Sub-Inhibitory Concentrations of Human α-defensin Potentiate Neutralizing Antibodies against HIV-1 gp41 Pre-Hairpin Intermediates in the Presence of Serum

Multifaceted Mechanisms of HIV-1 Entry Inhibition by Human α-Defensin

(2012) Lusine H. Demirkhanyan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIV Entry and Envelope Glycoprotein-mediated Fusion

(2012) Robert Blumenthal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Visualization of retrovirus uptake and delivery into acidic endosomes

(2011) Kosuke Miyauchi et al.   BIOCHEMICAL JOURNAL

Binding Interactions between Soluble HIV Envelope Glycoproteins and Quaternary-Structure-Specific Monoclonal Antibodies PG9 and PG16

(2011) T. M. Davenport et al.   JOURNAL OF VIROLOGY

Direct Antibody Access to the HIV-1 Membrane-Proximal External Region Positively Correlates with Neutralization Sensitivity

(2011) B. K. Chakrabarti et al.   JOURNAL OF VIROLOGY

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

(2011) Jason S. McLellan et al.   NATURE

Inhibition of HIV-1 endocytosis allows lipid mixing at the plasma membrane, but not complete fusion

(2011) Michelle de la Vega et al.   Retrovirology

Imaging Single Retrovirus Entry through Alternative Receptor Isoforms and Intermediates of Virus-Endosome Fusion

(2011) Naveen K. Jha et al.   PLoS Pathogens

Nonneutralizing HIV-1 gp41 Envelope Cluster II Human Monoclonal Antibodies Show Polyreactivity for Binding to Phospholipids and Protein Autoantigens

(2010) S. M. Dennison et al.   JOURNAL OF VIROLOGY

Crystal Structure of PG16 and Chimeric Dissection with Somatically Related PG9: Structure-Function Analysis of Two Quaternary-Specific Antibodies That Effectively Neutralize HIV-1

(2010) M. Pancera et al.   JOURNAL OF VIROLOGY

Distinct conformational states of HIV-1 gp41 are recognized by neutralizing and non-neutralizing antibodies

(2010) Gary Frey et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The effect of sCD4 on the binding and accessibility of HIV-1 gp41 MPER epitopes to human monoclonal antibodies

(2010) Kristina K. Peachman et al.   VIROLOGY

Crystal Structure and Size-Dependent Neutralization Properties of HK20, a Human Monoclonal Antibody Binding to the Highly Conserved Heptad Repeat 1 of gp41

(2010) Charles Sabin et al.   PLoS Pathogens

Oligomer-Specific Conformations of the Human Immunodeficiency Virus (HIV-1) gp41 Envelope Glycoprotein Ectodomain Recognized by Human Monoclonal Antibodies

(2009) Wen Yuan et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

HIV Enters Cells via Endocytosis and Dynamin-Dependent Fusion with Endosomes

(2009) Kosuke Miyauchi et al.   CELL

Through the Looking Glass, Mechanistic Insights from Enantiomeric Human Defensins

(2009) Gang Wei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rapid Dissociation of HIV-1 from Cultured Cells Severely Limits Infectivity Assays, Causes the Inactivation Ascribed to Entry Inhibitors, and Masks the Inherently High Level of Infectivity of Virions

(2009) E. J. Platt et al.   JOURNAL OF VIROLOGY

Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target

(2009) L. M. Walker et al.   SCIENCE

Early Steps of HIV-1 Fusion Define the Sensitivity to Inhibitory Peptides That Block 6-Helix Bundle Formation

(2009) Kosuke Miyauchi et al.   PLoS Pathogens

Sequestering of the Prehairpin Intermediate of gp41 by Peptide N36Mut(e,g) Potentiates the Human Immunodeficiency Virus Type 1 Neutralizing Activity of Monoclonal Antibodies Directed against the N-Terminal Helical Repeat of gp41

(2008) E. Gustchina et al.   JOURNAL OF VIROLOGY

Human domain antibodies to conserved sterically restricted regions on gp120 as exceptionally potent cross-reactive HIV-1 neutralizers

(2008) W. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A fusion-intermediate state of HIV-1 gp41 targeted by broadly neutralizing antibodies

(2008) G. Frey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of the steric defense of the HIV-1 gp41 N-trimer region

(2008) Debra M. Eckert et al.   PROTEIN SCIENCE

Common principles and intermediates of viral protein-mediated fusion: the HIV-1 paradigm

(2008) Gregory B Melikyan   Retrovirology

Antibody elicited against the gp41 N-heptad repeat (NHR) coiled-coil can neutralize HIV-1 with modest potency but non-neutralizing antibodies also bind to NHR mimetics

(2008) Josh D. Nelson et al.   VIROLOGY