Modeling Host Genetic Regulation of Influenza Pathogenesis in the Collaborative Cross

CCR2+ Monocyte-Derived Dendritic Cells and Exudate Macrophages Produce Influenza-Induced Pulmonary Immune Pathology and Mortality

(2014) K. L. Lin et al.   JOURNAL OF IMMUNOLOGY

Discovery of novel variants in genotyping arrays improves genotype retention and reduces ascertainment bias

(2012) John P Didion et al.   BMC GENOMICS

Distinct gene loci control the host response to influenza H1N1 virus infection in a time-dependent manner

(2012) Tatiana Nedelko et al.   BMC GENOMICS

Rational Design of Small Molecule Inhibitors Targeting the Rac GTPase-p67phox Signaling Axis in Inflammation

(2012) Emily E. Bosco et al.   CHEMISTRY & BIOLOGY

Mapping of Clinical and Expression Quantitative Trait Loci in a Sex-Dependent Effect of Host Susceptibility to Mouse-Adapted Influenza H3N2/HK/1/68

(2012) G. A. Boivin et al.   JOURNAL OF IMMUNOLOGY

Complicated Secondary Pneumonia after Swine-Origin Influenza A Virus Infection in an Immunocompetent Patient

(2012) Ryotaro Igusa et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Genetic Analysis of Hematological Parameters in Incipient Lines of the Collaborative Cross

(2012) Samir N. P. Kelada et al.   G3-Genes Genomes Genetics

Negative Regulation of Lung Inflammation and Immunopathology by TNF-α during Acute Influenza Infection

(2011) Daniela Damjanovic et al.   AMERICAN JOURNAL OF PATHOLOGY

Genome-wide association studies and susceptibility to infectious diseases

(2011) M. J. Newport et al.   Briefings in Functional Genomics

Acute Respiratory Distress Syndrome as a presenting manifestation in young patients infected with H1N1 influenza virus

(2011) Dirk Pabst et al.   European Journal of Internal Medicine

Genetic analysis in the Collaborative Cross breeding population

(2011) Vivek M. Philip et al.   GENOME RESEARCH

Genetic analysis of complex traits in the emerging Collaborative Cross

(2011) David L. Aylor et al.   GENOME RESEARCH

RhoG is required for both FcγR- and CR3-mediated phagocytosis

(2011) George Tzircotis et al.   JOURNAL OF CELL SCIENCE

Influence of host genetic and ecological factors in complex concomitant infections – relevance to sexually transmitted infections

(2011) Sadeep Shrestha   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Mouse genomic variation and its effect on phenotypes and gene regulation

(2011) Thomas M. Keane et al.   NATURE

Subspecific origin and haplotype diversity in the laboratory mouse

(2011) Hyuna Yang et al.   NATURE GENETICS

Systems biology of vaccination for seasonal influenza in humans

(2011) Helder I Nakaya et al.   NATURE IMMUNOLOGY

Critical findings of severe influenza A (H1N1) pneumonia in children

(2011) Hidetoshi Ishigaki et al.   PEDIATRICS INTERNATIONAL

Virus-induced acute respiratory distress syndrome: Epidemiology, management and outcome

(2011) Charles-Édouard Luyt et al.   PRESSE MEDICALE

Pathogenesis of the 1918 Pandemic Influenza Virus

(2011) Tokiko Watanabe et al.   PLoS Pathogens

Evasion of innate and adaptive immune responses by influenza A virus

(2010) Mirco Schmolke et al.   CELLULAR MICROBIOLOGY

Influenza A (H1N1) virus-associated pneumonia: High-resolution computed tomography–pathologic correlation

(2010) Edson Marchiori et al.   EUROPEAN JOURNAL OF RADIOLOGY

Genetic Variation in IL28B Is Associated With Chronic Hepatitis C and Treatment Failure: A Genome-Wide Association Study

(2010) Andri Rauch et al.   GASTROENTEROLOGY

Clinical presentation and response to treatment of novel influenza A H1N1 in a university-based summer camp population

(2010) Ephraim L. Tsalik et al.   JOURNAL OF CLINICAL VIROLOGY

Lung Pathology in Fatal Novel Human Influenza A (H1N1) Infection

(2009) Thais Mauad et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Signed weighted gene co-expression network analysis of transcriptional regulation in murine embryonic stem cells

(2009) Mike J Mason et al.   BMC GENOMICS

A Physical and Regulatory Map of Host-Influenza Interactions Reveals Pathways in H1N1 Infection

(2009) Sagi D. Shapira et al.   CELL

The IFITM Proteins Mediate Cellular Resistance to Influenza A H1N1 Virus, West Nile Virus, and Dengue Virus

(2009) Abraham L. Brass et al.   CELL

Gene Expression Signatures Diagnose Influenza and Other Symptomatic Respiratory Viral Infections in Humans

(2009) Aimee K. Zaas et al.   Cell Host & Microbe

Mapping in Structured Populations by Resample Model Averaging

(2009) William Valdar et al.   GENETICS

A New Standard Genetic Map for the Laboratory Mouse

(2009) Allison Cox et al.   GENETICS

Outcome of critically ill patients with influenza virus infection

(2009) Guangxi Li et al.   JOURNAL OF CLINICAL VIROLOGY

Mannose-Binding Lectin Deficiency and Respiratory Tract Infection

(2009) Damon P. Eisen   Journal of Innate Immunity

Host Genetic Variation Affects Resistance to Infection with a Highly Pathogenic H5N1 Influenza A Virus in Mice

(2009) A. C. M. Boon et al.   JOURNAL OF VIROLOGY

Host Genetic Background Strongly Influences the Response to Influenza A Virus Infections

(2009) Barkha Srivastava et al.   PLoS One

Complications of Viral Influenza

(2008) Michael B. Rothberg et al.   AMERICAN JOURNAL OF MEDICINE

Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury

(2008) Yumiko Imai et al.   CELL

Host Responses to Wild-Type and Attenuated Herpes Simplex Virus Infection in the Absence of Stat1

(2008) T. J. Pasieka et al.   JOURNAL OF VIROLOGY

The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics

(2008) Elissa J. Chesler et al.   MAMMALIAN GENOME

Effect of polymorphisms within probe–target sequences on olignonucleotide microarray experiments

(2008) David Benovoy et al.   NUCLEIC ACIDS RESEARCH

Clinical Characteristics of 26 Human Cases of Highly Pathogenic Avian Influenza A (H5N1) Virus Infection in China

(2008) Hongjie Yu et al.   PLoS One

H5N1 and 1918 Pandemic Influenza Virus Infection Results in Early and Excessive Infiltration of Macrophages and Neutrophils in the Lungs of Mice

(2008) Lucy A. Perrone et al.   PLoS Pathogens

Evidence for a Heritable Predisposition to Death Due to Influenza

(2007) Frederick S. Albright et al.   JOURNAL OF INFECTIOUS DISEASES