Selective Inhibitors of Protozoan Protein N-myristoyltransferases as Starting Points for Tropical Disease Medicinal Chemistry Programs

Global malaria mortality between 1980 and 2010: a systematic analysis

(2012) Christopher JL Murray et al.   LANCET

A fluorescence-based assay for N-myristoyltransferase activity

(2011) Victor Goncalves et al.   ANALYTICAL BIOCHEMISTRY

Leishmaniasis impact and treatment access

(2011) M. den Boer et al.   CLINICAL MICROBIOLOGY AND INFECTION

Drug to Genome to Drug: Discovery of New Antiplasmodial Compounds

(2011) Terence B. Beghyn et al.   JOURNAL OF MEDICINAL CHEMISTRY

Trypanosoma brucei Glycogen Synthase Kinase-3, A Target for Anti-Trypanosomal Drug Development: A Public-Private Partnership to Identify Novel Leads

(2011) Richard O. Oduor et al.   PLoS Neglected Tropical Diseases

N-myristoyltransferase inhibitors as new leads to treat sleeping sickness

(2010) Julie A. Frearson et al.   NATURE

Developments in the treatment of visceral leishmaniasis

(2009) Margriet Leontine den Boer et al.   EXPERT OPINION ON EMERGING DRUGS

Enhanced HTS Hit Selection via a Local Hit Rate Analysis

(2009) Bruce A. Posner et al.   Journal of Chemical Information and Modeling

N-Myristoyltransferase from Leishmania donovani: Structural and Functional Characterisation of a Potential Drug Target for Visceral Leishmaniasis

(2009) James A. Brannigan et al.   JOURNAL OF MOLECULAR BIOLOGY

Myristoyl-CoA:protein N-myristoyltransferase depletion in trypanosomes causes avirulence and endocytic defects

(2009) Helen P. Price et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

N-Myristoyltransferase: a Prospective Drug Target for Protozoan Parasites

(2008) Paul W. Bowyer et al.   ChemMedChem

Identification and Characterization of Small Molecule Inhibitors ofPlasmodium falciparumDihydroorotate Dehydrogenase

(2008) Vishal Patel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY