Genome-wide RNAi Screen Reveals a New Role of a WNT/CTNNB1 Signaling Pathway as Negative Regulator of Virus-induced Innate Immune Responses

RNA Helicase DDX3 Is a Regulatory Subunit of Casein Kinase 1 in Wnt- -Catenin Signaling

(2013) C.-M. Cruciat et al.   SCIENCE

β-catenin regulates innate and adaptive immunity in mouse liver ischemia-reperfusion injury

(2012) Bibo Ke et al.   HEPATOLOGY

Transactivation of Inducible Nitric Oxide Synthase Gene by Kruppel-like Factor 6 Regulates Apoptosis during Influenza A Virus Infection

(2012) V. Mgbemena et al.   JOURNAL OF IMMUNOLOGY

The Akt1 Isoform Is Required for Optimal IFN-  Transcription through Direct Phosphorylation of  -Catenin

(2012) B. N. Gantner et al.   JOURNAL OF IMMUNOLOGY

Hepatitis C Virus Induces Epithelial-Mesenchymal Transition in Primary Human Hepatocytes

(2012) S. K. Bose et al.   JOURNAL OF VIROLOGY

Glycogen synthase kinase-3 beta inhibitor suppresses Porphyromonas gingivalis lipopolysaccharide-induced CD40 expression by inhibiting nuclear factor-kappa B activation in mouse osteoblasts

(2012) Liu Die et al.   MOLECULAR IMMUNOLOGY

Wingless homolog Wnt11 suppresses bacterial invasion and inflammation in intestinal epithelial cells

(2011) Xingyin Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

PKC alpha regulates Sendai virus-mediated interferon induction through HDAC6 and β-catenin

(2011) Jianzhong Zhu et al.   EMBO JOURNAL

Wnt2 inhibits enteric bacterial-induced inflammation in intestinal epithelial cells

(2011) Xingyin Liu et al.   INFLAMMATORY BOWEL DISEASES

Y-Box-Binding Protein 1 Interacts with Hepatitis C Virus NS3/4A and Influences the Equilibrium between Viral RNA Replication and Infectious Particle Production

(2011) L. Chatel-Chaix et al.   JOURNAL OF VIROLOGY

Non-apoptotic role of BID in inflammation and innate immunity

(2011) Garabet Yeretssian et al.   NATURE

A diverse range of gene products are effectors of the type I interferon antiviral response

(2011) John W. Schoggins et al.   NATURE

Frizzled1 is a marker of inflammatory macrophages, and its ligand Wnt3a is involved in reprogramming Mycobacterium tuberculosis-infected macrophages

(2010) Jan Neumann et al.   FASEB JOURNAL

Glycogen Synthase Kinase 3β Regulates IRF3 Transcription Factor-Mediated Antiviral Response via Activation of the Kinase TBK1

(2010) Cao-Qi Lei et al.   IMMUNITY

Genome-Wide RNA Interference in Drosophila Cells Identifies G Protein-Coupled Receptor Kinase 2 as a Conserved Regulator of NF- B Signaling

(2010) S. Valanne et al.   JOURNAL OF IMMUNOLOGY

Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication

(2010) Alexander Karlas et al.   NATURE

The transcription factor MafB antagonizes antiviral responses by blocking recruitment of coactivators to the transcription factor IRF3

(2010) Hwijin Kim et al.   NATURE IMMUNOLOGY

The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a β-catenin-dependent pathway

(2010) Pengyuan Yang et al.   NATURE IMMUNOLOGY

How the Noninflammasome NLRs Function in the Innate Immune System

(2010) J. P. Y. Ting et al.   SCIENCE

A Physical and Regulatory Map of Host-Influenza Interactions Reveals Pathways in H1N1 Infection

(2009) Sagi D. Shapira et al.   CELL

3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione (SB216763), a Glycogen Synthase Kinase-3 Inhibitor, Displays Therapeutic Properties in a Mouse Model of Pulmonary Inflammation and Fibrosis

(2009) C. Gurrieri et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Primary cultures of human hepatocytes isolated from hepatitis C virus-infected cirrhotic livers as a model to study hepatitis C infection

(2009) Valérie-Ann Raymond et al.   LIVER INTERNATIONAL

Human host factors required for influenza virus replication

(2009) Renate König et al.   NATURE

A genome-wide genetic screen for host factors required for hepatitis C virus propagation

(2009) Q. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Wide RNAi Screen Identifies Genes Involved in Intestinal Pathogenic Bacterial Infection

(2009) S. J. F. Cronin et al.   SCIENCE

Innate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3)

(2009) Eléonore Beurel et al.   TRENDS IN IMMUNOLOGY

Global Analysis of Host-Pathogen Interactions that Regulate Early-Stage HIV-1 Replication

(2008) Renate König et al.   CELL

Genome-Scale RNAi Screen for Host Factors Required for HIV Replication

(2008) Honglin Zhou et al.   Cell Host & Microbe

Glycogen synthase kinase-3 regulates microglial migration, inflammation, and inflammation-induced neurotoxicity

(2008) Christopher J. Yuskaitis et al.   CELLULAR SIGNALLING

Negative regulation of cytoplasmic RNA-mediated antiviral signaling

(2008) Akihiko Komuro et al.   CYTOKINE

The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response

(2008) Didier Soulat et al.   EMBO JOURNAL

Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKɛ-mediated IRF activation

(2008) Martina Schröder et al.   EMBO JOURNAL

Antiviral Suppression vs Restoration of RIG-I Signaling by Hepatitis C Protease and Polymerase Inhibitors

(2008) Yuqiong Liang et al.   GASTROENTEROLOGY

Glycogen Synthase Kinase 3 Inhibition Protects the Heart From Acute Ischemia-Reperfusion Injury Via Inhibition of Inflammation and Apoptosis

(2008) Hao-Kao Gao et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

MAVS Dimer Is a Crucial Signaling Component of Innate Immunity and the Target of Hepatitis C Virus NS3/4A Protease

(2008) M. Baril et al.   JOURNAL OF VIROLOGY

NLRX1 is a regulator of mitochondrial antiviral immunity

(2008) Chris B. Moore et al.   NATURE

RNA interference screen for human genes associated with West Nile virus infection

(2008) Manoj N. Krishnan et al.   NATURE

Identification of Host Proteins Required for HIV Infection Through a Functional Genomic Screen

(2008) Abraham L. Brass et al.   SCIENCE