Genetic and Functional Studies Implicate Synaptic Overgrowth and Ring Gland cAMP/PKA Signaling Defects in the Drosophila melanogaster Neurofibromatosis-1 Growth Deficiency

Coordination of organ growth: principles and outstanding questions from the world of insects

(2013) D.S. Andersen et al.   TRENDS IN CELL BIOLOGY

Jelly bellytrans-synaptic signaling to anaplastic lymphoma kinase regulates neurotransmission strength and synapse architecture

(2012) Jeffrey Rohrbough et al.   Developmental Neurobiology

A shared molecular mechanism underlies the human rasopathies Legius syndrome and Neurofibromatosis-1

(2012) I. B. Stowe et al.   GENES & DEVELOPMENT

A neuropeptide signaling pathway regulates synaptic growth inDrosophila

(2012) Xu Chen et al.   JOURNAL OF CELL BIOLOGY

Height Assessments in Children With Neurofibromatosis Type 1

(2012) Elizabeth A. Soucy et al.   JOURNAL OF CHILD NEUROLOGY

Neurofibromin Mediates FAK Signaling in Confining Synapse Growth at Drosophila Neuromuscular Junctions

(2012) P.-I. Tsai et al.   JOURNAL OF NEUROSCIENCE

Mechanisms of Acquired Crizotinib Resistance in ALK-Rearranged Lung Cancers

(2012) R. Katayama et al.   Science Translational Medicine

Integrating Body and Organ Size in Drosophila: Recent Advances and Outstanding Problems

(2012) Christen Kerry Mirth et al.   Frontiers in Endocrinology

Anaplastic Lymphoma Kinase Spares Organ Growth during Nutrient Restriction in Drosophila

(2011) Louise Y. Cheng et al.   CELL

Systematic Discovery of Rab GTPases with Synaptic Functions in Drosophila

(2011) Chih-Chiang Chan et al.   CURRENT BIOLOGY

Coordinating Growth and Maturation — Insights from Drosophila

(2011) Jason M. Tennessen et al.   CURRENT BIOLOGY

Clinical manifestations of mutations in RAS and related intracellular signal transduction factors

(2011) Martin Zenker   CURRENT OPINION IN PEDIATRICS

Proteomic and Functional Genomic Landscape of Receptor Tyrosine Kinase and Ras to Extracellular Signal-Regulated Kinase Signaling

(2011) A. A. Friedman et al.   Science Signaling

The Receptor Tyrosine Kinase Alk Controls Neurofibromin Functions in Drosophila Growth and Learning

(2011) Jean Y. Gouzi et al.   PLoS Genetics

Birth incidence and prevalence of tumor-prone syndromes: Estimates from a UK family genetic register service

(2010) D.G. Evans et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

NF1 Is a Tumor Suppressor in Neuroblastoma that Determines Retinoic Acid Response and Disease Outcome

(2010) Michael Hölzel et al.   CELL

Anterograde Jelly belly ligand to Alk receptor signaling at developing synapses is regulated by Mind the gap

(2010) J. Rohrbough et al.   DEVELOPMENT

Defective cAMP Generation Underlies the Sensitivity of CNS Neurons to Neurofibromatosis-1 Heterozygosity

(2010) J. A. Brown et al.   JOURNAL OF NEUROSCIENCE

ZNF423 Is Critically Required for Retinoic Acid-Induced Differentiation and Is a Marker of Neuroblastoma Outcome

(2009) Sidong Huang et al.   CANCER CELL

A Drosophila Insulin-like Peptide Promotes Growth during Nonfeeding States

(2009) Maija Slaidina et al.   DEVELOPMENTAL CELL

A Fat Body-Derived IGF-like Peptide Regulates Postfeeding Growth in Drosophila

(2009) Naoki Okamoto et al.   DEVELOPMENTAL CELL

HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes

(2009) Simon Bekker-Jensen et al.   NATURE CELL BIOLOGY

Transgenic microRNA inhibition with spatiotemporal specificity in intact organisms

(2009) Carlos M Loya et al.   NATURE METHODS

The Insect Neuropeptide PTTH Activates Receptor Tyrosine Kinase Torso to Initiate Metamorphosis

(2009) K. F. Rewitz et al.   SCIENCE

Genomic Alterations of Anaplastic Lymphoma Kinase May Sensitize Tumors to Anaplastic Lymphoma Kinase Inhibitors

(2008) U. McDermott et al.   CANCER RESEARCH

Dap160/intersectin binds and activates aPKC to regulate cell polarity and cell cycle progression

(2008) C. Chabu et al.   DEVELOPMENT

The invertebrate B0 system transporter, D. melanogaster NAT1, has unique d-amino acid affinity and mediates gut and brain functions

(2008) Melissa M. Miller et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Identification of ALK as a major familial neuroblastoma predisposition gene

(2008) Yaël P. Mossé et al.   NATURE

Activating mutations in ALK provide a therapeutic target in neuroblastoma

(2008) Rani E. George et al.   NATURE

Oncogenic mutations of ALK kinase in neuroblastoma

(2008) Yuyan Chen et al.   NATURE

Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma

(2008) Isabelle Janoueix-Lerosey et al.   NATURE