Phylogenetic Quantification of Intra-tumour Heterogeneity

LRP1B Deletion in High-Grade Serous Ovarian Cancers Is Associated with Acquired Chemotherapy Resistance to Liposomal Doxorubicin

(2012) Prue A. Cowin et al.   CANCER RESEARCH

The Life History of 21 Breast Cancers

(2012) Serena Nik-Zainal et al.   CELL

Clonal selection drives genetic divergence of metastatic medulloblastoma

(2012) Xiaochong Wu et al.   NATURE

Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing

(2012) Li Ding et al.   NATURE

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

(2012) Marco Gerlinger et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sequential genetic change at the TP53 and chemokine receptor CXCR4 locus during transformation of human ovarian surface epithelium

(2012) K M Archibald et al.   ONCOGENE

Accurate Reconstruction of Insertion-Deletion Histories by Statistical Phylogenetics

(2012) Oscar Westesson et al.   PLoS One

Advanced Ovarian Cancer: Multiparametric MR Imaging Demonstrates Response- and Metastasis-specific Effects

(2012) Evis Sala et al.   RADIOLOGY

PhyloSim - Monte Carlo simulation of sequence evolution in the R statistical computing environment

(2011) Botond Sipos et al.   BMC BIOINFORMATICS

Primary Colorectal Cancers and Their Subsequent Hepatic Metastases Are Genetically Different: Implications for Selection of Patients for Targeted Treatment

(2011) J. S. Vermaat et al.   CLINICAL CANCER RESEARCH

Estimation of rearrangement phylogeny for cancer genomes

(2011) C. D. Greenman et al.   GENOME RESEARCH

The role of tandem duplicator phenotype in tumour evolution in high-grade serous ovarian cancer

(2011) Charlotte KY Ng et al.   JOURNAL OF PATHOLOGY

Evolution of platinum resistance in high-grade serous ovarian cancer

(2011) Susanna L Cooke et al.   LANCET ONCOLOGY

Tumour evolution inferred by single-cell sequencing

(2011) Nicholas Navin et al.   NATURE

Integrated genomic analyses of ovarian carcinoma

(2011) D. Bell et al.   NATURE

Evolutionary Distances in the Twilight Zone—A Rational Kernel Approach

(2011) Roland F. Schwarz et al.   PLoS One

Intra-tumour genetic heterogeneity and poor chemoradiotherapy response in cervical cancer

(2010) S L Cooke et al.   BRITISH JOURNAL OF CANCER

Cellular and genetic diversity in the progression of in situ human breast carcinomas to an invasive phenotype

(2010) So Yeon Park et al.   JOURNAL OF CLINICAL INVESTIGATION

The patterns and dynamics of genomic instability in metastatic pancreatic cancer

(2010) Peter J. Campbell et al.   NATURE

Genome remodelling in a basal-like breast cancer metastasis and xenograft

(2010) Li Ding et al.   NATURE

Genomic analysis of genetic heterogeneity and evolution in high-grade serous ovarian carcinoma

(2010) S L Cooke et al.   ONCOGENE

Analysis of the copy number profiles of several tumor samples from the same patient reveals the successive steps in tumorigenesis

(2010) Eric Letouzé et al.   GENOME BIOLOGY

PICNIC: an algorithm to predict absolute allelic copy number variation with microarray cancer data

(2009) C. D. Greenman et al.   BIOSTATISTICS

Inferring tumor progression from genomic heterogeneity

(2009) N. Navin et al.   GENOME RESEARCH

Sensitive and accurate detection of copy number variants using read depth of coverage

(2009) S. Yoon et al.   GENOME RESEARCH

Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

(2009) Sohrab P. Shah et al.   NATURE

Is Tumor Growth Sustained by Rare Cancer Stem Cells or Dominant Clones?

(2008) J. M. Adams et al.   CANCER RESEARCH

The clonal evolution of metastases from primary serous epithelial ovarian cancers

(2008) Lalarukh Khalique et al.   INTERNATIONAL JOURNAL OF CANCER