Sp6 and Sp8 Transcription Factors Control AER Formation and Dorsal-Ventral Patterning in Limb Development

Clinical, genetic, and molecular aspects of split-hand/foot malformation: An update

(2013) Fiorella Gurrieri et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Decoupling the function of Hox and Shh in developing limb reveals multiple inputs of Hox genes on limb growth

(2013) R. Sheth et al.   DEVELOPMENT

Evidence that the limb bud ectoderm is required for survival of the underlying mesoderm

(2013) Marian Fernandez-Teran et al.   DEVELOPMENTAL BIOLOGY

An Integrated Holo-Enhancer Unit Defines Tissue and Gene Specificity of the Fgf8 Regulatory Landscape

(2013) Mirna Marinić et al.   DEVELOPMENTAL CELL

Novel homozygous mutations in the WNT10B gene underlying autosomal recessive split hand/foot malformation in three consanguineous families

(2013) Abdul Aziz et al.   GENE

Delineating a Conserved Genetic Cassette Promoting Outgrowth of Body Appendages

(2013) Congxing Lin et al.   PLoS Genetics

Bmp2, Bmp4 and Bmp7 Are Co-Required in the Mouse AER for Normal Digit Patterning but Not Limb Outgrowth

(2012) Kyung-Suk Choi et al.   PLoS One

A Conserved Pbx-Wnt-p63-Irf6 Regulatory Module Controls Face Morphogenesis by Promoting Epithelial Apoptosis

(2011) Elisabetta Ferretti et al.   DEVELOPMENTAL CELL

A Symphony of Regulations Centered onp63to Control Development of Ectoderm-Derived Structures

(2011) Luisa Guerrini et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Chromosomal Mapping and Candidate Gene Discovery of Chicken Developmental Mutants and Genome-Wide Variation Analysis of MHC Congenics

(2011) Elizabeth A. Robb et al.   JOURNAL OF HEREDITY

Identification of a novelDLX5mutation in a family with autosomal recessive split hand and foot malformation

(2011) Hanan E Shamseldin et al.   JOURNAL OF MEDICAL GENETICS

Homozygous nonsense mutation in WNT10B and sporadic split-hand/foot malformation (SHFM) with autosomal recessive inheritance

(2010) Ariane Blattner et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Split foot and developmental retardation associated with a deletion of three microsatellite markers in 7q21.2-q22.1

(2010) Jean-Christophe Marinoni et al.   CLINICAL GENETICS

Genome-Wide Profiling of p63 DNA–Binding Sites Identifies an Element that Regulates Gene Expression during Limb Development in the 7q21 SHFM1 Locus

(2010) Evelyn N. Kouwenhoven et al.   PLoS Genetics

In the limb AER Bmp2 and Bmp4 are required for dorsal–ventral patterning and interdigital cell death but not limb outgrowth

(2009) Danielle M. Maatouk et al.   DEVELOPMENTAL BIOLOGY

Role of Epiprofin, a zinc-finger transcription factor, in limb development

(2009) Ana Talamillo et al.   DEVELOPMENTAL BIOLOGY

Regulation of Dlx5 and Dlx6 gene expression by p63 is involved in EEC and SHFM congenital limb defects

(2008) N. Lo Iacono et al.   DEVELOPMENT

Genetic mosaic analysis reveals FGF receptor 2 function in terminal end buds during mammary gland branching morphogenesis

(2008) Pengfei Lu et al.   DEVELOPMENTAL BIOLOGY

The incomplete inactivation ofFgf8 in the limb ectoderm affects the morphogenesis of the anterior autopod through BMP-mediated cell death

(2008) Irene Delgado et al.   DEVELOPMENTAL DYNAMICS

Homozygous WNT10b mutation and complex inheritance in Split-Hand/Foot Malformation

(2008) Sibel Aylin Ugur et al.   HUMAN MOLECULAR GENETICS

The Apical Ectodermal Ridge: morphological aspects and signaling pathways

(2008) Marian Fernandez-Teran et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Characterization of mouse Dactylaplasia mutations: a model for human ectrodactyly SHFM3

(2008) Marc Friedli et al.   MAMMALIAN GENOME

Genetic evidence that FGFs have an instructive role in limb proximal–distal patterning

(2008) Francesca V. Mariani et al.   NATURE

FGF signaling regulates mesenchymal differentiation and skeletal patterning along the limb bud proximodistal axis

(2007) K. Yu et al.   DEVELOPMENT