Limiting of the Innate Immune Response by SF3A-Dependent Control of MyD88 Alternative mRNA Splicing

Mutations affecting mRNA splicing define distinct clinical phenotypes and correlate with patient outcome in myelodysplastic syndromes

(2012) F. Damm et al.   BLOOD

SF3B1 haploinsufficiency leads to formation of ring sideroblasts in myelodysplastic syndromes

(2012) V. Visconte et al.   BLOOD

Mutations in the spliceosome machinery, a novel and ubiquitous pathway in leukemogenesis

(2012) H. Makishima et al.   BLOOD

The zebrafish sf3b1b460mutant reveals differential requirements for the sf3b1 pre-mRNA processing gene during neural crest development

(2012) Min An et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

An Evolutionarily Conserved Innate Immunity Protein Interaction Network

(2012) Lesly De Arras et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of mycelium production and a MAPK-mediated immune response in theC. elegans-Fusariummodel system

(2012) Maged Muhammed et al.   MEDICAL MYCOLOGY

Restraint of inflammatory signaling by interdependent strata of negative regulatory pathways

(2012) Peter J Murray et al.   NATURE IMMUNOLOGY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Dissecting negative regulation of Toll-like receptor signaling

(2012) Takeshi Kondo et al.   TRENDS IN IMMUNOLOGY

Sudemycins, Novel Small Molecule Analogues of FR901464, Induce Alternative Gene Splicing

(2011) Liying Fan et al.   ACS Chemical Biology

SF3B1 mutations are prevalent in myelodysplastic syndromes with ring sideroblasts but do not hold independent prognostic value

(2011) M. M. Patnaik et al.   BLOOD

Clinical significance of SF3B1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms

(2011) L. Malcovati et al.   BLOOD

Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness

(2011) D. Rossi et al.   BLOOD

A Protein Complex Network of Drosophila melanogaster

(2011) K.G. Guruharsha et al.   CELL

MicroRNAs and the resolution phase of inflammation in macrophages

(2011) Muhammad M. Alam et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Reduced fidelity of branch point recognition and alternative splicing induced by the anti-tumor drug spliceostatin A

(2011) A. Corrionero et al.   GENES & DEVELOPMENT

Interaction Domains and Nuclear Targeting Signals in Subunits of the U2 Small Nuclear Ribonucleoprotein Particle-associated Splicing Factor SF3a

(2011) Ching-Jung Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification and Functional Characterization of 14-3-3 in TLR2 Signaling

(2011) Tobias B. Schuster et al.   JOURNAL OF PROTEOME RESEARCH

SF3B1 mutations in myelodysplastic syndromes: clinical associations and prognostic implications

(2011) F Damm et al.   LEUKEMIA

SF3B1, a splicing factor is frequently mutated in refractory anemia with ring sideroblasts

(2011) V Visconte et al.   LEUKEMIA

Frequent pathway mutations of splicing machinery in myelodysplasia

(2011) Kenichi Yoshida et al.   NATURE

Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia

(2011) Víctor Quesada et al.   NATURE GENETICS

SomaticSF3B1Mutation in Myelodysplasia with Ring Sideroblasts

(2011) E. Papaemmanuil et al.   NEW ENGLAND JOURNAL OF MEDICINE

SF3B1and Other Novel Cancer Genes in Chronic Lymphocytic Leukemia

(2011) Lili Wang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

SARM inhibits both TRIF- and MyD88-mediated AP-1 activation

(2010) Jun Peng et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Innate Immune Signaling in the Myelodysplastic Syndromes

(2010) Daniel T. Starczynowski et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Identification of a Novel Human MD-2 Splice Variant That Negatively Regulates Lipopolysaccharide-Induced TLR4 Signaling

(2010) P. Gray et al.   JOURNAL OF IMMUNOLOGY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Spliceostatin A inhibits spliceosome assembly subsequent to prespliceosome formation

(2010) Gabriel A. Roybal et al.   NUCLEIC ACIDS RESEARCH

Contribution of globular death domains and unstructured linkers to MyD88·IRAK-4 heterodimer formation: An explanation for the antagonistic activity of MyD88s

(2009) Elena Mendoza-Barberá et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Spliceosome: Design Principles of a Dynamic RNP Machine

(2009) Markus C. Wahl et al.   CELL

The Modern RNP World of Eukaryotes

(2009) L. J. Collins et al.   JOURNAL OF HEREDITY

Negative regulation of Toll-like receptor signaling pathway

(2009) Jie Wang et al.   MICROBES AND INFECTION

The spliceosome: a self-organized macromolecular machine in the nucleus?

(2009) José Rino et al.   TRENDS IN CELL BIOLOGY

LPS/TLR4 signal transduction pathway

(2008) Yong-Chen Lu et al.   CYTOKINE

Alternative splicing in the NF-κB signaling pathway

(2008) Joshua R. Leeman et al.   GENE

Identification of innate immunity genes and pathways using a comparative genomics approach

(2008) S. Alper et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and Function of the Pre-mRNA Splicing Machine

(2008) Joseph Sperling et al.   STRUCTURE