Vpu Binds Directly to Tetherin and Displaces It from Nascent Virions

Ubiquitination of BST-2 Protein by HIV-1 Vpu Protein Does Not Require Lysine, Serine, or Threonine Residues within the BST-2 Cytoplasmic Domain

(2012) Jean K. Gustin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Cytoplasmic Tail Determinant in HIV-1 Vpu Mediates Targeting of Tetherin for Endosomal Degradation and Counteracts Interferon-Induced Restriction

(2012) Tonya Kueck et al.   PLoS Pathogens

HIV-1 Vpu Protein Antagonizes Innate Restriction Factor BST-2 via Lipid-embedded Helix-Helix Interactions

(2011) Mark Skasko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Feline Tetherin Efficiently Restricts Release of Feline Immunodeficiency Virus but Not Spreading of Infection

(2011) I. Dietrich et al.   JOURNAL OF VIROLOGY

Separable Determinants of Subcellular Localization and Interaction Account for the Inability of Group O HIV-1 Vpu To Counteract Tetherin

(2011) R. Vigan et al.   JOURNAL OF VIROLOGY

β-TrCP is dispensable for Vpu's ability to overcome the CD317/Tetherin-imposed restriction to HIV-1 release

(2011) Hanna-Mari Tervo et al.   Retrovirology

BST-2 is rapidly down-regulated from the cell surface by the HIV-1 protein Vpu: Evidence for a post-ER mechanism of Vpu-action

(2011) Mark Skasko et al.   VIROLOGY

Tetherin inhibits prototypic foamy virus release

(2011) Fengwen Xu et al.   Virology Journal

HIV-1 Vpu Blocks Recycling and Biosynthetic Transport of the Intrinsic Immunity Factor CD317/Tetherin To Overcome the Virion Release Restriction

(2011) S. Schmidt et al.   mBio

SIV Nef Proteins Recruit the AP-2 Complex to Antagonize Tetherin and Facilitate Virion Release

(2011) Fengwen Zhang et al.   PLoS Pathogens

Structural and Biophysical Analysis of BST-2/Tetherin Ectodomains Reveals an Evolutionary Conserved Design to Inhibit Virus Release

(2010) Melissa Swiecki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interferon-Induced Cell Membrane Proteins, IFITM3 and Tetherin, Inhibit Vesicular Stomatitis Virus Infection via Distinct Mechanisms

(2010) J. M. Weidner et al.   JOURNAL OF VIROLOGY

Identification of Amino Acids in the Human Tetherin Transmembrane Domain Responsible for HIV-1 Vpu Interaction and Susceptibility

(2010) T. Kobayashi et al.   JOURNAL OF VIROLOGY

Differential Effects of Human Immunodeficiency Virus Type 1 Vpu on the Stability of BST-2/Tetherin

(2010) A. J. Andrew et al.   JOURNAL OF VIROLOGY

Serine-Threonine Ubiquitination Mediates Downregulation of BST-2/Tetherin and Relief of Restricted Virion Release by HIV-1 Vpu

(2010) A. A. Tokarev et al.   JOURNAL OF VIROLOGY

Determinants of Tetherin Antagonism in the Transmembrane Domain of the Human Immunodeficiency Virus Type 1 Vpu Protein

(2010) R. Vigan et al.   JOURNAL OF VIROLOGY

Infectious Lassa Virus, but Not Filoviruses, Is Restricted by BST-2/Tetherin

(2010) Sheli R. Radoshitzky et al.   JOURNAL OF VIROLOGY

Structural insight into the mechanisms of enveloped virus tethering by tetherin

(2010) H. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural and functional studies on the extracellular domain of BST2/tetherin in reduced and oxidized conformations

(2010) H. L. Schubert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vpu serine 52 dependent counteraction of tetherin is required for HIV-1 replication in macrophages, but not in ex vivo human lymphoid tissue

(2010) Michael Schindler et al.   Retrovirology

HIV-1 Vpu and HIV-2 Env counteract BST-2/tetherin by sequestration in a perinuclear compartment

(2010) Heiko Hauser et al.   Retrovirology

Functional Interchangeability of Late Domains, Late Domain Cofactors and Ubiquitin in Viral Budding

(2010) Maria Zhadina et al.   PLoS Pathogens

The RING-CH Ligase K5 Antagonizes Restriction of KSHV and HIV-1 Particle Release by Mediating Ubiquitin-Dependent Endosomal Degradation of Tetherin

(2010) Claire Pardieu et al.   PLoS Pathogens

Antagonism of Tetherin Restriction of HIV-1 Release by Vpu Involves Binding and Sequestration of the Restriction Factor in a Perinuclear Compartment

(2010) Mathieu Dubé et al.   PLoS Pathogens

Immunoelectron Microscopic Evidence for Tetherin/BST2 as the Physical Bridge between HIV-1 Virions and the Plasma Membrane

(2010) Jason Hammonds et al.   PLoS Pathogens

Direct Restriction of Virus Release and Incorporation of the Interferon-Induced Protein BST-2 into HIV-1 Particles

(2010) Kathleen Fitzpatrick et al.   PLoS Pathogens

Antiviral Activity of the Interferon-Induced Cellular Protein BST-2/Tetherin

(2009) Andrey Tokarev et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Tetherin Inhibits HIV-1 Release by Directly Tethering Virions to Cells

(2009) David Perez-Caballero et al.   CELL

HIV-1 Accessory Protein Vpu Internalizes Cell-surface BST-2/Tetherin through Transmembrane Interactions Leading to Lysosomes

(2009) Yukie Iwabu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Suppression of Tetherin-Restricting Activity upon Human Immunodeficiency Virus Type 1 Particle Release Correlates with Localization of Vpu in the trans-Golgi Network

(2009) M. Dube et al.   JOURNAL OF VIROLOGY

Regulation of Porcine Endogenous Retrovirus Release by Porcine and Human Tetherins

(2009) G. Mattiuzzo et al.   JOURNAL OF VIROLOGY

The Transmembrane Domain of BST-2 Determines Its Sensitivity to Down-Modulation by Human Immunodeficiency Virus Type 1 Vpu

(2009) L. Rong et al.   JOURNAL OF VIROLOGY

Vpu Directs the Degradation of the Human Immunodeficiency Virus Restriction Factor BST-2/Tetherin via a  TrCP-Dependent Mechanism

(2009) J. L. Douglas et al.   JOURNAL OF VIROLOGY

Molecular Mechanism of BST2/Tetherin Downregulation by K5/MIR2 of Kaposi's Sarcoma-Associated Herpesvirus

(2009) M. Mansouri et al.   JOURNAL OF VIROLOGY

Dimerization of Tetherin Is Not Essential for Its Antiviral Activity against Lassa and Marburg Viruses

(2009) Toshie Sakuma et al.   PLoS One

Vpu enhances HIV-1 virus release in the absence of Bst-2 cell surface down-modulation and intracellular depletion

(2009) Eri Miyagi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tetherin-mediated restriction of filovirus budding is antagonized by the Ebola glycoprotein

(2009) Rachel L. Kaletsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparative study on the effect of human BST-2/Tetherin on HIV-1 release in cells of various species

(2009) Kei Sato et al.   Retrovirology

Mutation of a Single Residue Renders Human Tetherin Resistant to HIV-1 Vpu-Mediated Depletion

(2009) Ravindra K. Gupta et al.   PLoS Pathogens

HIV-1 Vpu Neutralizes the Antiviral Factor Tetherin/BST-2 by Binding It and Directing Its Beta-TrCP2-Dependent Degradation

(2009) Bastien Mangeat et al.   PLoS Pathogens

Species-Specific Activity of HIV-1 Vpu and Positive Selection of Tetherin Transmembrane Domain Variants

(2009) Matthew W. McNatt et al.   PLoS Pathogens

Vpu Antagonizes BST-2–Mediated Restriction of HIV-1 Release via β-TrCP and Endo-Lysosomal Trafficking

(2009) Richard S. Mitchell et al.   PLoS Pathogens

Species-Specific Activity of SIV Nef and HIV-1 Vpu in Overcoming Restriction by Tetherin/BST2

(2009) Bin Jia et al.   PLoS Pathogens

The Interferon-Induced Protein BST-2 Restricts HIV-1 Release and Is Downregulated from the Cell Surface by the Viral Vpu Protein

(2008) Nanette Van Damme et al.   Cell Host & Microbe

Inhibition of Lassa and Marburg Virus Production by Tetherin

(2008) T. Sakuma et al.   JOURNAL OF VIROLOGY

Broad-Spectrum Inhibition of Retroviral and Filoviral Particle Release by Tetherin

(2008) N. Jouvenet et al.   JOURNAL OF VIROLOGY

Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu

(2008) Stuart J. D. Neil et al.   NATURE