Review
Chemistry, Multidisciplinary
V Haridas
Summary: The spontaneous self-assembly of amphiphiles is a unique feature in biological evolution, attracting scientists from various disciplines to study nature's organizational power. Recent advances have been made in designing and understanding the mechanism of spherical vesicular assembly. Nonlipidated molecular architecture for vesicle design represents a paradigm shift in vesicular research, with potential applications in drug delivery, biomolecule transport, and materials science. Pseudopeptide-based molecules have challenged traditional notions of vesicle formation, offering new insights into protocell models, membrane fusion, and vesiculation mechanisms.
ACCOUNTS OF CHEMICAL RESEARCH
(2021)
Review
Microbiology
Evgeniya V. Prazdnova, Andrey V. Gorovtsov, Nikita G. Vasilchenko, Maxim P. Kulikov, Varvara N. Statsenko, Anna A. Bogdanova, Alexandr G. Refeld, Yaroslav A. Brislavskiy, Vladimir A. Chistyakov, Michael L. Chikindas
Summary: This review focuses on the mechanisms of quorum-sensing suppression by Gram-positive microorganisms and its practical applications in food fermentation, probiotics, and biotechnology. It also discusses the possible evolutionary role of quorum-quenching mechanisms during the development of interspecies interactions of bacteria.
Article
Biotechnology & Applied Microbiology
Jose Miguel D. Robes, Marvin A. Altamia, Ethan G. Murdock, Gisela P. Concepcion, Margo G. Haygood, Aaron W. Puri
Summary: Bacteria play essential roles as symbionts in animals, but little is known about the molecular details of these relationships. The formation and maintenance of the relationship between shipworms and their bacterial symbionts remain unknown. This study identified a quorum sensing system in a shipworm symbiont and revealed its importance in regulating secondary metabolism. Understanding the molecular details of symbiotic relationships is crucial and may aid in drug discovery using these organisms.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2022)
Review
Polymer Science
Moupriya Nag, Dibyajit Lahiri, Dipro Mukherjee, Ritwik Banerjee, Sayantani Garai, Tanmay Sarkar, Sujay Ghosh, Ankita Dey, Sougata Ghosh, Smaranika Pattnaik, Hisham Atan Edinur, Zulhisyam Abdul Kari, Siddhartha Pati, Rina Rani Ray
Summary: Chitosan and its nano materials show potential in combating drug resistance by disrupting quorum sensing in microbial biofilms, offering a solution for treating chronic infections and preparing medical devices. Through interaction with amino groups on microorganisms, they disrupt membrane permeability and induce cell death.
Article
Medicine, Research & Experimental
Balamurugan Palaniappan, Adline Princy Solomon, David C. Raj
Summary: This study focused on targeting the quorum sensing regulator AgrA of Staphylococcus aureus to reduce bacterial virulence through drug repurposing. The results showed that bumetanide effectively inhibited AgrA and reduced the expression of virulence genes in S. aureus. In vivo studies demonstrated the efficacy of bumetanide in controlling ulcer development and promoting wound healing in mice.
Review
Chemistry, Multidisciplinary
Juan Wang, Pepijn W. H. Pinkse, Loes Segerink, Jan C. T. Eijkel
Summary: Photonic crystals are materials that can confine and manipulate incident light, and have been extensively studied for the development of optical sensors with high adsorption and enhanced light-matter interaction. They are mainly utilized through five sensing principles, including sensing of refractive index variations, sensing by lattice spacing variations, enhanced fluorescence spectroscopy, surface-enhanced Raman spectroscopy, and configuration transitions.
Article
Environmental Sciences
Yue Li, Lexin Xia, Jian Chen, Yulu Lian, Ajai A. Dandekar, Feng Xu, Meizhen Wang
Summary: The study reveals a significant increase in the minimum inhibitory concentration of evolved Pseudomonas aeruginosa PAO1 under sub-lethal conditions, associated with mutations in mpl and ampD, and overexpression of quorum sensing genes. The involvement of quorum sensing in antibiotic resistance evolution is highlighted, showing a multifactorial contribution to observed phenotypes.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Biochemistry & Molecular Biology
Dagmawi Abebe Zewude, Takako Noguchi, Kimihiko Sato, Hironori Izawa, Shinsuke Ifuku
Summary: In this study, chitin nanoparticles were successfully prepared by alkaline treatment and regeneration, which showed small particle size, high dispersibility, and high heat resistance. Compared to nanofibers, nanoparticles had lower viscosity, allowing for preparation at higher concentrations, and can be easily redispersed in water after concentration.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Materials Science, Multidisciplinary
Pierfrancesco Gaziano, Elisabetta Monaldo, Cristina Falcinelli, Giuseppe Vairo
Summary: In this paper, a multiscale modelling strategy is used to analyze the elasto-damage response of osteons, providing a refined mechanical description of cortical bone tissue. The structural features of osteons and the equivalent mechanical response of their constituents are described. Finite-element techniques are used to simulate the experimental tests of isolated osteons under different loading conditions.
JOURNAL OF THE MECHANICS AND PHYSICS OF SOLIDS
(2022)
Article
Agricultural Engineering
Hui-min Fu, Jinfeng Wang, Hongqiang Ren, Lili Ding
Summary: Adding specialized Quorum Sensing bacteria (sphingomonas rubra BH3(T)) can accelerate biofilm formation and operational performance of moving bed biofilm reactor (MBBR) at 5 ? by increasing biofilm thickness, biofilm activity, and nitrifying bacteria abundance. The study also found that BH3(T) contributed to higher species richness and triggered the rapid growth of precursor and multifunctional microorganisms at low temperatures.
BIORESOURCE TECHNOLOGY
(2022)
Article
Ecology
Sven P. Tobias-Hunefeldt, Jess Wenley, Federico Baltar, Sergio E. Morales
Summary: The study revealed that bottom-up selection plays a crucial role in the early stages of microbial community assembly, while top-down predation becomes increasingly important over time. Wooden substrates promote heterotrophic growth, whereas inert substrates select for autotrophs, as they lack degradable material. Late communities are primarily under top-down control, with large predators pruning heterotrophs and leading to increased understanding of ecological processes guiding community assembly.
Article
Engineering, Environmental
Qian Wang, Tianqi Zhang, Guangxue Wu, Qiyong Xu
Summary: The co-disposal of bottom ash in landfills accelerates geotextile clogging and decreases landfill stability, potentially due to increased AHLs content. Higher AHLs content can increase bio-clogging, with EPS aggregation stimulated by higher Ca2+ and Mg2+ in the bottom ash co-disposal landfill.
Article
Green & Sustainable Science & Technology
Callum Milne, Shahin Jalili, Alireza Maheri
Summary: This study introduces a new cost model for OWF decommissioning, which estimates the costs of removal and transportation phases using a bottom-up approach, and further estimates the overall decommissioning costs through project percentage breakdown analysis. The research findings demonstrate that the proposed cost model efficiently estimates the removal and transportation costs, and can be adapted to estimate the overall decommissioning costs.
SUSTAINABLE ENERGY TECHNOLOGIES AND ASSESSMENTS
(2021)
Review
Microbiology
Rohit Patel, Mansi Soni, Bilv Soyantar, Suruchi Shivangi, Swati Sutariya, Meenu Saraf, Dweipayan Goswami
Summary: The indiscriminate use of antibiotics has led to the emergence of drug-resistant strains. Many infectious diseases are caused by microbes that can communicate through quorum sensing (QS), and interfering with QS can effectively control their pathogenicity. Inhibition of QS has become a promising approach for developing new drugs, and various quorum sensing inhibitors (QSIs) have been identified. This review provides an overview of the QS mechanism, QS inhibition, and compounds with anti-QS potential, as well as the possibility of quorum sensing resistance.
ARCHIVES OF MICROBIOLOGY
(2023)
Article
Geosciences, Multidisciplinary
F. Di Giuseppe, A. Benedetti, R. Coughlan, C. Vitolo, M. Vuckovic
Summary: This study improves estimates of fire emissions by using above ground biomass as a proxy observation for fuel load, eliminating the need for indirect estimates from remotely sensed data or inflation factors.
GEOPHYSICAL RESEARCH LETTERS
(2021)
Review
Biochemical Research Methods
Sara Hooshangi, William E. Bentley
CURRENT OPINION IN BIOTECHNOLOGY
(2008)
Article
Biotechnology & Applied Microbiology
Chen-Yu Tsao, Sara Hooshangi, Hsuan-Chen Wu, James J. Valdes, William E. Bentley
METABOLIC ENGINEERING
(2010)
Proceedings Paper
Computer Science, Artificial Intelligence
Steven Bradley, Miranda C. Parker, Rukiye Altin, Lecia Barker, Sara Hooshangi, Samia Kamal, Thom Kunkeler, Ruth G. Lennon, Fiona McNeill, Julia Minguillon, Jack Parkinson, Svetlana Peltsverger, Naaz Sibia
Summary: This study aims to understand the interests and factors affecting the choices of female students through data analysis, in order to promote gender inclusivity in the field of computer science.
PROCEEDINGS OF THE 2023 CONFERENCE ON INNOVATION AND TECHNOLOGY IN COMPUTER SCIENCE EDUCATION, ITICSE 2023, VOL. 2
(2023)
Proceedings Paper
Computer Science, Theory & Methods
Sara Hooshangi, Ryan Buxton, Margaret Ellis
Summary: This paper presents the impact of integrating co-curricular activities and practical skills into the undergraduate CS curriculum. Through surveys and data analysis, the study showcases how students utilize practical skills, their perception of co-curricular activities, and the positive impact of course redesign on the overall student experience.
PROCEEDINGS OF THE 27TH ACM CONFERENCE ON INNOVATION AND TECHNOLOGY IN COMPUTER SCIENCE EDUCATION, ITICSE 2022, VOL 1
(2022)
Proceedings Paper
Computer Science, Theory & Methods
Sara Hooshangi, Margaret Ellis, Stephen H. Edwards
Summary: Performance in CS1 and introductory CS courses has been extensively studied, but less research is available on performance in CS2. This study builds upon previous research and considers factors such as CS1 pathways and the number of previous college CS courses. The findings indicate that gender and race are not significant factors, but undeclared engineering majors perform well and students with CS1 transfer credits have lower pass rates.
PROCEEDINGS OF THE 53RD ACM TECHNICAL SYMPOSIUM ON COMPUTER SCIENCE EDUCATION (SIGCSE 2022), VOL 1
(2022)
Proceedings Paper
Computer Science, Theory & Methods
Joshua Adams, Brian Hainey, Laurie White, Derek Foster, Narine Hall, Mark Hills, Sara Hooshangi, Karthik Kuber, Sajid Nazir, Majd Sakr, Lee Stott, Carmen Taglienti
ITICSE-WGR'20: PROCEEDINGS OF THE WORKING GROUP REPORTS ON INNOVATION AND TECHNOLOGY IN COMPUTER SCIENCE EDUCATION
(2020)
Proceedings Paper
Engineering, Electrical & Electronic
Chelsea G. Bender, Jason C. Hoffstot, Brian T. Combs, Sara Hooshangi, Justin Cappos
2017 IEEE SENSORS APPLICATIONS SYMPOSIUM (SAS)
(2017)
Proceedings Paper
Computer Science, Theory & Methods
Sara Hooshangi, Subhasish Dasgupta
AMCIS 2017 PROCEEDINGS
(2017)
Proceedings Paper
Computer Science, Interdisciplinary Applications
Jurgen Borstler, Harald Stoerrle, Daniel Toll, Jelle van Assema, Rodrigo Duran, Sara Hooshangi, Johan Jeuring, Hieke Keuning, Carsten Kleiner, Bonnie MacKellar
ITICSE-WGR'17: PROCEEDINGS OF THE 2017 ITICSE CONFERENCE WORKING GROUP REPORTS
(2017)
Proceedings Paper
Education, Scientific Disciplines
Sara Hooshangi, Jonathan Wallford, Tara Behrend
FRONTIERS IN EDUCATION CONFERENCE (FIE), 2015
(2015)
Article
Mathematics, Applied
S Hooshangi, R Weiss
Article
Multidisciplinary Sciences
S Hooshangi, S Thiberge, R Weiss
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2005)
Article
Biophysics
XJ Feng, S Hooshangi, D Chen, GY Li, R Weiss, H Rabitz
BIOPHYSICAL JOURNAL
(2004)