β-Catenin Is Required for Prostate Development and Cooperates with Pten Loss to Drive Invasive Carcinoma

Wnt signaling though beta-catenin is required for prostate lineage specification

(2012) Brian W. Simons et al.   DEVELOPMENTAL BIOLOGY

The mutational landscape of lethal castration-resistant prostate cancer

(2012) Catherine S. Grasso et al.   NATURE

Germline Mutations inHOXB13and Prostate-Cancer Risk

(2012) Charles M. Ewing et al.   NEW ENGLAND JOURNAL OF MEDICINE

Atlas of Wnt and R-spondin gene expression in the developing male mouse lower urogenital tract

(2011) Vatsal Mehta et al.   DEVELOPMENTAL DYNAMICS

Loss of epithelial oestrogen receptor α inhibits oestrogen-stimulated prostate proliferation and squamous metaplasia via in vivo tissue selective knockout models

(2011) Ming Chen et al.   JOURNAL OF PATHOLOGY

SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression

(2011) Zhihu Ding et al.   NATURE

The changing therapeutic landscape of castration-resistant prostate cancer

(2011) Timothy A. Yap et al.   Nature Reviews Clinical Oncology

TP63 P2 promoter functional analysis identifies β-catenin as a key regulator of ΔNp63 expression

(2011) C Ruptier et al.   ONCOGENE

Exome sequencing identifies a spectrum of mutation frequencies in advanced and lethal prostate cancers

(2011) A. Kumar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrative Genomic Profiling of Human Prostate Cancer

(2010) Barry S. Taylor et al.   CANCER CELL

SOX9 Elevation in the Prostate Promotes Proliferation and Cooperates with PTEN Loss to Drive Tumor Formation

(2010) M. K. Thomsen et al.   CANCER RESEARCH

Bmi-1 Is a Crucial Regulator of Prostate Stem Cell Self-Renewal and Malignant Transformation

(2010) Rita U. Lukacs et al.   Cell Stem Cell

Wnt/β-Catenin activation promotes prostate tumor progression in a mouse model

(2010) X Yu et al.   ONCOGENE

β-catenin expression and claudin expression pattern as prognostic factors of prostatic cancer progression

(2009) Attila M. Szász et al.   BJU INTERNATIONAL

WNT signaling regulates self-renewal and differentiation of prostate cancer cells with stem cell characteristics

(2009) Isabelle Bisson et al.   CELL RESEARCH

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

(2009) Shih-Min A. Huang et al.   NATURE

An Active Role of the ΔN Isoform of p63 in Regulating Basal Keratin Genes K5 and K14 and Directing Epidermal Cell Fate

(2009) Rose-Anne Romano et al.   PLoS One

Crosstalk between the Androgen Receptor and  -Catenin in Castrate-Resistant Prostate Cancer

(2008) G. Wang et al.   CANCER RESEARCH

K-ras and Wnt Signaling Synergize to Accelerate Prostate Tumorigenesis in the Mouse

(2008) H. B. Pearson et al.   CANCER RESEARCH

Sox9 is required for prostate development

(2008) Martin K. Thomsen et al.   DEVELOPMENTAL BIOLOGY

Androgen-induced programs for prostate epithelial growth and invasion arise in embryogenesis and are reactivated in cancer

(2008) E M Schaeffer et al.   ONCOGENE

Regulation of Epithelial Branching Morphogenesis and Cancer Cell Growth of the Prostate by Wnt Signaling

(2008) Bu-Er Wang et al.   PLoS One

Alterations in β‐catenin expression and localization in prostate cancer

(2008) Hayley C. Whitaker et al.   PROSTATE

Activation of β-Catenin in mouse prostate causes HGPIN and continuous prostate growth after castration

(2008) Xiuping Yu et al.   PROSTATE