MMS Exposure Promotes Increased MtDNA Mutagenesis in the Presence of Replication-Defective Disease-Associated DNA Polymerase γ Variants
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
MMS Exposure Promotes Increased MtDNA Mutagenesis in the Presence of Replication-Defective Disease-Associated DNA Polymerase γ Variants
Authors
Keywords
-
Journal
PLoS Genetics
Volume 10, Issue 10, Pages e1004748
Publisher
Public Library of Science (PLoS)
Online
2014-10-24
DOI
10.1371/journal.pgen.1004748
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The Exonuclease Activity of the Yeast Mitochondrial DNA Polymerase Suppresses Mitochondrial DNA Deletions Between Short Direct Repeats in Saccharomyces cerevisiae
- (2013) J. D. Stumpf et al. GENETICS
- Clinical and Molecular Features of POLG-Related Mitochondrial Disease
- (2013) J. D. Stumpf et al. Cold Spring Harbor Perspectives in Biology
- Oxidants and not alkylating agents induce rapid mtDNA loss and mitochondrial dysfunction
- (2012) Amy M. Furda et al. DNA REPAIR
- Clustered Mutations in Yeast and in Human Cancers Can Arise from Damaged Long Single-Strand DNA Regions
- (2012) Steven A. Roberts et al. MOLECULAR CELL
- Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice
- (2011) A. Safdar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitochondrial DNA replication and disease: insights from DNA polymerase γ mutations
- (2010) Jeffrey D. Stumpf et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- A single-strand specific lesion drives MMS-induced hyper-mutability at a double-strand break in yeast
- (2010) Yong Yang et al. DNA REPAIR
- mip1 containing mutations associated with mitochondrial disease causes mutagenesis and depletion of mtDNA in Saccharomyces cerevisiae
- (2010) J. D. Stumpf et al. HUMAN MOLECULAR GENETICS
- A cluster of pathogenic mutations in the 3′–5′ exonuclease domain of DNA polymerase gamma defines a novel module coupling DNA synthesis and degradation
- (2010) Karolina Szczepanowska et al. HUMAN MOLECULAR GENETICS
- In vivo analysis of mtDNA replication defects in yeast
- (2010) Enrico Baruffini et al. METHODS
- Structural Insight into Processive Human Mitochondrial DNA Synthesis and Disease-Related Polymerase Mutations
- (2009) Young-Sam Lee et al. CELL
- Evidence for a role of FEN1 in maintaining mitochondrial DNA integrity
- (2009) Lidza Kalifa et al. DNA REPAIR
- Requirement of theSaccharomyces cerevisiae APN1gene for the repair of mitochondrial DNA alkylation damage
- (2009) Karina Acevedo-Torres et al. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
- Evidence That Msh1p Plays Multiple Roles in Mitochondrial Base Excision Repair
- (2009) L. Pogorzala et al. GENETICS
- Disease Mutations in the Human Mitochondrial DNA Polymerase Thumb Subdomain Impart Severe Defects in Mitochondrial DNA Replication
- (2009) Rajesh Kasiviswanathan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- De novo mutation in POLG leads to haplotype insufficiency and Alpers syndrome
- (2009) Sherine S.L. Chan et al. MITOCHONDRION
- DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice
- (2008) Marc Vermulst et al. NATURE GENETICS
- Hypermutability of Damaged Single-Strand DNA Formed at Double-Strand Breaks and Uncapped Telomeres in Yeast Saccharomyces cerevisiae
- (2008) Yong Yang et al. PLoS Genetics
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now