Pharmacological characterization of crotamine effects on mice hind limb paralysis employing both ex vivo and in vivo assays: Insights into the involvement of voltage-gated ion channels in the crotamine action on skeletal muscles

Crotamine induces browning of adipose tissue and increases energy expenditure in mice

(2018) Marcelo P. Marinovic et al.   Scientific Reports

Antivenomics as a tool to improve the neutralizing capacity of the crotalic antivenom: a study with crotamine

(2017) Ricardo Teixeira-Araújo et al.   JOURNAL OF VENOMOUS ANIMALS AND TOXINS INCLUDING TROPICAL DISEASES

MicroRNA cluster miR-17-92 regulates multiple functionally related voltage-gated potassium channels in chronic neuropathic pain

(2017) Atsushi Sakai et al.   Nature Communications

Characterization of the Antinociceptive Mechanisms of Khat Extract (Catha edulis) in Mice

(2017) Elham A. Afify et al.   Frontiers in Neurology

Neuromuscular electrical stimulation prevents skeletal muscle dysfunction in adjuvant-induced arthritis rat

(2017) Koichi Himori et al.   PLoS One

Veratridine produces distinct calcium response profiles in mouse Dorsal Root Ganglia neurons

(2017) Zainab A. Mohammed et al.   Scientific Reports

MPP+-Lesioned Mice: an Experimental Model of Motor, Emotional, Memory/Learning, and Striatal Neurochemical Dysfunctions

(2016) Mauricio P. Cunha et al.   MOLECULAR NEUROBIOLOGY

Activation of KCNQ channels located on the skeletal muscle membrane by retigabine and its influence on the maximal muscle force in rat muscle strips

(2016) P. Zagorchev et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Potassium channels in neuropathic pain

(2016) Jérôme Busserolles et al.   PAIN

Age modifies respiratory complex I and protein homeostasis in a muscle type-specific manner

(2015) Shane E. Kruse et al.   AGING CELL

Role played by NaV 1.7 channels on thin-fiber muscle afferents in transmitting the exercise pressor reflex

(2015) Audrey J. Stone et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Involvement of potassium channels in the progression of cancer to a more malignant phenotype

(2015) Nuria Comes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Targeting ion channels for cancer therapy by repurposing the approved drugs

(2015) Vijay Pralhad Kale et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Targeting a mitochondrial potassium channel to fight cancer

(2015) Luigi Leanza et al.   CELL CALCIUM

Piezo2 is the principal mechanotransduction channel for proprioception

(2015) Seung-Hyun Woo et al.   NATURE NEUROSCIENCE

Targeting potassium channels in cancer

(2014) Xi Huang et al.   JOURNAL OF CELL BIOLOGY

Contractile abnormalities of mouse muscles expressing hyperkalemic periodic paralysis mutant NaV1.4 channels do not correlate with Na+ influx or channel content

(2014) Brooke Lucas et al.   PHYSIOLOGICAL GENOMICS

Tetrodotoxin: Chemistry, Toxicity, Source, Distribution and Detection

(2014) Vaishali Bane et al.   Toxins

Effective contractile response to voltage-gated Na+ channels revealed by a channel activator

(2013) W.-S. Vanessa Ho et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

New index of pain triggered by spinal activation of voltage-dependent sodium channels

(2013) Ryugo Enomoto et al.   Journal of Anesthesia

Synergistically acting PLA2: Peptide hemorrhagic complex from Daboia russelii venom

(2013) Madhukumar Venkatesh et al.   TOXICON

Unraveling the antifungal activity of a South American rattlesnake toxin crotamine

(2012) Erica S. Yamane et al.   BIOCHIMIE

Sodium Channels as Targets for Volatile Anesthetics

(2012) Karl F. Herold et al.   Frontiers in Pharmacology

Extended-release dalfampridine in the management of multiple-sclerosis-related walking impairment

(2012) Carrie Hersh et al.   Therapeutic Advances in Neurological Disorders

Merging Structural Motifs of Functionalized Amino Acids and α-Aminoamides Results in Novel Anticonvulsant Compounds with Significant Effects on Slow and Fast Inactivation of Voltage-Gated Sodium Channels and in the Treatment of Neuropathic Pain

(2011) Yuying Wang et al.   ACS Chemical Neuroscience

Crotamine toxicity and efficacy in mouse models of melanoma

(2011) Alexandre Pereira et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Nav1.4 and Nav1.5 are modulated differently during muscle immobilization and contractile phenotype conversion

(2011) Fabrice Rannou et al.   JOURNAL OF APPLIED PHYSIOLOGY

The Natural Cell-Penetrating Peptide Crotamine Targets Tumor Tissue in Vivo and Triggers a Lethal Calcium-Dependent Pathway in Cultured Cells

(2011) Fabio D. Nascimento et al.   MOLECULAR PHARMACEUTICS

Na+currents are required for efficient excitation-contraction coupling in rabbit ventricular myocytes: a possible contribution of neuronal Na+channels

(2010) Natalia S. Torres et al.   JOURNAL OF PHYSIOLOGY-LONDON

Selective reciprocity in antimicrobial activity versus cytotoxicity of hBD-2 and crotamine

(2009) N. Y. Yount et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytotoxic effects of crotamine are mediated through lysosomal membrane permeabilization

(2008) Mirian A.F. Hayashi et al.   TOXICON