Human Tetherin Exerts Strong Selection Pressure on the HIV-1 Group N Vpu Protein

Vpu-Deficient HIV Strains Stimulate Innate Immune Signaling Responses in Target Cells

(2012) Brian P. Doehle et al.   JOURNAL OF VIROLOGY

Vpu Mediates Depletion of Interferon Regulatory Factor 3 during HIV Infection by a Lysosome-Dependent Mechanism

(2012) Brian P. Doehle et al.   JOURNAL OF VIROLOGY

A Cytoplasmic Tail Determinant in HIV-1 Vpu Mediates Targeting of Tetherin for Endosomal Degradation and Counteracts Interferon-Induced Restriction

(2012) Tonya Kueck et al.   PLoS Pathogens

Evidence for the innate immune response as a correlate of protection in human immunodeficiency virus (HIV)-1 highly exposed seronegative subjects (HESN)

(2011) C. Tomescu et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Analysis of the human immunodeficiency virus type 1 M group Vpu domains involved in antagonizing tetherin

(2011) S. J. Petit et al.   JOURNAL OF GENERAL VIROLOGY

Separable Determinants of Subcellular Localization and Interaction Account for the Inability of Group O HIV-1 Vpu To Counteract Tetherin

(2011) R. Vigan et al.   JOURNAL OF VIROLOGY

HIV-1 group N: travelling beyond Cameroon

(2011) Constance Delaugerre et al.   LANCET

β-TrCP is dispensable for Vpu's ability to overcome the CD317/Tetherin-imposed restriction to HIV-1 release

(2011) Hanna-Mari Tervo et al.   Retrovirology

HIV-1 Group P is unable to antagonize human tetherin by Vpu, Env or Nef

(2011) Daniel Sauter et al.   Retrovirology

Lack of adaptation to human tetherin in HIV-1 Group O and P

(2011) Su Jung Yang et al.   Retrovirology

HIV-1 Vpu Blocks Recycling and Biosynthetic Transport of the Intrinsic Immunity Factor CD317/Tetherin To Overcome the Virion Release Restriction

(2011) S. Schmidt et al.   mBio

Four New HIV-1 Group N Isolates from Cameroon: Prevalence Continues to Be Low

(2010) Ana Vallari et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Inhibition of lipid antigen presentation in dendritic cells by HIV-1 Vpu interference with CD1d recycling from endosomal compartments

(2010) M. Moll et al.   BLOOD

Tetherin: Holding On and Letting Go

(2010) Daniel Sauter et al.   CELL

Structural Basis of HIV-1 Tethering to Membranes by the BST-2/Tetherin Ectodomain

(2010) Andreas Hinz et al.   Cell Host & Microbe

Degranulation of Natural Killer Cells Following Interaction with HIV-1-Infected Cells Is Hindered by Downmodulation of NTB-A by Vpu

(2010) Ankur H. Shah et al.   Cell Host & Microbe

Immune Evasion and Counteraction of Restriction Factors by HIV-1 and Other Primate Lentiviruses

(2010) Frank Kirchhoff   Cell Host & Microbe

Dual-Color Click Beetle Luciferase Heteroprotein Fragment Complementation Assays

(2010) Victor Villalobos et al.   CHEMISTRY & BIOLOGY

Confirmation of Putative HIV-1 Group P in Cameroon

(2010) A. Vallari et al.   JOURNAL OF VIROLOGY

Identification of Amino Acids in the Human Tetherin Transmembrane Domain Responsible for HIV-1 Vpu Interaction and Susceptibility

(2010) T. Kobayashi et al.   JOURNAL OF VIROLOGY

Determinants of Tetherin Antagonism in the Transmembrane Domain of the Human Immunodeficiency Virus Type 1 Vpu Protein

(2010) R. Vigan et al.   JOURNAL OF VIROLOGY

Ancient Adaptive Evolution of Tetherin Shaped the Functions of Vpu and Nef in Human Immunodeficiency Virus and Primate Lentiviruses

(2010) E. S. Lim et al.   JOURNAL OF VIROLOGY

HIV-1 Vpu targets cell surface markers CD4 and BST-2 through distinct mechanisms

(2010) Amy Andrew et al.   MOLECULAR ASPECTS OF MEDICINE

The evolution of HIV-1 and the origin of AIDS

(2010) P. M. Sharp et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Vpu serine 52 dependent counteraction of tetherin is required for HIV-1 replication in macrophages, but not in ex vivo human lymphoid tissue

(2010) Michael Schindler et al.   Retrovirology

Anti-tetherin activities in Vpu-expressing primate lentiviruses

(2010) Su Yang et al.   Retrovirology

New Algorithms and Methods to Estimate Maximum-Likelihood Phylogenies: Assessing the Performance of PhyML 3.0

(2010) Stéphane Guindon et al.   SYSTEMATIC BIOLOGY

BST-2/tetherin: a new component of the innate immune response to enveloped viruses

(2010) David T. Evans et al.   TRENDS IN MICROBIOLOGY

Antagonism of Tetherin Restriction of HIV-1 Release by Vpu Involves Binding and Sequestration of the Restriction Factor in a Perinuclear Compartment

(2010) Mathieu Dubé et al.   PLoS Pathogens

Tetherin Inhibits HIV-1 Release by Directly Tethering Virions to Cells

(2009) David Perez-Caballero et al.   CELL

Nef Proteins from Simian Immunodeficiency Viruses Are Tetherin Antagonists

(2009) Fengwen Zhang et al.   Cell Host & Microbe

A Tail of Tetherin: How Pandemic HIV-1 Conquered the World

(2009) Ravindra K. Gupta et al.   Cell Host & Microbe

Tetherin-Driven Adaptation of Vpu and Nef Function and the Evolution of Pandemic and Nonpandemic HIV-1 Strains

(2009) Daniel Sauter et al.   Cell Host & Microbe

Vpu Directs the Degradation of the Human Immunodeficiency Virus Restriction Factor BST-2/Tetherin via a  TrCP-Dependent Mechanism

(2009) J. L. Douglas et al.   JOURNAL OF VIROLOGY

A new human immunodeficiency virus derived from gorillas

(2009) Jean-Christophe Plantier et al.   NATURE MEDICINE

Mutation of a Single Residue Renders Human Tetherin Resistant to HIV-1 Vpu-Mediated Depletion

(2009) Ravindra K. Gupta et al.   PLoS Pathogens

HIV-1 Vpu Neutralizes the Antiviral Factor Tetherin/BST-2 by Binding It and Directing Its Beta-TrCP2-Dependent Degradation

(2009) Bastien Mangeat et al.   PLoS Pathogens

Species-Specific Activity of HIV-1 Vpu and Positive Selection of Tetherin Transmembrane Domain Variants

(2009) Matthew W. McNatt et al.   PLoS Pathogens

Vpu Antagonizes BST-2–Mediated Restriction of HIV-1 Release via β-TrCP and Endo-Lysosomal Trafficking

(2009) Richard S. Mitchell et al.   PLoS Pathogens

Species-Specific Activity of SIV Nef and HIV-1 Vpu in Overcoming Restriction by Tetherin/BST2

(2009) Bin Jia et al.   PLoS Pathogens

HIV-1 Accessory Proteins—Ensuring Viral Survival in a Hostile Environment

(2008) Michael H. Malim et al.   Cell Host & Microbe

The Interferon-Induced Protein BST-2 Restricts HIV-1 Release and Is Downregulated from the Cell Surface by the Viral Vpu Protein

(2008) Nanette Van Damme et al.   Cell Host & Microbe

Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu

(2008) Stuart J. D. Neil et al.   NATURE