Combined TLR7/8 and TLR9 Ligands Potentiate the Activity of a Schistosoma japonicum DNA Vaccine

Partial Regulatory T Cell Depletion Prior to Schistosomiasis Vaccination Does Not Enhance the Protection

(2012) Xuefeng Wang et al.   PLoS One

Activation of dendritic cells via TLR7 reduces Foxp3 expression and suppressive function in induced Tregs

(2011) Daniela Hackl et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Targeting of Toll-like receptors: a decade of progress in combating infectious diseases

(2011) Mona Hedayat et al.   LANCET INFECTIOUS DISEASES

Regulatory and Activated T Cells in Human Schistosoma haematobium Infections

(2011) Norman Nausch et al.   PLoS One

Transient depletion of regulatory T cells in transgenic mice reactivates virus-specific CD8+ T cells and reduces chronic retroviral set points

(2011) K. K. Dietze et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vaccine adjuvant activity of 3M-052: An imidazoquinoline designed for local activity without systemic cytokine induction

(2011) Dmitri Smirnov et al.   VACCINE

The pharmacokinetics of Toll-like receptor agonists and the impact on the immune system

(2011) Abbi L Engel et al.   Expert Review of Clinical Pharmacology

The potential use of Toll-like receptor agonists to restore the dysfunctional immunity induced by hepatitis C virus

(2010) Mohamed L. Salem et al.   CELLULAR IMMUNOLOGY

Use of defined TLR ligands as adjuvants within human vaccines

(2010) Malcolm S. Duthie et al.   IMMUNOLOGICAL REVIEWS

An ISCOM vaccine combined with a TLR9 agonist breaks immune evasion mediated by regulatory T cells in an orthotopic model of pancreatic carcinoma

(2010) Collin Jacobs et al.   INTERNATIONAL JOURNAL OF CANCER

Protective effects of Sm-p80 in the presence of resiquimod as an adjuvant against challenge infection with Schistosoma mansoni in mice

(2010) Gul Ahmad et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Using 3 TLR ligands as a combination adjuvant induces qualitative changes in T cell responses needed for antiviral protection in mice

(2010) Qing Zhu et al.   JOURNAL OF CLINICAL INVESTIGATION

Blockade of CCL1 Inhibits T Regulatory Cell Suppressive Function Enhancing Tumor Immunity without Affecting T Effector Responses

(2010) D. B. Hoelzinger et al.   JOURNAL OF IMMUNOLOGY

Applying TLR Synergy in Immunotherapy: Implications in Cutaneous Leishmaniasis

(2010) V. S. Raman et al.   JOURNAL OF IMMUNOLOGY

The nature and combination of subunits used in epitope-based Schistosoma japonicum vaccine formulations affect their efficacy

(2010) Xuefeng Wang et al.   Parasites & Vectors

Effect of CD4+CD25+ regulatory T cells on the immune evasion of Schistosoma japonicum

(2010) Chun-lian Tang et al.   PARASITOLOGY RESEARCH

TLR-based immune adjuvants

(2010) Folkert Steinhagen et al.   VACCINE

Schistosoma mansoni Stomatin Like Protein-2 Is Located in the Tegument and Induces Partial Protection against Challenge Infection

(2010) Leonardo P. Farias et al.   PLoS Neglected Tropical Diseases

Surveillance of Antigen-Presenting Cells by CD4+CD25+ Regulatory T Cells in Autoimmunity

(2009) Sébastien André et al.   AMERICAN JOURNAL OF PATHOLOGY

CD4+CD25+Treg induction by an HSP60-derived peptide SJMHE1 fromSchistosoma japonicumis TLR2 dependent

(2009) Xuefeng Wang et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Molecular orchestration of differentiation and function of regulatory T cells

(2009) L.-F. Lu et al.   GENES & DEVELOPMENT

Interleukin-10: new perspectives on an old cytokine

(2009) David M. Mosser et al.   IMMUNOLOGICAL REVIEWS

Regulatory T cells overturned: the effectors fight back

(2009) Lucy S. K. Walker   IMMUNOLOGY

Regulatory T cells: how do they suppress immune responses?

(2009) S. Sakaguchi et al.   INTERNATIONAL IMMUNOLOGY

Generation in vivo of peptide-specific cytotoxic T cells and presence of regulatory T cells during vaccination with hTERT (class I and II) peptide-pulsed DCs

(2009) Mark M Aloysius et al.   Journal of Translational Medicine

Toward the Elimination of Schistosomiasis

(2009) Charles H. King   NEW ENGLAND JOURNAL OF MEDICINE

The Schistosomiasis Control Initiative (SCI): rationale, development and implementation from 2002–2008

(2009) A. FENWICK et al.   PARASITOLOGY

Current chemotherapy arsenal for schistosomiasis mansoni: alternatives and challenges

(2009) Rashad Abdul-Ghani et al.   PARASITOLOGY RESEARCH

Current Status of Vaccines for Schistosomiasis

(2008) D. P. McManus et al.   CLINICAL MICROBIOLOGY REVIEWS

Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis

(2008) Michael J Doenhoff et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Immunization with a Toll-Like Receptor 7 and/or 8 Agonist Vaccine Adjuvant Increases Protective Immunity against Leishmania major in BALB/c Mice

(2008) W.-W. Zhang et al.   INFECTION AND IMMUNITY

Helminth infections: the great neglected tropical diseases

(2008) Peter J. Hotez et al.   JOURNAL OF CLINICAL INVESTIGATION

TLR ligand suppression or enhancement of Treg cells? A double-edged sword in immunity to tumours

(2008) H Conroy et al.   ONCOGENE

Toll-like receptor ligands synergize through distinct dendritic cell pathways to induce T cell responses: Implications for vaccines

(2008) Q. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhancement by IL-18 of the protective effect of a Schistosoma japonicum 26kDa GST plasmid DNA vaccine in mice

(2008) Feng Wei et al.   VACCINE

Schistosoma mansoni Tegument Protein Sm29 Is Able to Induce a Th1-Type of Immune Response and Protection against Parasite Infection

(2008) Fernanda C. Cardoso et al.   PLoS Neglected Tropical Diseases

Macrophage activation by endogenous danger signals

(2007) X Zhang et al.   JOURNAL OF PATHOLOGY

T cell epitope-based peptide-DNA dual vaccine induces protective immunity against Schistosoma japonicum infection in C57BL/6J mice

(2007) Lei Zhang et al.   MICROBES AND INFECTION