An Evolutionary Trade-Off between Protein Turnover Rate and Protein Aggregation Favors a Higher Aggregation Propensity in Fast Degrading Proteins

Functional interactions as a survival strategy against abnormal aggregation

(2010) Masino Laura et al.   FASEB JOURNAL

Proteome-Level Interplay between Folding and Aggregation Propensities of Proteins

(2010) Gian Gaetano Tartaglia et al.   JOURNAL OF MOLECULAR BIOLOGY

Exploring the sequence determinants of amyloid structure using position-specific scoring matrices

(2010) Sebastian Maurer-Stroh et al.   NATURE METHODS

Babelomics: an integrative platform for the analysis of transcriptomics, proteomics and genomic data with advanced functional profiling

(2010) Ignacio Medina et al.   NUCLEIC ACIDS RESEARCH

Protein Aggregation Profile of the Bacterial Cytosol

(2010) Natalia S. de Groot et al.   PLoS One

Identifying the amylome, proteins capable of forming amyloid-like fibrils

(2010) Lukasz Goldschmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biological and Chemical Approaches to Diseases of Proteostasis Deficiency

(2009) Evan T. Powers et al.   Annual Review of Biochemistry

Protein sequences encode safeguards against aggregation

(2009) Joke Reumers et al.   HUMAN MUTATION

The IntAct molecular interaction database in 2010

(2009) B. Aranda et al.   NUCLEIC ACIDS RESEARCH

Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging

(2009) A. Ben-Zvi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Physicochemical principles that regulate the competition between functional and dysfunctional association of proteins

(2009) S. Pechmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Short protein segments can drive a non-fibrillizing protein into the amyloid state

(2009) P. K. Teng et al.   PROTEIN ENGINEERING DESIGN & SELECTION

BETASCAN: Probable β-amyloids Identified by Pairwise Probabilistic Analysis

(2009) Allen W. Bryan et al.   PLoS Computational Biology

GEOmetadb: powerful alternative search engine for the Gene Expression Omnibus

(2008) Y. Zhu et al.   BIOINFORMATICS

The Zyggregator method for predicting protein aggregation propensities

(2008) Gian Gaetano Tartaglia et al.   CHEMICAL SOCIETY REVIEWS

Protein misfolding and disease: from the test tube to the organism

(2008) Leila M Luheshi et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Alterations of activity and intracellular distribution of the 20S proteasome in ageing retinal pigment epithelial cells

(2008) Yue Li et al.   EXPERIMENTAL GERONTOLOGY

Genetic Evidence Linking Age-Dependent Attenuation of the 26S Proteasome with the Aging Process

(2008) A. Tonoki et al.   MOLECULAR AND CELLULAR BIOLOGY

Misfolded proteins partition between two distinct quality control compartments

(2008) Daniel Kaganovich et al.   NATURE

Babelomics: advanced functional profiling of transcriptomics, proteomics and genomics experiments

(2008) F. Al-Shahrour et al.   NUCLEIC ACIDS RESEARCH

Global Protein Stability Profiling in Mammalian Cells

(2008) H.-C. S. Yen et al.   SCIENCE

Adapting Proteostasis for Disease Intervention

(2008) William E. Balch et al.   SCIENCE

Integrating the stress response: lessons for neurodegenerative diseases from C. elegans

(2008) Veena Prahlad et al.   TRENDS IN CELL BIOLOGY

Aggregation Propensity of the Human Proteome

(2008) Elodie Monsellier et al.   PLoS Computational Biology