Herpes Simplex Virus Type 1 Single Strand DNA Binding Protein and Helicase/Primase Complex Disable Cellular ATR Signaling

Efficient Herpes Simplex Virus 1 Replication Requires Cellular ATR Pathway Proteins

(2012) K. N. Mohni et al.   JOURNAL OF VIROLOGY

Herpes Simplex Viruses: Mechanisms of DNA Replication

(2012) S. K. Weller et al.   Cold Spring Harbor Perspectives in Biology

The HSV-1 Exonuclease, UL12, Stimulates Recombination by a Single Strand Annealing Mechanism

(2012) April J. Schumacher et al.   PLoS Pathogens

ATR signalling: more than meeting at the fork

(2011) Edward A. Nam et al.   BIOCHEMICAL JOURNAL

Identification and evaluation of a potent novel ATR inhibitor, NU6027, in breast and ovarian cancer cell lines

(2011) A Peasland et al.   BRITISH JOURNAL OF CANCER

Cell cycle-dependent processing of DNA lesions controls localization of Rad9 to sites of genotoxic stress

(2011) Daniël O. Warmerdam et al.   CELL CYCLE

Increased oncolytic efficacy for high-grade gliomas by optimal integration of ionizing radiation into the replicative cycle of HSV-1

(2011) S J Advani et al.   GENE THERAPY

Thr-1989 Phosphorylation Is a Marker of Active Ataxia Telangiectasia-mutated and Rad3-related (ATR) Kinase

(2011) Edward A. Nam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oncolytic Virus-Mediated Manipulation of DNA Damage Responses: Synergy With Chemotherapy in Killing Glioblastoma Stem Cells

(2011) Ryuichi Kanai et al.   JNCI-Journal of the National Cancer Institute

DNA Mismatch Repair Proteins Are Required for Efficient Herpes Simplex Virus 1 Replication

(2011) K. N. Mohni et al.   JOURNAL OF VIROLOGY

ATR Autophosphorylation as a Molecular Switch for Checkpoint Activation

(2011) Shizhou Liu et al.   MOLECULAR CELL

Selective killing of ATM- or p53-deficient cancer cells through inhibition of ATR

(2011) Philip M Reaper et al.   Nature Chemical Biology

A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations

(2011) Luis I Toledo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ATR and ATRIP Are Recruited to Herpes Simplex Virus Type 1 Replication Compartments Even though ATR Signaling Is Disabled

(2010) K. N. Mohni et al.   JOURNAL OF VIROLOGY

Coordinated Leading and Lagging Strand DNA Synthesis by Using the Herpes Simplex Virus 1 Replication Complex and Minicircle DNA Templates

(2010) G. Stengel et al.   JOURNAL OF VIROLOGY

Herpes Simplex Virus Type 1 Helicase-Primase: DNA Binding and Consequent Protein Oligomerization and Primase Activation

(2010) Y. Chen et al.   JOURNAL OF VIROLOGY

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

Adenovirus 12 E4orf6 inhibits ATR activation by promoting TOPBP1 degradation

(2010) A. N. Blackford et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mislocalization of the MRN complex prevents ATR signaling during adenovirus infection

(2009) Christian T Carson et al.   EMBO JOURNAL

Human RPA phosphorylation by ATR stimulates DNA synthesis and prevents ssDNA accumulation during DNA-replication stress

(2009) V. M. Vassin et al.   JOURNAL OF CELL SCIENCE

TopBP1 activates ATR through ATRIP and a PIKK regulatory domain

(2008) D. A. Mordes et al.   GENES & DEVELOPMENT

Cellular Functions of Human RPA1

(2008) Stuart J. Haring et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oligomerization of ICP4 and Rearrangement of Heat Shock Proteins May Be Important for Herpes Simplex Virus Type 1 Prereplicative Site Formation

(2008) C. M. Livingston et al.   JOURNAL OF VIROLOGY

ATR: an essential regulator of genome integrity

(2008) Karlene A. Cimprich et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Rad9 plays an important role in DNA mismatch repair through physical interaction with MLH1

(2008) W. He et al.   NUCLEIC ACIDS RESEARCH