Understanding Human Variation in Infectious Disease Susceptibility through Clinical and Cellular GWAS

Integration of Cell Line and Clinical Trial Genome-Wide Analyses Supports a Polygenic Architecture of Paclitaxel-Induced Sensory Peripheral Neuropathy

(2012) H. E. Wheeler et al.   CLINICAL CANCER RESEARCH

Interleukin-28B polymorphisms on the SVR in the treatment of naïve chronic hepatitis C with pegylated interferon-α plus ribavirin: A meta-analysis

(2012) Ke-Qing Shi et al.   GENE

Introduction to the genetics and biology of interleukin-28B

(2012) Thomas Urban et al.   HEPATOLOGY

The Promise and Limitations of Genome-wide Association Studies

(2012) Christine Klein et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

Evolution, revolution and heresy in the genetics of infectious disease susceptibility

(2012) A. V. S. Hill   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Functional genetic screen of human diversity reveals that a methionine salvage enzyme regulates inflammatory cell death

(2012) D. C. Ko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mapping Rare and Common Causal Alleles for Complex Human Diseases

(2011) Soumya Raychaudhuri   CELL

Identification of two new loci at IL23R and RAB32 that influence susceptibility to leprosy

(2011) Furen Zhang et al.   NATURE GENETICS

GWASdb: a database for human genetic variants identified by genome-wide association studies

(2011) Mulin Jun Li et al.   NUCLEIC ACIDS RESEARCH

Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

(2011) Tomas Cermak et al.   NUCLEIC ACIDS RESEARCH

Chemotherapeutic-induced apoptosis

(2011) Yujia Wen et al.   Pharmacogenetics and Genomics

Signatures of Environmental Genetic Adaptation Pinpoint Pathogens as the Main Selective Pressure through Human Evolution

(2011) Matteo Fumagalli et al.   PLoS Genetics

Tracking a century of global expansion and evolution of HIV to drive understanding and to combat disease

(2010) Denis M Tebit et al.   LANCET INFECTIOUS DISEASES

Genetics and Beyond – The Transcriptome of Human Monocytes and Disease Susceptibility

(2010) Tanja Zeller et al.   PLoS One

A Genome-wide In Vitro Bacterial-Infection Screen Reveals Human Variation in the Host Response Associated with Inflammatory Disease

(2009) Dennis C. Ko et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

(2009) Dongliang Ge et al.   NATURE

Activation of innate immune antiviral responses by Nod2

(2009) Ahmed Sabbah et al.   NATURE IMMUNOLOGY

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

(2009) Leonardo H Travassos et al.   NATURE IMMUNOLOGY

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

(2009) Rachel Cooney et al.   NATURE MEDICINE

Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY

Genomewide Association Study of Leprosy

(2009) Fu-Ren Zhang et al.   NEW ENGLAND JOURNAL OF MEDICINE

In Vitro Whole-Genome Analysis Identifies a Susceptibility Locus for HIV-1

(2008) Corinne Loeuillet et al.   PLOS BIOLOGY