Flux Imbalance Analysis and the Sensitivity of Cellular Growth to Changes in Metabolite Pools

The dynamics of hybrid metabolic-genetic oscillators

(2013) Ed Reznik et al.   CHAOS

Changes in substrate availability in Escherichia coli lead to rapid metabolite, flux and growth rate responses

(2013) Hilal Taymaz-Nikerel et al.   METABOLIC ENGINEERING

Functioning of a metabolic flux sensor in Escherichia coli

(2013) K. Kochanowski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Ability of Flux Balance Analysis to Predict Evolution of Central Metabolism Scales with the Initial Distance to the Optimum

(2013) William R. Harcombe et al.   PLoS Computational Biology

A Whole-Cell Computational Model Predicts Phenotype from Genotype

(2012) Jonathan R. Karr et al.   CELL

Ultrasensitive regulation of anapleurosis via allosteric activation of PEP carboxylase

(2012) Yi-Fan Xu et al.   Nature Chemical Biology

Multidimensional Optimality of Microbial Metabolism

(2012) R. Schuetz et al.   SCIENCE

Global Network Reorganization During Dynamic Adaptations of Bacillus subtilis Metabolism

(2012) J. M. Buescher et al.   SCIENCE

Temporal Expression-based Analysis of Metabolism

(2012) Sara B. Collins et al.   PLoS Computational Biology

Impact of Stoichiometry Representation on Simulation of Genotype-Phenotype Relationships in Metabolic Networks

(2012) Ana Rita Brochado et al.   PLoS Computational Biology

Regulation and control of metabolic fluxes in microbes

(2011) Luca Gerosa et al.   CURRENT OPINION IN BIOTECHNOLOGY

Bacterial growth laws and their applications

(2011) Matthew Scott et al.   CURRENT OPINION IN BIOTECHNOLOGY

The importance of post-translational modifications in regulating Saccharomyces cerevisiae metabolism

(2011) Ana Paula Oliveira et al.   FEMS YEAST RESEARCH

Escherichia coli responds with a rapid and large change in growth rate upon a shift from glucose-limited to glucose-excess conditions

(2011) Hilal Taymaz-Nikerel et al.   METABOLIC ENGINEERING

Omic data from evolved E. coli are consistent with computed optimal growth from genome-scale models

(2010) Nathan E Lewis et al.   Molecular Systems Biology

What is flux balance analysis?

(2010) Jeffrey D Orth et al.   NATURE BIOTECHNOLOGY

Structural Sources of Robustness in Biochemical Reaction Networks

(2010) G. Shinar et al.   SCIENCE

Connecting extracellular metabolomic measurements to intracellular flux states in yeast

(2009) Monica L Mo et al.   BMC Systems Biology

Flux balance analysis of biological systems: applications and challenges

(2009) K. Raman et al.   BRIEFINGS IN BIOINFORMATICS

Growth-limiting Intracellular Metabolites in Yeast Growing under Diverse Nutrient Limitations

(2009) Viktor M. Boer et al.   MOLECULAR BIOLOGY OF THE CELL

Metabolomics-driven quantitative analysis of ammonia assimilation in E. coli

(2009) Jie Yuan et al.   Molecular Systems Biology

The application of flux balance analysis in systems biology

(2009) Erwin P. Gianchandani et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Integrating metabolic, transcriptional regulatory and signal transduction models in Escherichia coli

(2008) Markus W. Covert et al.   BIOINFORMATICS

Formulating genome-scale kinetic models in the post-genome era

(2008) Neema Jamshidi et al.   Molecular Systems Biology

Metabolic gene regulation in a dynamically changing environment

(2008) Matthew R. Bennett et al.   NATURE

Context-Specific Metabolic Networks Are Consistent with Experiments

(2008) Scott A. Becker et al.   PLoS Computational Biology