TATN-1 Mutations Reveal a Novel Role for Tyrosine as a Metabolic Signal That Influences Developmental Decisions and Longevity in Caenorhabditis elegans

TOR Signaling and Rapamycin Influence Longevity by Regulating SKN-1/Nrf and DAF-16/FoxO

(2012) Stacey Robida-Stubbs et al.   Cell Metabolism

Metabolite Profiling Identifies Pathways Associated With Metabolic Risk in Humans

(2012) Susan Cheng et al.   CIRCULATION

Metabolic Signatures of Insulin Resistance in 7,098 Young Adults

(2012) P. Wurtz et al.   DIABETES

Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1

(2012) Mingjian Lu et al.   NATURE MEDICINE

PANTHER in 2013: modeling the evolution of gene function, and other gene attributes, in the context of phylogenetic trees

(2012) Huaiyu Mi et al.   NUCLEIC ACIDS RESEARCH

Cross-Platform Comparison ofCaenorhabditis elegansTissue Extraction Strategies for Comprehensive Metabolome Coverage

(2011) Florian M. Geier et al.   ANALYTICAL CHEMISTRY

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

Specific insulin-like peptides encode sensory information to regulate distinct developmental processes

(2011) A. Cornils et al.   DEVELOPMENT

Integrating genetic and gene expression evidence into genome-wide association analysis of gene sets

(2011) Q. Xiong et al.   GENOME RESEARCH

Quantitative urine amino acid analysis using liquid chromatography tandem mass spectrometry and aTRAQ® reagents

(2011) Patrice K. Held et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB

(2011) William Mair et al.   NATURE

An amino acid profile to predict diabetes?

(2011) Claudia Langenberg et al.   NATURE MEDICINE

Metabolite profiles and the risk of developing diabetes

(2011) Thomas J Wang et al.   NATURE MEDICINE

DAF-12 Regulates a Connected Network of Genes to Ensure Robust Developmental Decisions

(2011) Daniel Hochbaum et al.   PLoS Genetics

PDP-1 Links the TGF-β and IIS Pathways to Regulate Longevity, Development, and Metabolism

(2011) Sri Devi Narasimhan et al.   PLoS Genetics

Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments

(2010) James H Bullard et al.   BMC BIOINFORMATICS

A metabolic signature of long life in Caenorhabditis elegans

(2010) Silke Fuchs et al.   BMC BIOLOGY

EAK-7 Controls Development and Life Span by Regulating Nuclear DAF-16/FoxO Activity

(2010) Hena Alam et al.   Cell Metabolism

Insulin signaling promotes germline proliferation in C. elegans

(2010) D. Michaelson et al.   DEVELOPMENT

Functional divergence of dafachronic acid pathways in the control of C. elegans development and lifespan

(2010) Kathleen J. Dumas et al.   DEVELOPMENTAL BIOLOGY

Down-regulation of tyrosine aminotransferase at a frequently deleted region 16q22 contributes to the pathogenesis of hepatocellular carcinoma

(2010) Li Fu et al.   HEPATOLOGY

skn - 1 -Dependent and -Independent Regulation of aip - 1 Expression following Metabolic Stress in Caenorhabditis elegans

(2010) Annabel A. Ferguson et al.   MOLECULAR AND CELLULAR BIOLOGY

A new DAF-16 isoform regulates longevity

(2010) Eun-Soo Kwon et al.   NATURE

A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance

(2009) Christopher B. Newgard et al.   Cell Metabolism

Regulation of the Longevity Response to Temperature by Thermosensory Neurons in Caenorhabditis elegans

(2009) Seung-Jae Lee et al.   CURRENT BIOLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

The Influence of Bacterial Diet on Fat Storage in C. elegans

(2009) Kyleann K. Brooks et al.   PLoS One

Selection and validation of a set of reliable reference genes for quantitative sod gene expression analysis in C. elegans

(2008) David Hoogewijs et al.   BMC MOLECULAR BIOLOGY

Genetic identification of HSD-1, a conserved steroidogenic enzyme that directs larval development in Caenorhabditis elegans

(2008) D. S. Patel et al.   DEVELOPMENT

Caenorhabditis elegans EAK-3 inhibits dauer arrest via nonautonomous regulation of nuclear DAF-16/FoxO activity

(2008) Yanmei Zhang et al.   DEVELOPMENTAL BIOLOGY

Anabolic function of phenylalanine hydroxylase in Caenorhabditis elegans

(2008) Ana C. Calvo et al.   FASEB JOURNAL

C. elegans dauer formation and the molecular basis of plasticity

(2008) N. Fielenbach et al.   GENES & DEVELOPMENT

Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival

(2008) Patrick Narbonne et al.   NATURE

High concentrations of phenylalanine stimulate peroxisome proliferator-activated receptor γ: Implications for the pathophysiology of phenylketonuria

(2008) Udo Schumacher et al.   NEUROBIOLOGY OF DISEASE

Caenorhabditis elegans HCF-1 Functions in Longevity Maintenance as a DAF-16 Regulator

(2008) Ji Li et al.   PLOS BIOLOGY