Limited Agreement of Independent RNAi Screens for Virus-Required Host Genes Owes More to False-Negative than False-Positive Factors

cSSMD: assessing collective activity for addressing off-target effects in genome-scale RNA interference screens

(2011) Xiaohua Douglas Zhang et al.   BIOINFORMATICS

Tissue-specific subnetworks and characteristics of publicly available human protein interaction databases

(2011) Tiago J. S. Lopes et al.   BIOINFORMATICS

Normalizing for individual cell population context in the analysis of high-content cellular screens

(2011) Bettina Knapp et al.   BMC BIOINFORMATICS

Insights into the molecular correlates modulating functional compensation between monogenic and polygenic disease gene duplicates in human

(2011) Soumita Podder et al.   GENOMICS

Uncovering the global host cell requirements for influenza virus replication via RNAi screening

(2011) Silke Stertz et al.   MICROBES AND INFECTION

RNAi screening reveals requirement for host cell secretory pathway in infection by diverse families of negative-strand RNA viruses

(2011) D. Panda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Statistical Inference: The Big Picture

(2011) Robert E. Kass   STATISTICAL SCIENCE

Network-Based Prediction and Analysis of HIV Dependency Factors

(2011) T. M. Murali et al.   PLoS Computational Biology

Vigilance and Validation: Keys to Success in RNAi Screening

(2010) Frederic D. Sigoillot et al.   ACS Chemical Biology

Genomic Screening with RNAi: Results and Challenges

(2010) Stephanie Mohr et al.   Annual Review of Biochemistry

Cellular Networks Involved in the Influenza Virus Life Cycle

(2010) Tokiko Watanabe et al.   Cell Host & Microbe

Gene pathways and subnetworks distinguish between major glioma subtypes and elucidate potential underlying biology

(2010) Stefan Wuchty et al.   JOURNAL OF BIOMEDICAL INFORMATICS

Identifying HIV-1 host cell factors by genome-scale RNAi screening

(2010) Lars Pache et al.   METHODS

Target mRNA abundance dilutes microRNA and siRNA activity

(2010) Aaron Arvey et al.   Molecular Systems Biology

Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication

(2010) Alexander Karlas et al.   NATURE

GOing Bayesian: model-based gene set analysis of genome-scale data

(2010) Sebastian Bauer et al.   NUCLEIC ACIDS RESEARCH

Patterns of HIV-1 Protein Interaction Identify Perturbed Host-Cellular Subsystems

(2010) Jamie I. MacPherson et al.   PLoS Computational Biology

The IFITM Proteins Mediate Cellular Resistance to Influenza A H1N1 Virus, West Nile Virus, and Dengue Virus

(2009) Abraham L. Brass et al.   CELL

Discovery of insect and human dengue virus host factors

(2009) October M. Sessions et al.   NATURE

Population context determines cell-to-cell variability in endocytosis and virus infection

(2009) Berend Snijder et al.   NATURE

Human host factors required for influenza virus replication

(2009) Renate König et al.   NATURE

Statistical methods for analysis of high-throughput RNA interference screens

(2009) Amanda Birmingham et al.   NATURE METHODS

Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application

(2009) Aimee L. Jackson et al.   NATURE REVIEWS DRUG DISCOVERY

A Direct Phenotypic Comparison of siRNA Pools and Multiple Individual Duplexes in a Functional Assay

(2009) Brendon D. Parsons et al.   PLoS One

Host Cell Factors in HIV Replication: Meta-Analysis of Genome-Wide Studies

(2009) Frederic D. Bushman et al.   PLoS Pathogens

Global Analysis of Host-Pathogen Interactions that Regulate Early-Stage HIV-1 Replication

(2008) Renate König et al.   CELL

Genome-Scale RNAi Screen for Host Factors Required for HIV Replication

(2008) Honglin Zhou et al.   Cell Host & Microbe

Drosophila RNAi screen identifies host genes important for influenza virus replication

(2008) Linhui Hao et al.   NATURE

RNA interference screen for human genes associated with West Nile virus infection

(2008) Manoj N. Krishnan et al.   NATURE

Role of Duplicate Genes in Robustness against Deleterious Human Mutations

(2008) Tzu-Lin Hsiao et al.   PLoS Genetics