Prion Strains and Amyloid Polymorphism Influence Phenotypic Variation

Distinct Prion Strains Are Defined by Amyloid Core Structure and Chaperone Binding Site Dynamics

(2014) Kendra K. Frederick et al.   CHEMISTRY & BIOLOGY

Wild yeast harbour a variety of distinct amyloid structures with strong prion-inducing capabilities

(2014) Laura Westergard et al.   MOLECULAR MICROBIOLOGY

Extracellular environment modulates the formation and propagation of particular amyloid structures

(2014) Laura Westergard et al.   MOLECULAR MICROBIOLOGY

The structure of the infectious prion protein

(2014) Jesús R Requena et al.   Prion

Extensive Diversity of Prion Strains Is Defined by Differential Chaperone Interactions and Distinct Amyloidogenic Regions

(2014) Kevin C. Stein et al.   PLoS Genetics

Conformational Stability of Mammalian Prion Protein Amyloid Fibrils Is Dictated by a Packing Polymorphism within the Core Region

(2013) Nathan J. Cobb et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spontaneous Variants of the [RNQ+] Prion in Yeast Demonstrate the Extensive Conformational Diversity Possible with Prion Proteins

(2013) Vincent J. Huang et al.   PLoS One

Elucidating the role of cofactors in mammalian prion propagation

(2013) Surachai Supattapone   Prion

The Amyloid State of Proteins in Human Diseases

(2012) David Eisenberg et al.   CELL

Prions in Yeast

(2012) S. W. Liebman et al.   GENETICS

The [RNQ+] prion: A model of both functional and pathological amyloid

(2012) Kevin C. Stein et al.   Prion

Environmental Regulation of Prions in Yeast

(2012) Liming Li et al.   PLoS Pathogens

Amyloid Structure: Conformational Diversity and Consequences

(2011) Brandon H. Toyama et al.   Annual Review of Biochemistry

Prediction of amyloid aggregation in vivo

(2011) Mattia Belli et al.   EMBO REPORTS

Structural organization of brain-derived mammalian prions examined by hydrogen-deuterium exchange

(2011) Vytautas Smirnovas et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Prions

(2011) D. W. Colby et al.   Cold Spring Harbor Perspectives in Biology

The Strain-Encoded Relationship between PrPSc Replication, Stability and Processing in Neurons is Predictive of the Incubation Period of Disease

(2011) Jacob I. Ayers et al.   PLoS Pathogens

Protease-Sensitive Conformers in Broad Spectrum of Distinct PrPSc Structures in Sporadic Creutzfeldt-Jakob Disease Are Indicator of Progression Rate

(2011) Chae Kim et al.   PLoS Pathogens

Analysis of the [RNQ+] Prion Reveals Stability of Amyloid Fibers as the Key Determinant of Yeast Prion Variant Propagation

(2010) Tejas Kalastavadi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prion Strain Mutation Determined by Prion Protein Conformational Compatibility and Primary Structure

(2010) R. C. Angers et al.   SCIENCE

Molecular mechanisms for protein-encoded inheritance

(2009) Jed J W Wiltzius et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Design and construction of diverse mammalian prion strains

(2009) D. W. Colby et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chaperone-dependent amyloid assembly protects cells from prion toxicity

(2008) P. M. Douglas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA