Article
Chemistry, Medicinal
Manuel Vilela, Carolina Mengue
Summary: Currently, there is no universally adopted classification system for central serous chorioretinopathy due to unknown aspects related to pathogenesis and clinical spectrum and evolution. The best option may be to aggregate multimodal pieces of information alongside temporal and phenotypic characteristics.
Review
Ophthalmology
Adrian T. T. Fung, Yi Yang, Andrew W. W. Kam
Summary: Central serous chorioretinopathy (CSC) is a common non-surgical retinopathy associated with fluid leakage. The exact cause is not fully understood, but changes in the choroid, sclera, and RPE have been observed. CSC can be divided into acute, chronic, and recurrent subtypes, and recent classifications include simple and complex based on RPE changes. Multimodal imaging is useful in the diagnosis and management of CSC and its complications. Treatment options include laser, medications, intravitreal therapy, and surgery, with argon laser and photodynamic therapy having the strongest evidence.
CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2023)
Article
Multidisciplinary Sciences
Donghyun Jee, Ji Hyun Yoon, Ho Ra, Jin-woo Kwon, Jiwon Baek
Summary: This study successfully predicted the prognosis of central serous chorioretinopathy using multiple optical coherence tomography images and deep convolutional neural networks. The accuracy of prediction was improved by concatenating multiple image sets. These results are valuable for choosing the optimal treatment for patients with CSC.
SCIENTIFIC REPORTS
(2022)
Article
Ophthalmology
Mehmet Fatih Karadag
Summary: Our study found that variabilities in 24-h, daytime SBP and DBP were significantly higher in patients with CSCR compared to controls. Multivariate logistic regression models revealed that the VI values for 24-h and daytime SBP and DBP emerged as independent risk factors for developing CSCR. This suggests that increased BPV may be a new risk factor for the development of CSCR.
Article
Computer Science, Information Systems
Syed Ale Hassan, Shahzad Akbar, Habib Ullah Khan
Summary: This study proposes a deep learning-based method for retinal disease detection using OCT and fundus photography. Through multiple experiments, the DenseNet network achieves the best accuracy of 99.78%, sensitivity of 99.6%, specificity of 100%, and F1 score of 99.52% on OCT images. The experimental results demonstrate the effectiveness and efficiency of the proposed model for retinal disease detection and its suitability for clinical applications.
MULTIMEDIA TOOLS AND APPLICATIONS
(2023)
Review
Computer Science, Information Systems
Syed Ale Hassan, Shahzad Akbar, Amjad Rehman, Tanzila Saba, Hoshang Kolivand, Saeed Ali Bahaj
Summary: This review summarizes automatic detection techniques for CSR, including CSR detection methods based on classical imaging technologies and machine/deep learning methods, finding that the latest deep learning classifiers provide accurate, fast, and reliable CSR detection.
Article
Multidisciplinary Sciences
Hyun-Jung Lee, Hyung-Kwan Kim, Bong-Seong Kim, Kyung-Do Han, Chan Soon Park, Tae-Min Rhee, Jun-Bean Park, Heesun Lee, Yong-Jin Kim
Summary: Anti-tuberculosis treatment can interfere with effective anticoagulation. This study investigated the safety and effectiveness of using non-vitamin K antagonist oral anticoagulants (NOACs) and warfarin in patients on anti-tuberculosis treatment. The results showed that NOACs were associated with a lower risk of ischemic stroke compared to warfarin, while there was no significant difference in the risk of major bleeding or death.
SCIENTIFIC REPORTS
(2023)
Article
Multidisciplinary Sciences
Lisa Toto, Rossella D'Aloisio, Chiara De Nicola, Federica Evangelista, Maria Ludovica Ruggeri, Luca Cerino, Maria Beatrice Simonelli, Agbeanda Aharrh-Gnama, Marta Di Nicola, Annamaria Porreca, Rodolfo Mastropasqua
Summary: This study compared anatomical/functional changes after navigated subthreshold pulse laser and oral eplerenone therapy for chronic central serous chorioretinopathy. Both treatments were effective in improving CMT, FSRFT, and BCVA, with a greater absolute variation in the SML group compared to the eplerenone group.
SCIENTIFIC REPORTS
(2022)
Editorial Material
Ophthalmology
Supriya Arora, Baldassarre D. Stea, Russell J. Hamilton, Jay Chhablani
Summary: Low dose radiation can be used in refractory cases of central serous chorioretinopathy (CSCR) to decrease the hyperpermeability of large choroidal vessels.
OPHTHALMOLOGY AND THERAPY
(2022)
Article
Rheumatology
Paul Billoir, Adrien Michon, Luc Darnige
Summary: Antiphospholipid syndrome (APS) is an acquired autoimmune disease characterized by recurrent thrombotic events and pregnancy morbidity, with persistently presence of antiphospholipid antibodies (aPL). This study reports three cases of central serous chorioretinopathy (CSC) associated with APS.
Article
Nanoscience & Nanotechnology
Han Li, Yinan Ding, Jiayan Huang, Yanyan Zhao, Wei Chen, Qiusha Tang, Yanli An, Rong Chen, Chunmei Hu
Summary: In this study, we loaded rifampin (RIF) into exosomes and modified the exosomes with a brain-targeting peptide to improve the blood-brain barrier (BBB) permeability. The results showed that the modified exosomes exhibited high targeting capacity and permeability in vitro and in vivo, and had high anti-tuberculosis activity and biocompatibility, providing hope for an effective treatment of CNS-TB.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2023)
Article
Ophthalmology
K. Sandeep, Kavitha C. Venugopal, Akshatha P. Javagal, Pavana Acharya, S. R. Sreelekshmi, N. Narendra, P. K. Nayana
Summary: This study compared the efficacy of oral propranolol, oral rifampicin, and intravitreal anti-VEGF therapies in the treatment of central serous chorioretinopathy (CSCR). The results showed that oral propranolol and oral rifampicin could be useful and cost-effective treatments for CSCR, while intravitreal anti-VEGF therapy resulted in faster resolution of the condition.
INDIAN JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Ophthalmology
Xiaoyin Zhou, Hisashi Fukuyama, Yoichi Okita, Hiroyuki Kanda, Yuki Yamamoto, Takashi Araki, Fumi Gomi
Summary: This study assessed the autonomic nervous system in patients with central serous chorioretinopathy (CSC) by measuring pupillary responses and heart rate variability (HRV). The results indicated parasympathetic inhibition and sympathetic activation in CSC patients, as well as larger pupil dilation during mental tasks, which could be a potential marker of psychophysiological stress.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2022)
Editorial Material
Dermatology
Nicole Fett, Victoria P. Werth
Summary: Antimalarial prescribers should prescribe dosages carefully and perform regular eye examinations, while eye care specialists play an important role in screening and treatment cessation.
Article
Ophthalmology
Xiaoyin Zhou, Hisashi Fukuyama, Takaaki Sugisawa, Yoichi Okita, Hiroyuki Kanda, Yuki Yamamoto, Takashi Araki, Fumi Gomi
Summary: This study investigated and compared the pupillary response between acute and chronic central serous chorioretinopathy (CSC), as well as different disease categories. The results showed differences in pupillary response between the acute and chronic CSC groups, and the pupillary response was associated with retinal/choroidal architecture.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2023)
Article
Ophthalmology
Andrew Pouw, Rustum Karanjia, Alfredo Sadun
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2017)
Article
Ophthalmology
Philip P. Storey, Hassan A. Aziz, Ghazala A. Datoo O'Keefe, Mark Borchert, Linda A. Lam, Carmen A. Puliafito, Lisa C. Olmos de Koo
BRITISH JOURNAL OF OPHTHALMOLOGY
(2018)
Article
Ophthalmology
Stanislao Rizzo, Pierre-Olivier Barale, Sarah Ayello-Scheer, Robert G. Devenyi, Marie-Noelle Delyfer, Jean-Francois Korobelnik, Aleksandra Rachitskaya, Alex Yuan, K. Thiran Jayasundera, David N. Zacks, James T. Handa, Sandra R. Montezuma, Dara Koozekanani, Paulo E. Stanga, Lyndon Da Cruz, Peter Walter, Albert J. Augustin, Marzio Chizzolini, Lisa C. Olmos de Koo, Allen C. Ho, Bernd Kirchhof, Paul Hahn, Lejla Vajzovic, Raymond Iezzi, David Gaucher, J. Fernando Arevalo, Ninel Z. Gregori, Salvatore Grisanti, Emin Ozmert, Young Hee Yoon, Gregg T. Kokame, Jennifer Lim, Peter Szurman, Eugene de Juan, Flavio A. Rezende, Joel Salzmann, Gisbert Richard, Suber S. Huang, Francesco Merlini, Uday Patel, Cynthia Cruz, Robert J. Greenberg, Sally Justus, Laura Cinelli, Mark S. Humayun
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
(2020)
Article
Ophthalmology
Stanislao Rizzo, Pierre-Olivier Barale, Sarah Ayello-Scheer, Robert G. Devenyi, Marie Noelle Delyfer, Jean-Francois Korobelnik, Aleksandra Rachitskaya, Alex Yuan, K. Thiran Jayasundera, David N. Zacks, James T. Handa, Sandra R. Montezuma, Dara Koozekanani, Paulo Stanga, Lyndon da Cruz, Peter Walter, Albert J. Augustin, Lisa C. Olmos de Koo, Allen C. Ho, Bernd Kirchhof, Paul Hahn, Lejla Vajzovic, Raymond Iezzi, David Gaucher, J. Fernando Arevalo, Ninel Z. Gregori, Peter Wiedemann, Emin Ozmert, Jennifer Lim, Flavio A. Rezende, Suber S. Huang, Francesco Merlini, Uday Patel, Robert J. Greenberg, Sally Justus, Daniela Bacherini, Laura Cinelli, Mark S. Humayun
BRITISH JOURNAL OF OPHTHALMOLOGY
(2020)
Article
Ophthalmology
Gautam Vangipuram, Aaron Y. Lee, Kasra A. Rezaei, Lisa C. Olmos De Koo, Yewlin E. Chee, Jennifer R. Chao, Catherine Egan, Cecilia S. Lee
JOURNAL OF OPHTHALMOLOGY
(2019)
Article
Ophthalmology
Jocelyn Lam, Ian Luttrell, Leona Ding, Kasra Rezaei, Jennifer R. Chao, Yewlin Chee, Lisa C. Olmos De Koo, Joanne C. Wen
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2019)
Article
Ophthalmology
Cecilia S. Lee, Bryan Hong, Sundeep K. Kasi, Christopher Aderman, Katherine E. Talcott, Murtaza K. Adam, Bryan Yue, Lakshmi Akileswaran, Kenji Nakamichi, Yue Wu, Kasra A. Rezaei, Lisa C. Olmos de Koo, Yewlin E. Chee, Aaron Y. Lee, Sunir J. Garg, Russell N. Van Gelder
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2020)
Review
Endocrinology & Metabolism
Debarshi Mustafi, Steven S. Saraf, Qing Shang, Lisa C. Olmos de Koo
DIABETES RESEARCH AND CLINICAL PRACTICE
(2020)
Article
Education, Scientific Disciplines
Benjamin Young, Andrew Pouw, Amanda Redfern, Fei Cai, Jessica Chow
Summary: The study demonstrates the implementation of a novel medical education podcast series for ophthalmology students and residents, showing feasibility, sustainability, and acceptance of this learning platform.
JOURNAL OF SURGICAL EDUCATION
(2021)
Editorial Material
Ophthalmology
Laura C. Huang, John P. Kelly, Michelle T. Cabrera, Lisa C. Olmos de Koo, Avery H. Weiss, Erin P. Herlihy
Article
Multidisciplinary Sciences
Yining Dai, Hao Zhou, Qinqin Zhang, Zhongdi Chu, Lisa C. Olmos de Koo, Jennifer R. Chao, Kasra A. Rezaei, Steven S. Saraf, Ruikang K. Wang
Article
Ophthalmology
Mark P. Breazzano, Archana A. Nair, J. Fernando Arevalo, Mark R. Barakat, Audina M. Berrocal, Jonathan S. Chang, Andrew Chen, Dean Eliott, Sunir J. Garg, Quraish Ghadiali, Dan Gong, Dilraj S. Grewal, James T. Handa, Matthew Henderson, Yannek I. Leiderman, Theodore Leng, Amar Mannina, Thomas A. Mendel, Debarshi Mustafi, Lisa C. Olmos de Koo, Shriji N. Patel, Tapan P. Patel, Jonathan Prenner, Paige Richards, Rishi P. Singh, Charles C. Wykoff, Nicolas A. Yannuzzi, Hannah Yu, Yasha S. Modi, Stanley Chang
Summary: This study found a significant nationwide decrease in urgent or emergent vitreoretinal surgical procedures during the COVID-19 pandemic, which lasted for a period independent of region, practice setting, and state-level stay-at-home orders. The decline suggests a need for ophthalmology practices to prioritize availability for such critical procedures until the reasons behind the decrease are fully understood.
JAMA OPHTHALMOLOGY
(2021)
Review
Cell Biology
Andrew E. Pouw, Mark A. Greiner, Razek G. Coussa, Chunhua Jiao, Ian C. Han, Jessica M. Skeie, John H. Fingert, Robert F. Mullins, Elliott H. Sohn
Summary: This review highlights the crucial role of the extracellular matrix (ECM) in maintaining normal physiologic functions and regulating processes such as angiogenesis and intraocular pressure in the eye. Various pathways and key factors related to ECM in the eye are discussed, along with alterations contributing to disease states like wound healing, diabetes-related complications, and age-related macular degeneration.
Review
Surgery
Amy Yuan, Dong Yang, Lisa Olmos de Koo
Summary: Surgical trends in repairing macular holes have focused on techniques such as inverted ILM flap and other variations to improve closure rates, as well as utilizing acellular scaffolds and other surgical innovations to address core concepts of pathology in macular hole formation.
CURRENT SURGERY REPORTS
(2021)
Article
Ophthalmology
Andrew E. Pouw, Fei Cai, Amanda J. Redfern, Jessica Chow, Benjamin K. Young
Summary: This study characterized the listenership and perceived educational impact of the ophthalmic podcast Eyes for Ears through a survey and analysis of download data. The podcast was downloaded over 422,000 times from January 10, 2019 to September 2, 2021, averaging about 4442 downloads per episode. The surveyed eye care professionals, including medical students, residents, fellows, clinicians, and technicians, reported positive experiences with the podcast, finding it useful for their education and well-being.
CLINICAL OPHTHALMOLOGY
(2023)
