Review
Environmental Sciences
Adane Sewhunegn Molla, Patrick Tang, Willy Sher, Dawit Nega Bekele
Summary: This study reviewed research on chemicals of concern in construction and demolition waste fine residues, finding heavy metals and toxic gases in landfills, as well as organic chemicals such as PAHs, PCBs, and flame retardants. Health implications include carcinogenicity, organ damage, and neurological disorders. Despite environmental and health issues, C&DW fine residues are often disposed in landfills without adequate management strategies.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2021)
Review
Cardiac & Cardiovascular Systems
G. L. E. Monnink, C. Stijnis, O. M. van Delden, R. Spijker, M. P. Grobusch
Summary: Limited prospective studies, especially RCTs, are available. In the four included studies, only conventional surgery is directly compared to percutaneous techniques. From the available data, percutaneous treatment of hydatid cysts is non-inferior to open surgery in terms of recurrence. In terms of complications and length of hospital stay, outcomes favour percutaneous therapy.
CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY
(2021)
Review
Nutrition & Dietetics
Monika Mielus, Dorota Sands, Marek Woynarowski
Summary: This study aimed to summarize the effects of nutritional interventions on anthropometric measures in patients with cystic fibrosis. The results supported personalized nutritional plans, high-fat, high-calorie diets, and enteric tube feeding as beneficial, while supplementation of probiotics, lipids, docosahexaenoic, glutathione, or antioxidant-enriched multivitamin showed little effect on anthropometric measures.
Review
Medicine, General & Internal
Mathieu N. N. Suleiman, Valeska Brueckl, Joerg Fechner, Ann-Sophie Kaemmerer, Florian Wilk, Michael Weyand, Frank Harig
Summary: This study reviewed cases of cardiac surgery patients with systemic mastocytosis and emphasized the importance of careful preoperative planning and coordination between cardiac surgeons, anesthesiologists, and hemato-oncological specialists.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Infectious Diseases
Aliakbar Vaisi-Raygani, Masoud Mohammadi, Rostam Jalali, Nader Salari, Melika Hosseinian-Far
Summary: This study conducted a systematic review and meta-analysis to determine the prevalence of cystic echinococcosis in slaughtered livestock in Iran. The results showed a relatively high prevalence of the disease in the region, with the prevalence increasing with larger sample sizes and over time. Health policy makers should consider these findings and implement appropriate interventions to address this issue.
BMC INFECTIOUS DISEASES
(2021)
Review
Endocrinology & Metabolism
Shenzhong Jiang, Zhaojian Wang, Yan You, Renzhi Wang, Xinjie Bao
Summary: This article presents a 31-year-old female with intermittent headaches and oligomenorrhea of over 10 years' duration. Surgical resection revealed a mature cystic teratoma instead of the initially suspected Rathke's cleft cyst. The patient has had a good recovery with no headache or teratoma recurrence at the most recent follow-up approximately 1 year later.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Review
Parasitology
Adriano Casulli, Alessandro Massolo, Urmas Saarma, Gerald Umhang, Federica Santolamazza, Azzurra Santoro
Summary: This study fills a knowledge gap by providing a quantitative measure of molecularly identified species and genotypes causing human cystic echinococcosis. The study identifies geographical hotspots of different Echinococcus granulosus species causing the disease and highlights data gaps.
PARASITES & VECTORS
(2022)
Review
Medicine, General & Internal
Francesca J. New, Sally J. Deverill, Bhaskar K. Somani
Summary: The outcomes of percutaneous nephrostomy (PCN) in patients with advanced malignancies show an average survival time of 5.6 months, influenced by cancer type, stage, and previous treatment. Patients with advanced malignancies who require PCN tend to have a survival rate under 12 months and spend a significant portion of this time in the hospital. Decisions on nephrostomy must balance survival and quality of life, and should be discussed with the patient.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Pediatrics
Giorgia Contini, Simone Frediani, Valerio Pardi, Francesca Diomedi-Camassei, Alessandro Inserra
Summary: Cystic dysplasia of the rete testis (CDRT) is a rare cause of testicular masses in children and is often associated with other genitourinary anomalies. This study reports a case of a 9-year-old boy and performs a literature review to further understand this pathology.
FRONTIERS IN PEDIATRICS
(2022)
Review
Oncology
So-Young Park, Jung-Won Lim
Summary: This study systematically reviewed the evidence from randomized controlled trials (RCTs) of cognitive behavioral therapy (CBT) designed to reduce fear of cancer recurrence (FCR) among breast cancer survivors (BCSs). The findings suggest that face-to-face interventions lasting at least 1 month were more effective and better complied with the CONSORT 2010 criteria than brief online or telephone interventions. Overall, most interventions appeared to be effective.
Article
Gastroenterology & Hepatology
Suat Eren, Sonay Aydin, Mecit Kantarci, Volkan Kizilgoz, Akin Levent, Duzgun Can Senbil, Okan Akhan
Summary: This study aimed to characterize HAE patients who were treated percutaneously, their outcomes, and the major technical features of percutaneous treatment in HAE. The results showed that percutaneous drainage of cyst contents and/or biliary channels using a minimally invasive technique is a very beneficial treatment method that improves the quality of life for patients who are unable to undergo surgery.
WORLD JOURNAL OF GASTROINTESTINAL SURGERY
(2023)
Review
Oncology
Sagar H. Chandrashekhar, Simi Ismail, Pavan K. Jonnada, Baiju Senadhipan, Monish Karunakaran, Savio George Barreto
Summary: Meta-analysis of 15 studies found that extended distal pancreatectomy (EDP) is associated with higher incidence of postoperative pancreatic fistula, major complications, re-explorations, mortality and readmissions. However, pooled analysis showed that EDP is noninferior to standard distal pancreatectomy in terms of 3- and 5-year survival. Conclusion: EDP is feasible and may offer equivalent survival in highly selected patients but carries a higher risk of perioperative morbidity and mortality.
Review
Virology
Cesar Fernandez-de-las-Penas, Kin Israel Notarte, Princess Juneire Peligro, Jacqueline Veronica Velasco, Miguel Joaquin Ocampo, Brandon Michael Henry, Lars Arendt-Nielsen, Juan Torres-Macho, Gustavo Plaza-Manzano
Summary: This study compared the prevalence of long-COVID symptoms according to relevant SARS-CoV-2 variants in COVID-19 survivors, finding that individuals infected with the historical variant are more likely to develop long-COVID symptomatology, while patients infected with the Omicron variant have the lowest prevalence of long-COVID symptoms.
Review
Medicine, General & Internal
Ou Xu, Jan Hartmann, Yi-Da Tang, Joao Dias
Summary: Dual antiplatelet therapy is crucial for preventing ischemic events after acute coronary syndrome. Thromboelastography shows promise in assessing therapy response and guiding individualized treatment. This systematic review evaluates the utility of thromboelastography in ACS/PCI in East Asia, finding that it may be better than other techniques in detecting low treatment response and guiding therapy escalation.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Oncology
Juntao Ran, Guofeng Qu, Xiaohua Chen, Da Zhao
Summary: Primary tracheal adenoid cystic carcinoma (TACC) is rare and originates from the minor salivary gland, leading to delayed presentation and varied therapeutic effects. The most common presenting symptoms are dyspnoea, cough, and shortness of breath. Surgery alone and surgery with postoperative radiotherapy are predominant treatment modalities, both showing promising results in terms of disease control and long-term survival rate in TACC patients.
RADIATION ONCOLOGY
(2021)
Letter
Infectious Diseases
Francesca Tamarozzi, Adriano Casulli
JOURNAL OF INFECTION
(2020)
Letter
Public, Environmental & Occupational Health
Tommaso Manciulli, Maria Teresa Giordani, Raffaella Lissandrin, Enrico Brunetti, Francesca Tamarozzi
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
(2020)
Editorial Material
Public, Environmental & Occupational Health
Dora Buonfrate, Francesca Tamarozzi, Federico Gobbi
JOURNAL OF TRAVEL MEDICINE
(2020)
Article
Immunology
Linda Petrone, Werner C. Albrich, Francesca Tamarozzi, Manuel Frischknecht, Maria Angeles Gomez-Morales, Antonella Teggi, Matthias Hoffmann, Delia Goletti
PARASITE IMMUNOLOGY
(2020)
Editorial Material
Parasitology
Adriano Casulli, Mar Siles-Lucas, Carmen Michaela Cretu, Kamena Vutova, Okan Akhan, Gulay Vural, Arantxa Cortes Ruiz, Enrico Brunetti, Francesca Tamarozzi
TRENDS IN PARASITOLOGY
(2020)
Article
Parasitology
Patrizia Rossi, Francesca Tamarozzi, Fabio Galati, Okan Akhan, Carmen Michaela Cretu, Kamenna Vutova, Mar Siles-Lucas, Enrico Brunetti, Adriano Casulli
PARASITES & VECTORS
(2020)
Review
Parasitology
Francesca Tamarozzi, Peter Deplazes, Adriano Casulli
TRENDS IN PARASITOLOGY
(2020)
Article
Infectious Diseases
Federico Gobbi, Dora Buonfrate, Michel Boussinesq, Cedric B. Chesnais, Sebastien D. Pion, Ronaldo Silva, Lucia Moro, Paola Rodariid, Francesca Tamarozzi, Marco Biamonte, Zeno Bisoffi
PLOS NEGLECTED TROPICAL DISEASES
(2020)
Article
Medicine, General & Internal
Francesca Tamarozzi, Silvia Stefania Longoni, Ambra Vola, Monica Degani, Stefano Tais, Eleonora Rizzi, Marco Prato, Salvatore Scarso, Ronaldo Silva, Enrico Brunetti, Zeno Bisoffi, Francesca Perandin
Summary: The study evaluated the performance of nine commercial serological tests for diagnosing echinococcosis and found that using WB-LDBIO alone or as a third test after other non-WB tests yielded the best results. Reading results with stringent criteria may be a sensible approach.
Article
Biochemistry & Molecular Biology
Emma C. Thomson, Laura E. Rosen, James G. Shepherd, Roberto Spreafico, Ana da Silva Filipe, Jason A. Wojcechowskyj, Chris Davis, Luca Piccoli, David J. Pascall, Josh Dillen, Spyros Lytras, Nadine Czudnochowski, Rajiv Shah, Marcel Meury, Natasha Jesudason, Anna De Marco, Kathy Li, Jessica Bassi, Aine O'Toole, Dora Pinto, Rachel M. Colquhoun, Katja Culap, Ben Jackson, Fabrizia Zatta, Andrew Rambaut, Stefano Jaconi, Vattipally B. Sreenu, Jay Nix, Ivy Zhang, Ruth F. Jarrett, William G. Glass, Martina Beltramello, Kyriaki Nomikou, Matteo Pizzuto, Lily Tong, Elisabetta Cameroni, Tristan Croll, Natasha Johnson, Julia Di Iulio, Arthur Wickenhagen, Alessandro Ceschi, Aoife M. Harbison, Daniel Mair, Paolo Ferrari, Katherine Smollett, Federica Sallusto, Stephen Carmichael, Christian Garzoni, Jenna Nichols, Massimo Galli, Joseph Hughes, Agostino Riva, Antonia Ho, Marco Schiuma, Malcolm G. Semple, Peter J. M. Openshaw, Elisa Fadda, J. Kenneth Baillie, John D. Chodera, Suzannah J. Rihn, Samantha J. Lycett, Herbert W. Virgin, Amalio Telenti, Davide Corti, David L. Robertson, Gyorgy Snell
Summary: SARS-CoV-2 virus can mutate and evade immunity, with mutations like N439K conferring resistance against neutralizing monoclonal antibodies and enhancing binding affinity to hACE2 receptor. Despite similar in vitro replication fitness and clinical outcomes compared to wild type, N439K mutation highlights the importance of ongoing molecular surveillance for guiding vaccine and therapeutic development and usage.
Article
Multidisciplinary Sciences
Yiwei Chen, Kai Xu, Luca Piccoli, Mathilde Foglierini, Joshua Tan, Wenjie Jin, Jason Gorman, Yaroslav Tsybovsky, Baoshan Zhang, Boubacar Traore, Chiara Silacci-Fregni, Claudia Daubenberger, Peter D. Crompton, Roger Geiger, Federica Sallusto, Peter D. Kwong, Antonio Lanzavecchia
Summary: This study demonstrates that Plasmodium falciparum RIFINs can bind to LILRB1 through D3, and inserting receptor domains into the VH-CH1 elbow can generate novel antibodies, as shown by a naturally selected example.
Article
Multidisciplinary Sciences
Maura Garofalo, Luca Piccoli, Margherita Romeo, Maria Monica Barzago, Sara Ravasio, Mathilde Foglierini, Milos Matkovic, Jacopo Sgrignani, Raoul De Gasparo, Marco Prunotto, Luca Varani, Luisa Diomede, Olivier Michielin, Antonio Lanzavecchia, Andrea Cavalli
Summary: Systemic light chain amyloidosis (AL) is caused by the production of toxic light chains and can be fatal, yet effective treatments are often not possible due to delayed diagnosis. Here the authors show that a machine learning platform analyzing light chain somatic mutations allows the prediction of light chain toxicity to serve as a possible tool for early diagnosis of AL.
NATURE COMMUNICATIONS
(2021)
Article
Clinical Neurology
Florian Ingelfinger, Michael Kramer, Mirjam Lutz, Corinne C. Widmer, Luca Piccoli, Stefanie Kreutmair, Tobias Wertheimer, Mark Woodhall, Patrick Waters, Federica Sallusto, Antonio Lanzavecchia, Sarah Mundt, Burkhard Becher, Bettina Schreiner
Summary: This study suggests that myasthenia gravis (MG) may be associated with hematologic malignancies such as chronic lymphocytic leukemia (CLL). It is unclear whether the leukemic B cells are directly responsible for the autoimmune response in patients with MG and CLL. However, treatment with the anti-CD20 therapy obinutuzumab has shown potential in effectively treating AChR(+) MG.
NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION
(2023)
Article
Multidisciplinary Sciences
Amin Addetia, Luca Piccoli, James Brett Case, Young-Jun Park, Martina Beltramello, Barbara Guarino, Ha Dang, Guilherme Dias de Melo, Dora Pinto, Kaitlin Sprouse, Suzanne M. Scheaffer, Jessica Bassi, Chiara Silacci-Fregni, Francesco Muoio, Marco Dini, Lucia Vincenzetti, Rima Acosta, Daisy Johnson, Sambhavi Subramanian, Christian Saliba, Martina Giurdanella, Gloria Lombardo, Giada Leoni, Katja Culap, Carley Mcalister, Anushka Rajesh, Exequiel Dellota, Jiayi Zhou, Nisar Farhat, Dana Bohan, Julia Noack, Alex Chen, Florian A. Lempp, Joel Quispe, Lauriane Kergoat, Florence Larrous, Elisabetta Cameroni, Bradley Whitener, Olivier Giannini, Pietro Cippa, Alessandro Ceschi, Paolo Ferrari, Alessandra Franzetti-Pellanda, Maira Biggiogero, Christian Garzoni, Stephanie Zappi, Luca Bernasconi, Min Jeong Kim, Laura E. Rosen, Gretja Schnell, Nadine Czudnochowski, Fabio Benigni, Nicholas Franko, Jennifer K. Logue, Courtney Yoshiyama, Cameron Stewart, Helen Chu, Herve Bourhy, Michael A. Schmid, Lisa A. Purcell, Gyorgy Snell, Antonio Lanzavecchia, Michael S. Diamond, Davide Corti, David Veesler
Summary: The recently emerged BQ.1.1 and XBB.1.5 variants of SARS-CoV-2 have a higher affinity for the host ACE2 receptor and more efficiently promote fusion with host cell membranes compared to earlier Omicron variants. Although the neutralizing activity is reduced, vaccine-induced human plasma antibodies still cross-react with and trigger effector functions against current Omicron variants, providing a mechanism of protection against disease.
Article
Medicine, Research & Experimental
Marco Pirazzini, Alessandro Grinzato, Davide Corti, Sonia Barbieri, Oneda Leka, Francesca Vallese, Marika Tonellato, Chiara Silacci-Fregni, Luca Piccoli, Eaazhisai Kandiah, Giampietro Schiavo, Giuseppe Zanotti, Antonio Lanzavecchia, Cesare Montecucco
Summary: The study identified two highly neutralizing tetanus neurotoxin-specific monoclonal antibodies that interfere with the binding and translocation of the neurotoxin into neurons. They were found to be effective in preventing and treating tetanus in mice, suggesting their potential for prophylactic and therapeutic use in human tetanus, and are ready for clinical trials.
JOURNAL OF CLINICAL INVESTIGATION
(2021)
