Article
Health Care Sciences & Services
Tsheten Tsheten, Kefyalew Addis Alene, Angela Cadavid Restrepo, Matthew Kelly, Colleen Lau, Archie C. A. Clements, Darren J. Gray, Chona Daga, Vanessa Joy Mapalo, Fe Esperanza Espino, Kinley Wangdi
Summary: The study in the Philippines identified sociodemographic and environmental factors driving soil-transmitted helminth (STH) transmission, predicting high-risk areas in the country. Higher prevalence of Ascaris lumbricoides and Trichuris trichiura was found in Visayas Island, while hookworm prevalence was highest in Mindanao Island. Male gender, temperature, and rainfall were associated with increased STH risk, while normalized difference vegetation index and soil pH were negatively correlated with transmission. The identified high-risk areas can be targeted for deworming and health education activities to reduce the burden of STH infections.
LANCET REGIONAL HEALTH-WESTERN PACIFIC
(2024)
Article
Parasitology
Nur-Amirah Hassan, Autchariya Thodsapol, Yvonne Ai Lian Lim, Wan Yusoff Wan Sulaiman, Siti Farah Norasyikeen Sidi Omar, Kamontam Umsakul, Romano Ngui
Summary: This study conducted in Malaysia identified Ascaris lumbricoides as the predominant STH species infecting indigenous communities, contradicting past studies by showing Ancylostoma duodenale to be more abundant than Necator americanus. The results highlight the importance of including socioeconomic improvement and health education programs in the management and prevention of STH infections in public health strategies.
PARASITOLOGY INTERNATIONAL
(2021)
Article
Multidisciplinary Sciences
Mian Zi Tee, Soo Ching Lee, Yi Xian Er, Nan Jiun Yap, Romano Ngui, Alice V. Easton, Vinnie Wei Yin Siow, Kee Seong Ng, Christopher Chiong Meng Boey, Kek Heng Chua, Ken Cadwell, P'ng Loke, Yvonne Ai Lian Lim
Summary: STH infections are highly prevalent among indigenous communities in Malaysia. Children and teenagers, poor sanitation and hygiene behavior were determinants for STH infections. Triple dose albendazole is found to be efficacious against Ascaris lumbricoides and hookworm infections but has moderate curative effect with high ERR against T. trichiura.
Article
Infectious Diseases
Ladina Keller, Sophie Welsche, Chandni Patel, Somphou Sayasone, Said M. Ali, Shaali M. Ame, Jan Hattendorf, Eveline Huerlimann, Jennifer Keiser
Summary: The study conducted in Laos and Pemba Island showed that the long-term outcomes of ivermectin-albendazole were superior to albendazole in terms of cure rates and egg reduction rates against Trichuris trichiura infections at both 6 and 12 months. However, the reinfection rates were considerably higher in Pemba Island compared to Laos.
PLOS NEGLECTED TROPICAL DISEASES
(2021)
Article
Infectious Diseases
Eindra Aung, Kay Thwe Han, Catherine A. Gordon, Nyein Nyein Hlaing, Moe Moe Aye, Myo Win Htun, Khin Thet Wai, Su Mon Myat, Thida Lay Thwe, Aung Tun, Kinley Wangdi, Yuesheng Li, Gail M. Williams, Archie C. A. Clements, Susana Vaz Nery, Donald P. McManus, Darren J. Gray
Summary: This study aimed to examine the status of soil-transmitted helminth (STH) infections in Myanmar and found a high prevalence of STH despite bi-annual deworming. The results prompted the expansion of the national STH control program to include all school-aged children, and the need for improving sanitation and hygiene measures.
INFECTIOUS DISEASES OF POVERTY
(2022)
Article
Health Care Sciences & Services
Alemayehu Assefa, Berhanu Erko, Svein Gunnar Gundersen, Girmay Medhin, Nega Berhe
Summary: The study revealed a high prevalence of infections in the study area, with Schistosoma mansoni and asymptomatic malaria being prominent. Undernutrition and anemia were identified as significant public health issues, with a significant association found between infection status and undernutrition and anemia.
JOURNAL OF MULTIDISCIPLINARY HEALTHCARE
(2021)
Article
Multidisciplinary Sciences
Franco Zacharia, Valeria Silvestri, Vivian E. Mushi, George Ogweno, Twilumba Makene, Lwidiko Mhamilawa, David Zadock Munisi
Summary: This study aimed to determine the prevalence and risk factors associated with ongoing transmission of STH infection among adults in Muleba District, Tanzania. The study found that farming, not wearing shoes in general, and not wearing shoes during garden activities were significantly associated with STH infection. The study recommends implementing integrated management to address practices contributing to ongoing transmission.
Article
Multidisciplinary Sciences
Franco Zacharia, Valeria Silvestri, Vivian Mushi, George Ogweno, Twilumba Makene, Lwidiko E. Mhamilawa
Summary: This study aimed to investigate the prevalence and risk factors of STH infection among adults in Muleba District, Tanzania. The results showed a prevalence of 9.1% for STH infection, and factors associated with STH infection included farming, not wearing shoes, and engaging in gardening activities.
Article
Public, Environmental & Occupational Health
James L. A. Webb
Summary: The Rockefeller Foundation, through partnerships with overseas governments, aimed to combat hookworm disease and improve feces disposal practices in India and British Malaya in 1913. However, despite efforts, the projects faced challenges and ultimately ended without significant intervention against syndemic anemia.
SOCIAL SCIENCE & MEDICINE
(2022)
Article
Infectious Diseases
Charity Wiafe Akenten, Felix Weinreich, Ellis Kobina Paintsil, John Amuasi, Dennis Fosu, Ulrike Loderstadt, Juergen May, Hagen Frickmann, Denise Dekker
Summary: Despite eradication programs, helminth infections remain a medical issue in Ghana. A retrospective study conducted between 2007 and 2008 in the Ashanti region found a low prevalence of enteric helminth infections in Ghanaian children.
TROPICAL MEDICINE AND INFECTIOUS DISEASE
(2022)
Article
Biotechnology & Applied Microbiology
Yao Hu, Wen Zhou, Chengguang Zhu, Yujie Zhou, Qiang Guo, Xiaoyu Huang, Bina Yang, Biao Ren, Lei Cheng
Summary: Nicotine, a key component of cigarette smoking, can interact with Staphylococcus aureus to synergistically induce peri-implant infections, increasing bone pathology and promoting the expression of key virulence factors. This interaction also leads to the upregulation of RANKL expression, further promoting the development of peri-implant infections, suggesting a potential new target for reducing these infections.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Review
Infectious Diseases
Sarah Lebu, Winnie Kibone, Chimdi C. C. Muoghalu, Stephen Ochaya, Aaron Salzberg, Felix Bongomin, Musa Manga
Summary: Researchers have found that soil-transmitted helminth (STH) infections can affect the host's immune response and the severity of other illnesses. The co-infection of STH with diseases like malaria, HIV, tuberculosis, anemia, neglected tropical diseases, COVID-19, and HPV have both positive and negative effects. Integrated approaches combining drug administration with WASH interventions, hygiene education, community engagement, and vaccines are crucial for controlling and eliminating STH co-infections.
PLOS NEGLECTED TROPICAL DISEASES
(2023)
Article
Infectious Diseases
Adam W. Bartlett, Jose C. Sousa-Figueiredo, Roelofje C. van Goor, Paul Monaghan, Warren Lancaster, Rukaaka Mugizi, Elsa P. Mendes, Susana Vaz Nery, Sergio Lopes
Summary: This study reports the prevalence, intensity and risk factors for schistosomiasis and soil-transmitted helminths (STHs) in Angola. The results show that most municipalities meet the prevalence thresholds for a schistosomiasis preventive chemotherapy program, and STH preventive chemotherapy is recommended for nearly all municipalities in Uige and select municipalities in Huambo and Zaire. The study also highlights the association between ecological zone, ethnicity, and the risk of schistosomiasis and STH infection, suggesting the need for further evaluation and targeted control strategies.
INFECTIOUS DISEASES OF POVERTY
(2022)
Article
Public, Environmental & Occupational Health
Vicente Belizario, John Paul Caesar Robles Delos Trinos, Olivia Sison, Esther Miranda, Victorio Molina, Agnes Cuayzon, Maria Epifania Isiderio, Rodel Delgado
Summary: This study aimed to describe the prevalence and intensity of soil-transmitted helminthiasis (STH) and schistosomiasis, as well as the nutritional status in preschool-age children (PSAC) and school-age children (SAC) in two Haiyan-stricken provinces. The study also investigated the association between STH, Schistosoma japonicum exposure, nutritional status, and sanitation. The findings suggest a persisting high burden of STH in PSAC and SAC, with significant associations between stunting, anemia, and STH in non-ZOD barangays. Strengthening local health systems and promoting intersectoral collaboration are needed for a coordinated response to address STH, undernutrition, and WASH in disaster-stricken areas.
PATHOGENS AND GLOBAL HEALTH
(2021)
Article
Biochemistry & Molecular Biology
Natalia Wronska, Michal Szlaur, Katarzyna Zawadzka, Katarzyna Lisowska
Summary: Currently, there is a need for new antimicrobial drugs due to the excessive use of antibiotics and emerging resistance amongst bacteria. This study found that two triterpenoids and one flavonoid displayed antimicrobial activity and showed potential synergistic effects, enhancing the antimicrobial potential.
Article
Nursing
Jennifer L. Barkin, Laura Beals, Christy C. Bridges, Amara Ezeamama, Marta Serati, Massimiliano Buoli, Amber Erickson, Megan Chapman, Joan R. Bloch
Summary: The study showed that participating in the Visiting Moms program significantly improved postpartum maternal functioning and depression symptoms, indicating that programs aimed at providing enhanced social support can effectively promote mental and emotional well-being among new mothers in the postpartum period.
JOURNAL OF THE AMERICAN PSYCHIATRIC NURSES ASSOCIATION
(2021)
Article
Public, Environmental & Occupational Health
Charles H. King, Sue Binder, Ye Shen, Christopher C. Whalen, Carl H. Campbell, Ryan E. Wiegand, Annette Olsen, William Evan Secor, Susan P. Montgomery, Rosemary Musuva, Pauline N. M. Mwinzi, Pascal Magnussen, Safari Kinung'hi, Gisele N. Andrade, Amara E. Ezeamama, Daniel G. Colley
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
(2020)
Review
Public, Environmental & Occupational Health
Charles H. King, David Bertsch, Gisele N. Andrade, Michael Burnim, Amara E. Ezeamama, Sue Binder, Daniel G. Colley
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
(2020)
Article
Public, Environmental & Occupational Health
Allan K. Nkwata, Xiao Song, Ming Zhang, Amara. E. Ezeamama
Article
Medicine, General & Internal
Amara E. Ezeamama, Alla Sikorskii, Parvathy R. Sankar, Noeline Nakasujja, Michael Ssonko, Norbert E. Kaminski, David Guwatudde, Michael J. Boivin, Bruno Giordani
JOURNAL OF CLINICAL MEDICINE
(2020)
Article
Nursing
Jennifer L. Barkin, Joan Rosen Bloch, Katherine E. R. Smith, Sarah N. Telliard, Analise McGreal, Chris Sikes, Amare Ezeamama, Massimiliano Buoli, Marta Serati, Christy C. Bridges
Summary: The study found mixed results with pregnant women showing both interest and reluctance towards home visiting programs during high-risk pregnancies. Themes of distrust and fear of judgment were present. Women varied in their preferences for home visiting services, including assistance with medical needs, functional tasks, household tasks, and child care.
JOURNAL OF MIDWIFERY & WOMENS HEALTH
(2021)
Article
Environmental Sciences
Allan K. Nkwata, Ming Zhang, Xiao Song, Bruno Giordani, Amara E. Ezeamama
Summary: The study found that discrimination, chronic stress, and low mastery were associated with worse cognition. The persistent cognitive disadvantage for African American individuals compared to White/Other races was only present among adults with high mastery, suggesting that adverse social experiences may counteract the cognitive benefits associated with mastery among African American populations.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Infectious Diseases
A. E. Ezeamama, S. K. Zalwango, A. Sikorskii, R. Tuke, P. M. Musoke, B. Giordani, M. J. Boivin
Summary: The study aimed to quantify the association between in utero/peripartum antiretroviral (IPA) exposure and cognition, executive function (EF), and socioemotional adjustment (SEA) in school-aged Ugandan children. Different types of IPA exposure may have varying effects on cognitive development in children, with adjustments for caregiver sociodemographic and contextual factors based on the study findings.
Article
Clinical Neurology
Valentina Larrivey, Jennifer Neva, Katherine Finn, Alla Sikorskii, Itziar Familiar-Lopez, Valentine Ucheagwu, Amara Ezeamama, Horacio Ruisenor-Escudero, Noeline Nakasujja, Michael Boivin, Bruno Giordani
Summary: The study found that titrated computerized cognitive rehabilitation training (CCRT) showed better improvement in children's working memory, behavior, and executive functioning compared to non-titrated CCRT. The severity of malaria or other factors did not moderate CCRT performance indicators.
CHILD NEUROPSYCHOLOGY
(2022)
Article
Environmental Sciences
Allan K. Nkwata, Ming Zhang, Xiao Song, Bruno Giordani, Amara E. Ezeamama
Summary: This study investigated the relationship between toxic stress, resiliency-promoting factors, and incident dementia in American adults. The results showed that education level and race were associated with the risk of dementia. Toxic stress may override the cognitive benefits of resiliency-promoting factors, particularly in cases of discrimination or racial inequality.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Environmental Sciences
Jorem Emmillian Awadu, Alla Sikorskii, Sarah Zalwango, Audrey Coventry, Bruno Giordani, Amara E. Ezeamama
Summary: This study examined the potential impact of in utero/peripartum antiretroviral (IPA) exposure on the likelihood of developmental disorders such as ADHD, ASD, and FI. The results showed that overall, IPA exposure during the peripartum period did not have a significant adverse effect on the probability of developmental disorders in children. However, exposure to SdNVP + AZT + 3TC was associated with higher probability of developmental disorders and functional impairment in children aged 6-18 years.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Nutrition & Dietetics
Jorem E. Awadu, Bruno Giordani, Alla Sikorskii, Catherine Abbo, Jenifer I. Fenton, Sarah Zalwango, Amara Esther Ezeamama
Summary: The study tested the hypothesis that vitamin D deficiency is associated with a higher probability of developmental disorders in children with perinatal HIV infection. The results showed that vitamin D deficiency was positively associated with the probability scores of autism, ADHD, emotional behavioral disorder, and functional impairment, and this relationship was dependent on developmental stage.
Article
Medicine, General & Internal
Jorem E. E. Awadu, Sarah K. K. Zalwango, Alla Sikorskii, Bruno Giordani, Michael J. J. Bovin, Philippa M. M. Musoke, Amara E. E. Ezeamama
Summary: This study investigated the growth differences between children with perinatally acquired HIV infection and children HIV exposed but uninfected, and found that children who received antiretroviral treatment showed worse growth than those who did not. This suggests that antiretroviral treatment during the peripartum period can improve the height-for-age of HIV-exposed children.
Article
Nursing
Kaitlyn Barrow, Analise McGreal, Dillon LiVecche, Susan Van Cleve, Chris Sikes, Massimiliano Buoli, Marta Serati, Christy C. Bridges, Amara Ezeamama, Jennifer L. Barkin
Summary: This study aimed to explore barriers and advantages of screening for postpartum depression in the pediatric setting, providers' knowledge of mental health supports in the community, and commonly observed mental health issues in new mothers. The results showed low compliance with screening, with main barriers including lack of time, training, and difficulties in accessing the mother's medical records.
JOURNAL OF THE AMERICAN PSYCHIATRIC NURSES ASSOCIATION
(2022)
Article
Pediatrics
Jane N. Mutanga, Simon Mutembo, Amara E. Ezeamama, Robert C. Fubisha, Derrick Sialondwe, Brenda Simuchembu, Macwani Mutukwa, Jelita Chinyonga, Philip E. Thuma, Christopher C. Whalen
JOURNAL OF TROPICAL PEDIATRICS
(2020)