYTOKINE & GROWTH FACTOR REVIEWS

HTLV-1: Persistence and pathogenesis

(2012) Lucy B. Cook et al.   VIROLOGY

Systems Biology Approaches Reveal a Specific Interferon-Inducible Signature in HTLV-1 Associated Myelopathy

(2012) Sonja Tattermusch et al.   PLoS Pathogens

Deciphering the Role of Forkhead Transcription Factors in Cancer Therapy

(2011) Jer-Yen Yang et al.   CURRENT DRUG TARGETS

The Complex Biology of FOXO

(2011) Maria Monsalve et al.   CURRENT DRUG TARGETS

Modulation of innate immune responses during human T-cell leukemia virus (HTLV-1) pathogenesis

(2011) Stéphanie Olière et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Outfoxing FoxO transcription factors: HTLV-1 Tax oncoprotein inactivates FoxO4 via the ubiquitin–proteasome pathway

(2011) Noula Shembade et al.   Future Virology

Loss of memory B cells during chronic HIV infection is driven by Foxo3a- and TRAIL-mediated apoptosis

(2011) Julien van Grevenynghe et al.   JOURNAL OF CLINICAL INVESTIGATION

The Human T-Cell Leukemia Virus Type 1 Oncoprotein Tax Controls Forkhead Box O4 Activity through Degradation by the Proteasome

(2011) A. Oteiza et al.   JOURNAL OF VIROLOGY

Human T Cell Leukemia Virus Type 1 Tax Inhibits Innate Antiviral Signaling via NF- B-Dependent Induction of SOCS1

(2011) S. Charoenthongtrakul et al.   JOURNAL OF VIROLOGY

HTLV-I Tax-dependent and -independent events associated with immortalization of human primary T lymphocytes

(2010) M. Bellon et al.   BLOOD

Akt inhibitors in clinical development for the treatment of cancer

(2010) Sumanta Kumar Pal et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Abelson virus transformation prevents TRAIL expression by inhibiting FoxO3a and NF-κB

(2010) Mary K. Wilson et al.   MOLECULES AND CELLS

Activation of the PI3K–Akt pathway by human T cell leukemia virus type 1 (HTLV-1) oncoprotein Tax increases Bcl3 expression, which is associated with enhanced growth of HTLV-1-infected T cells

(2010) Kousuke Saito et al.   VIROLOGY

HTLV-1 Evades Type I Interferon Antiviral Signaling by Inducing the Suppressor of Cytokine Signaling 1 (SOCS1)

(2010) Stéphanie Olière et al.   PLoS Pathogens

Association of Tat with Promoters of PTEN and PP2A Subunits Is Key to Transcriptional Activation of Apoptotic Pathways in HIV-Infected CD4+ T Cells

(2010) Nayoung Kim et al.   PLoS Pathogens

Kinetic Analysis of Human T-Cell Leukemia Virus Type 1 Gene Expression in Cell Culture and Infected Animals

(2009) M. Li et al.   JOURNAL OF VIROLOGY

In vivo expression of the HBZ gene of HTLV-1 correlates with proviral load, inflammatory markers and disease severity in HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

(2009) Mineki Saito et al.   Retrovirology

Transcription factor FOXO3a controls the persistence of memory CD4+ T cells during HIV infection

(2008) Julien van Grevenynghe et al.   NATURE MEDICINE

Cell-free HTLV-1 infects dendritic cells leading to transmission and transformation of CD4+ T cells

(2008) Kathryn S Jones et al.   NATURE MEDICINE

The FoxO code

(2008) D R Calnan et al.   ONCOGENE

The HTLV-1 Tax interactome

(2008) Mathieu Boxus et al.   Retrovirology

Lymph node architecture collapse and consequent modulation of FOXO3a pathway on memory T- and B-cells during HIV infection

(2008) Julien van Grevenynghe et al.   SEMINARS IN IMMUNOLOGY