Germline Genetic Variants Disturbing the Let-7/LIN28 Double-Negative Feedback Loop Alter Breast Cancer Susceptibility
Published 2011 View Full Article
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Title
Germline Genetic Variants Disturbing the Let-7/LIN28 Double-Negative Feedback Loop Alter Breast Cancer Susceptibility
Authors
Keywords
Breast cancer, MicroRNAs, Untranslated regions, Luciferase assay, Breast tissue, Molecular genetics, Luciferase, Sequence databases
Journal
PLoS Genetics
Volume 7, Issue 9, Pages e1002259
Publisher
Public Library of Science (PLoS)
Online
2011-09-02
DOI
10.1371/journal.pgen.1002259
References
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Related references
Note: Only part of the references are listed.- Let-7 family miRNAs regulate estrogen receptor alpha signaling in estrogen receptor positive breast cancer
- (2010) Yingchun Zhao et al. BREAST CANCER RESEARCH AND TREATMENT
- Single-Nucleotide Polymorphisms Inside MicroRNA Target Sites Influence Tumor Susceptibility
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- Genetic Variants in MicroRNA Biosynthesis Pathways and Binding Sites Modify Ovarian Cancer Risk, Survival, and Treatment Response
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- Double-Negative Feedback Loop between Reprogramming Factor LIN28 and microRNA let-7 Regulates Aldehyde Dehydrogenase 1-Positive Cancer Stem Cells
- (2010) X. Yang et al. CANCER RESEARCH
- Lin28: A MicroRNA Regulator with a Macro Role
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- A Risk Variant in an miR-125b Binding Site in BMPR1B Is Associated with Breast Cancer Pathogenesis
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- An Epigenetic Switch Involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 Links Inflammation to Cell Transformation
- (2009) Dimitrios Iliopoulos et al. CELL
- Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7
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- A functional polymorphism in the promoter region of GSTM1 implies a complex role for GSTM1 in breast cancer
- (2009) Ke-Da Yu et al. FASEB JOURNAL
- Functional polymorphisms, altered gene expression and genetic association link NRH:quinone oxidoreductase 2 to breast cancer with wild-type p53
- (2009) K.-D. Yu et al. HUMAN MOLECULAR GENETICS
- Lin28 promotes transformation and is associated with advanced human malignancies
- (2009) Srinivas R Viswanathan et al. NATURE GENETICS
- Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells
- (2009) John P Hagan et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- MicroRNA polymorphisms: the future of pharmacogenomics, molecular epidemiology and individualized medicine
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- Clinicopathological features of the triple-negative tumors in Chinese breast cancer patients
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- A SNP in a let-7 microRNA Complementary Site in the KRAS 3' Untranslated Region Increases Non-Small Cell Lung Cancer Risk
- (2008) L. J. Chin et al. CANCER RESEARCH
- Lin28 Mediates the Terminal Uridylation of let-7 Precursor MicroRNA
- (2008) Inha Heo et al. MOLECULAR CELL
- A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment
- (2008) Agnieszka Rybak et al. NATURE CELL BIOLOGY
- Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing
- (2008) M. A. Newman et al. RNA
- Selective Blockade of MicroRNA Processing by Lin28
- (2008) S. R. Viswanathan et al. SCIENCE
- let-7 microRNAs in development, stem cells and cancer
- (2008) Ingo Büssing et al. TRENDS IN MOLECULAR MEDICINE
- The emerging landscape of breast cancer susceptibility
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