PUMA: A Unified Framework for Penalized Multiple Regression Analysis of GWAS Data

Penalized methods for bi-level variable selection

(2013) Patrick Breheny et al.   Statistics and Its Interface

Combined Analysis of Genome-wide Association Studies for Crohn Disease and Psoriasis Identifies Seven Shared Susceptibility Loci

(2012) David Ellinghaus et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Five Years of GWAS Discovery

(2012) Peter M. Visscher et al.   AMERICAN JOURNAL OF HUMAN GENETICS

BAYESIAN HYPER-LASSOS WITH NON-CONVEX PENALIZATION

(2012) Jim E. Griffin et al.   AUSTRALIAN & NEW ZEALAND JOURNAL OF STATISTICS

A novel variational Bayes multiple locus Z-statistic for genome-wide association studies with Bayesian model averaging

(2012) Benjamin A. Logsdon et al.   BIOINFORMATICS

Mouse obesity network reconstruction with a variational Bayes algorithm to employ aggressive false positive control

(2012) Benjamin A Logsdon et al.   BMC BIOINFORMATICS

An efficient multi-locus mixed-model approach for genome-wide association studies in structured populations

(2012) Vincent Segura et al.   NATURE GENETICS

Zinc in Specialized Secretory Tissues: Roles in the Pancreas, Prostate, and Mammary Gland

(2012) Shannon L. Kelleher et al.   Advances in Nutrition

Bayesian variable selection regression for genome-wide association studies and other large-scale problems

(2011) Yongtao Guan et al.   Annals of Applied Statistics

Using Penalised Logistic Regression to Fine Map HLA Variants for Rheumatoid Arthritis

(2011) Charlotte M. Vignal et al.   ANNALS OF HUMAN GENETICS

Stability selection for genome-wide association

(2011) David H. Alexander et al.   GENETIC EPIDEMIOLOGY

Pathway-driven gene stability selection of two rheumatoid arthritis GWAS identifies and validates new susceptibility genes in receptor mediated signalling pathways

(2011) Hariklia Eleftherohorinou et al.   HUMAN MOLECULAR GENETICS

Strong rules for discarding predictors in lasso-type problems

(2011) Robert Tibshirani et al.   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

(2011) Georg B. Ehret et al.   NATURE

Genome partitioning of genetic variation for complex traits using common SNPs

(2011) Jian Yang et al.   NATURE GENETICS

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

(2011) Carl A Anderson et al.   NATURE GENETICS

FaST linear mixed models for genome-wide association studies

(2011) Christoph Lippert et al.   NATURE METHODS

KEGG for integration and interpretation of large-scale molecular data sets

(2011) M. Kanehisa et al.   NUCLEIC ACIDS RESEARCH

The Pfam protein families database

(2011) M. Punta et al.   NUCLEIC ACIDS RESEARCH

Prioritizing GWAS Results: A Review of Statistical Methods and Recommendations for Their Application

(2010) Rita M. Cantor et al.   AMERICAN JOURNAL OF HUMAN GENETICS

GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Sure independence screening in generalized linear models with NP-dimensionality

(2010) Jianqing Fan et al.   ANNALS OF STATISTICS

Nearly unbiased variable selection under minimax concave penalty

(2010) Cun-Hui Zhang   ANNALS OF STATISTICS

Genome-Wide Association Studies: Results from the First Few Years and Potential Implications for Clinical Medicine

(2010) Joel N. Hirschhorn et al.   Annual Review of Medicine

The Bayesian lasso for genome-wide association studies

(2010) Jiahan Li et al.   BIOINFORMATICS

Bioinformatics challenges for genome-wide association studies

(2010) J. H. Moore et al.   BIOINFORMATICS

Association screening of common and rare genetic variants by penalized regression

(2010) H. Zhou et al.   BIOINFORMATICS

A variable selection method for genome-wide association studies

(2010) Qianchuan He et al.   BIOINFORMATICS

Identifying main effects and epistatic interactions from large-scale SNP data via adaptive group Lasso

(2010) Can Yang et al.   BMC BIOINFORMATICS

A variational Bayes algorithm for fast and accurate multiple locus genome-wide association analysis

(2010) Benjamin A Logsdon et al.   BMC BIOINFORMATICS

STAT3 locus in inflammatory bowel disease and multiple sclerosis susceptibility

(2010) M C Cénit et al.   GENES AND IMMUNITY

SNP Selection in genome-wide and candidate gene studies via penalized logistic regression

(2010) Kristin L. Ayers et al.   GENETIC EPIDEMIOLOGY

Progress and Promise of Genome-Wide Association Studies for Human Complex Trait Genetics

(2010) B. E. Stranger et al.   GENETICS

Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease

(2010) Dermot P.B. McGovern et al.   HUMAN MOLECULAR GENETICS

p-Values for High-Dimensional Regression

(2010) Nicolai Meinshausen et al.   JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION

Regularization Parameter Selections via Generalized Information Criterion

(2010) Yiyun Zhang et al.   JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION

The group lasso for logistic regression

(2010) Lukas Meier et al.   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

Stability selection

(2010) Nicolai Meinshausen et al.   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

Hundreds of variants clustered in genomic loci and biological pathways affect human height

(2010) Hana Lango Allen et al.   NATURE

Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes

(2010) Kaixin Zhou et al.   NATURE GENETICS

Multiple common variants for celiac disease influencing immune gene expression

(2010) Patrick C A Dubois et al.   NATURE GENETICS

Estimation of effect size distribution from genome-wide association studies and implications for future discoveries

(2010) Ju-Hyun Park et al.   NATURE GENETICS

Genome-wide meta-analyses identify multiple loci associated with smoking behavior

(2010)   NATURE GENETICS

Common SNPs explain a large proportion of the heritability for human height

(2010) Jian Yang et al.   NATURE GENETICS

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

(2010) Eli A Stahl et al.   NATURE GENETICS

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

(2010) Benjamin F Voight et al.   NATURE GENETICS

Analysing biological pathways in genome-wide association studies

(2010) Kai Wang et al.   NATURE REVIEWS GENETICS

Mammalian Zinc Transporters: Nutritional and Physiologic Regulation

(2009) Louis A. Lichten et al.   Annual Review of Nutrition

A Genomewide Association Study Points to Multiple Loci That Predict Antidepressant Drug Treatment Outcome in Depression

(2009) Marcus Ising et al.   ARCHIVES OF GENERAL PSYCHIATRY

Genome-wide association analysis by lasso penalized logistic regression

(2009) Tong Tong Wu et al.   BIOINFORMATICS

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

(2009) Jeffrey C Barrett et al.   NATURE GENETICS

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

(2009) L. A. Hindorff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extra-adrenal glucocorticoid synthesis in the intestinal epithelium: more than a drop in the ocean?

(2009) Mario Noti et al.   Seminars in Immunopathology

Capturing the Spectrum of Interaction Effects in Genetic Association Studies by Simulated Evaporative Cooling Network Analysis

(2009) Brett A. McKinney et al.   PLoS Genetics

Designing Genome-Wide Association Studies: Sample Size, Power, Imputation, and the Choice of Genotyping Chip

(2009) Chris C. A. Spencer et al.   PLoS Genetics

Evaluating the Effects of Imputation on the Power, Coverage, and Cost Efficiency of Genome-wide SNP Platforms

(2008) Carl A. Anderson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genome-wide association study of rheumatoid arthritis in the Spanish population:KLF12as a risk locus for rheumatoid arthritis susceptibility

(2008) Antonio Julià et al.   ARTHRITIS AND RHEUMATISM

Extended Bayesian information criteria for model selection with large model spaces

(2008) J. Chen et al.   BIOMETRIKA

Variable selection for large p small n regression models with incomplete data: Mapping QTL with epistases

(2008) Min Zhang et al.   BMC BIOINFORMATICS

Sure independence screening for ultrahigh dimensional feature space

(2008) Jianqing Fan et al.   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

Personal genomes: The case of the missing heritability

(2008) Brendan Maher   NATURE

Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci

(2008) Jason D Cooper et al.   NATURE GENETICS

A navigator for human genome epidemiology

(2008) Wei Yu et al.   NATURE GENETICS

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

(2008) Jeffrey C Barrett et al.   NATURE GENETICS

Simultaneous Analysis of All SNPs in Genome-Wide and Re-Sequencing Association Studies

(2008) Clive J. Hoggart et al.   PLoS Genetics