Haploid Genetic Screens Identify an Essential Role for PLP2 in the Downregulation of Novel Plasma Membrane Targets by Viral E3 Ubiquitin Ligases

Deciphering the Glycosylome of Dystroglycanopathies Using Haploid Screens for Lassa Virus Entry

(2013) L. T. Jae et al.   SCIENCE

Latency-Associated Degradation of the MRP1 Drug Transporter During Latent Human Cytomegalovirus Infection

(2013) M. P. Weekes et al.   SCIENCE

Multivariate proteomic profiling identifies novel accessory proteins of coated vesicles

(2012) Georg H.H. Borner et al.   JOURNAL OF CELL BIOLOGY

Proteomic Plasma Membrane Profiling Reveals an Essential Role for gp96 in the Cell Surface Expression of LDLR Family Members, Including the LDL Receptor and LRP6

(2012) Michael P. Weekes et al.   JOURNAL OF PROTEOME RESEARCH

Construction and Manipulation of a New Kaposi's Sarcoma-Associated Herpesvirus Bacterial Artificial Chromosome Clone

(2012) Kevin F. Brulois et al.   JOURNAL OF VIROLOGY

MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors

(2012) Kivanç Birsoy et al.   NATURE GENETICS

Fluorescence-Based Phenotypic Selection Allows Forward Genetic Screens in Haploid Human Cells

(2012) Lidia M. Duncan et al.   PLoS One

Attachment of Chlamydia trachomatis L2 to host cells requires sulfation

(2012) D. M. Rosmarin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumor Necrosis Factor Signaling Requires iRhom2 to Promote Trafficking and Activation of TACE

(2012) C. Adrain et al.   SCIENCE

iRhom2 Regulation of TACE Controls TNF-Mediated Protection Against Listeria and Responses to LPS

(2012) D. R. McIlwain et al.   SCIENCE

Diverse roles for semaphorin−plexin signaling in the immune system

(2012) Hyota Takamatsu et al.   TRENDS IN IMMUNOLOGY

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

Ebola virus entry requires the cholesterol transporter Niemann–Pick C1

(2011) Jan E. Carette et al.   NATURE

Global gene disruption in human cells to assign genes to phenotypes by deep sequencing

(2011) Jan E Carette et al.   NATURE BIOTECHNOLOGY

BAP31 and BiP are essential for dislocation of SV40 from the endoplasmic reticulum to the cytosol

(2011) Roger Geiger et al.   NATURE CELL BIOLOGY

Synaptophysin Regulates the Kinetics of Synaptic Vesicle Endocytosis in Central Neurons

(2011) Sung E. Kwon et al.   NEURON

Lipolysis-stimulated lipoprotein receptor (LSR) is the host receptor for the binary toxin Clostridium difficile transferase (CDT)

(2011) P. Papatheodorou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A haploid genetic screen identifies the major facilitator domain containing 2A (MFSD2A) transporter as a key mediator in the response to tunicamycin

(2011) J. H. Reiling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Contribution of Lysine 11-linked Ubiquitination to MIR2-mediated Major Histocompatibility Complex Class I Internalization

(2010) Eiji Goto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Ubiquitous Chromatin Opening Element (UCOE) Confers Resistance to DNA Methylation–mediated Silencing of Lentiviral Vectors

(2010) Fang Zhang et al.   MOLECULAR THERAPY

Membrane-Associated RING-CH Proteins Associate with Bap31 and Target CD81 and CD44 to Lysosomes

(2010) Eric Bartee et al.   PLoS One

Ubiquitination of lysine-331 by Kaposi's sarcoma-associated herpesvirus protein K5 targets HFE for lysosomal degradation

(2010) D. A. Rhodes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The RING-CH Ligase K5 Antagonizes Restriction of KSHV and HIV-1 Particle Release by Mediating Ubiquitin-Dependent Endosomal Degradation of Tetherin

(2010) Claire Pardieu et al.   PLoS Pathogens

Dre recombinase, like Cre, is a highly efficient site-specific recombinase in E. coli, mammalian cells and mice

(2009) K. Anastassiadis et al.   Disease Models & Mechanisms

Molecular Mechanism of BST2/Tetherin Downregulation by K5/MIR2 of Kaposi's Sarcoma-Associated Herpesvirus

(2009) M. Mansouri et al.   JOURNAL OF VIROLOGY

Stable Isotope Labeling by Amino Acids in Cell Culture and Differential Plasma Membrane Proteome Quantitation Identify New Substrates for the MARCH9 Transmembrane E3 Ligase

(2009) Simon Hör et al.   MOLECULAR & CELLULAR PROTEOMICS

Viral avoidance and exploitation of the ubiquitin system

(2009) Felix Randow et al.   NATURE CELL BIOLOGY

A high-throughput splinkerette-PCR method for the isolation and sequencing of retroviral insertion sites

(2009) Anthony G Uren et al.   Nature Protocols

Haploid Genetic Screens in Human Cells Identify Host Factors Used by Pathogens

(2009) J. E. Carette et al.   SCIENCE

Efficient Internalization of MHC I Requires Lysine-11 and Lysine-63 Mixed Linkage Polyubiquitin Chains

(2009) Jessica M. Boname et al.   TRAFFIC

Eph-Ephrin Bidirectional Signaling in Physiology and Disease

(2008) Elena B. Pasquale   CELL

The trafficking and regulation of membrane receptors by the RING-CH ubiquitin E3 ligases

(2008) James A. Nathan et al.   EXPERIMENTAL CELL RESEARCH

Modulation of natural killer cells by human cytomegalovirus

(2008) Gavin W.G. Wilkinson et al.   JOURNAL OF CLINICAL VIROLOGY

UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

(2008) You-Me Kim et al.   NATURE

Down-regulation of NKG2D and NKp80 ligands by Kaposi's sarcoma-associated herpesvirus K5 protects against NK cell cytotoxicity

(2008) M. Thomas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA