The EBV Latent Antigen 3C Inhibits Apoptosis through Targeted Regulation of Interferon Regulatory Factors 4 and 8

Lenalidomide downregulates the cell survival factor, interferon regulatory factor-4, providing a potential mechanistic link for predicting response

(2011) Antonia Lopez-Girona et al.   BRITISH JOURNAL OF HAEMATOLOGY

Tumor viruses and cancer biology: Modulating signaling pathways for therapeutic intervention

(2011) Abhik Saha et al.   CANCER BIOLOGY & THERAPY

Interferon Regulatory Factor 4 (IRF-4) Targets IRF-5 to Regulate Epstein-Barr Virus Transformation

(2011) Dongsheng Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oncogenic IRFs Provide a Survival Advantage for Epstein-Barr Virus- or Human T-Cell Leukemia Virus Type 1-Transformed Cells through Induction of BIC Expression

(2011) L. Wang et al.   JOURNAL OF VIROLOGY

Upregulation of the Cell-Cycle Regulator RGC-32 in Epstein-Barr Virus-Immortalized Cells

(2011) Sandra N. Schlick et al.   PLoS One

Transcription factor IRF8 directs a silencing programme for TH17 cell differentiation

(2011) Xinshou Ouyang et al.   Nature Communications

Epstein-Barr Virus Nuclear Antigen 3C Facilitates G1-S Transition by Stabilizing and Enhancing the Function of Cyclin D1

(2011) Abhik Saha et al.   PLoS Pathogens

IRF4 silencing inhibits Hodgkin lymphoma cell proliferation, survival and CCL5 secretion

(2010) Donatella Aldinucci et al.   BRITISH JOURNAL OF HAEMATOLOGY

Regulation of immunity and oncogenesis by the IRF transcription factor family

(2010) David Savitsky et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

EBNA3C Attenuates the Function of p53 through Interaction with Inhibitor of Growth Family Proteins 4 and 5

(2010) A. Saha et al.   JOURNAL OF VIROLOGY

IRF4: Immunity. Malignancy! Therapy?

(2009) A. L. Shaffer et al.   CLINICAL CANCER RESEARCH

Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated Herpesvirus (KSHV) Upregulates Survivin Expression in KSHV-Associated B-Lymphoma Cells and Contributes to Their Proliferation

(2009) J. Lu et al.   JOURNAL OF VIROLOGY

Epstein-Barr Virus Nuclear Antigen 3C Augments Mdm2-Mediated p53 Ubiquitination and Degradation by Deubiquitinating Mdm2

(2009) A. Saha et al.   JOURNAL OF VIROLOGY

Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses

(2009) Ye Zheng et al.   NATURE

Early Events Associated with Infection of Epstein-Barr Virus Infection of Primary B-Cells

(2009) Sabyasachi Halder et al.   PLoS One

Epstein-Barr virus nuclear protein EBNA3C residues critical for maintaining lymphoblastoid cell growth

(2009) S. Maruo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epstein–Barr virus nuclear antigen 3C targets p53 and modulates its transcriptional and apoptotic activities

(2009) Fuming Yi et al.   VIROLOGY

The IRF Family Transcription Factors in Immunity and Oncogenesis

(2008) Tomohiko Tamura et al.   Annual Review of Immunology

IRF-4 functions as a tumor suppressor in early B-cell development

(2008) J. Acquaviva et al.   BLOOD

IRF8 regulates B-cell lineage specification, commitment, and differentiation

(2008) H. Wang et al.   BLOOD

Positive histone marks are associated with active transcription from a methylated ICSBP/IRF8 gene

(2008) Marina Tshuikina et al.   GENE

Interferon Regulatory Factor 4 Is Involved in Epstein-Barr Virus-Mediated Transformation of Human B Lymphocytes

(2008) D. Xu et al.   JOURNAL OF VIROLOGY

Epstein-Barr Virus Nuclear Antigen 3C Interacts with and Enhances the Stability of the c-Myc Oncoprotein

(2008) B. G. Bajaj et al.   JOURNAL OF VIROLOGY

A Role for Interferon Regulatory Factor 4 in Receptor Editing

(2008) S. Pathak et al.   MOLECULAR AND CELLULAR BIOLOGY

TRAF6 and the Three C-Terminal Lysine Sites on IRF7 Are Required for Its Ubiquitination-Mediated Activation by the Tumor Necrosis Factor Receptor Family Member Latent Membrane Protein 1

(2008) S. Ning et al.   MOLECULAR AND CELLULAR BIOLOGY

IRF4 addiction in multiple myeloma

(2008) Arthur L. Shaffer et al.   NATURE