Cooperation between RUNX1-ETO9a and Novel Transcriptional Partner KLF6 in Upregulation of Alox5 in Acute Myeloid Leukemia

Attenuation of AML1-ETO cellular dysregulation correlates with increased leukemogenic potential

(2013) R. C. DeKelver et al.   BLOOD

Combined gene expression and DNA occupancy profiling identifies potential therapeutic targets of t(8;21) AML

(2012) M.-C. Lo et al.   BLOOD

PRMT1 interacts with AML1-ETO to promote its transcriptional activation and progenitor cell proliferative potential

(2012) W.-J. Shia et al.   BLOOD

ERG and FLI1 binding sites demarcate targets for aberrant epigenetic regulation by AML1-ETO in acute myeloid leukemia

(2012) J. H. A. Martens et al.   BLOOD

STAT5 Is Crucial to Maintain Leukemic Stem Cells in Acute Myelogenous Leukemias Induced by MOZ-TIF2

(2012) W. F. Tam et al.   CANCER RESEARCH

Hematopoietic Stem Cell Subtypes Expand Differentially during Development and Display Distinct Lymphopoietic Programs

(2012) Claudia Benz et al.   Cell Stem Cell

Current treatment of acute myeloid leukemia

(2012) Gail J. Roboz   CURRENT OPINION IN ONCOLOGY

Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding

(2012) A Ptasinska et al.   LEUKEMIA

LSK Derived LSK– Cells Have a High Apoptotic Rate Related to Survival Regulation of Hematopoietic and Leukemic Stem Cells

(2012) Cong Peng et al.   PLoS One

SON Controls Cell-Cycle Progression by Coordinated Regulation of RNA Splicing

(2011) Eun-Young Ahn et al.   MOLECULAR CELL

The Leukemogenicity of AML1-ETO Is Dependent on Site-Specific Lysine Acetylation

(2011) L. Wang et al.   SCIENCE

Role of Kruppel-like factors in leukocyte development, function, and disease

(2010) Z. Cao et al.   BLOOD

Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials

(2010) D. Grimwade et al.   BLOOD

Role of the Low-Affinity Leukotriene B 4 Receptor BLT2 in VEGF-Induced Angiogenesis

(2009) Geun-Young Kim et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Regulation of gene expression via the core promoter and the basal transcriptional machinery

(2009) Tamar Juven-Gershon et al.   DEVELOPMENTAL BIOLOGY

Loss of the Alox5 gene impairs leukemia stem cells and prevents chronic myeloid leukemia

(2009) Yaoyu Chen et al.   NATURE GENETICS

Ras-induced invasion and metastasis are regulated by a leukotriene B4 receptor BLT2-linked pathway

(2009) E-Y Kim et al.   ONCOGENE

AML1-ETO interacts with Sp1 and antagonizes Sp1 transactivity through RUNT domain

(2008) Hui Wei et al.   FEBS LETTERS

Complementing mutations in core binding factor leukemias: from mouse models to clinical applications

(2008) A M S Müller et al.   ONCOGENE