Network Analysis of a Pkd1-Mouse Model of Autosomal Dominant Polycystic Kidney Disease Identifies HNF4α as a Disease Modifier

Systems biology approach to identify transcriptome reprogramming and candidate microRNA targets during the progression of polycystic kidney disease

(2011) Priyanka Pandey et al.   BMC Systems Biology

Development of a non-targeted metabolomics method to investigate urine in a rat model of polycystic kidney disease

(2011) HAYLEY ABBISS et al.   NEPHROLOGY

Activating AMP-activated protein kinase (AMPK) slows renal cystogenesis

(2011) V. Takiar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

cAMP-mediated regulation of HNF-4α depends on the level of coactivator PGC-1α

(2010) Simon Nitter Dankel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The HALT Polycystic Kidney Disease Trials: Design and Implementation

(2010) A. B. Chapman et al.   Clinical Journal of the American Society of Nephrology

Targeted Deletion of Dicer from Proximal Tubules Protects against Renal Ischemia-Reperfusion Injury

(2010) Q. Wei et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Hepatocyte Nuclear Factor 4 Alpha is Associated with Mesenchymal-Epithelial Transition in Developing Kidneys of C57BL/6 Mice

(2010) Tomonori KANAZAWA et al.   JOURNAL OF VETERINARY MEDICAL SCIENCE

Network medicine: a network-based approach to human disease

(2010) Albert-László Barabási et al.   NATURE REVIEWS GENETICS

Systems biology of autosomal dominant polycystic kidney disease (ADPKD): computational identification of gene expression pathways and integrated regulatory networks

(2009) Xuewen Song et al.   HUMAN MOLECULAR GENETICS

Genetic analyses reveal a requirement for Dicer1 in the mouse urogenital tract

(2009) Laura M. Pastorelli et al.   MAMMALIAN GENOME

A mitotic transcriptional switch in polycystic kidney disease

(2009) Francisco Verdeguer et al.   NATURE MEDICINE

lumi: a pipeline for processing Illumina microarray

(2008) P. Du et al.   BIOINFORMATICS

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

Microarray-based approach identifies microRNAs and their target functional patterns in polycystic kidney disease

(2008) Priyanka Pandey et al.   BMC GENOMICS

Cancer Cell Metabolism: Warburg and Beyond

(2008) Peggy P. Hsu et al.   CELL

Regulation of Hepatocyte Nuclear Factor 4α-mediated Transcription

(2008) Frank J. Gonzalez   Drug Metabolism and Pharmacokinetics

Hepatocyte nuclear factor 4α in the intestinal epithelial cells protects against inflammatory bowel disease

(2008) Sung-Hoon Ahn et al.   INFLAMMATORY BOWEL DISEASES

MicroRNA15a modulates expression of the cell-cycle regulator Cdc25A and affects hepatic cystogenesis in a rat model of polycystic kidney disease

(2008) Seung-Ok Lee et al.   JOURNAL OF CLINICAL INVESTIGATION

Morphogenetic competence of HNF4α-deficient mouse hepatic cells

(2008) Graham P. Hayhurst et al.   JOURNAL OF HEPATOLOGY

A tumor necrosis factor-α–mediated pathway promoting autosomal dominant polycystic kidney disease

(2008) Xiaogang Li et al.   NATURE MEDICINE

Model-based variance-stabilizing transformation for Illumina microarray data

(2008) Simon M. Lin et al.   NUCLEIC ACIDS RESEARCH