Molecular Dynamics Simulations of Forced Unbending of Integrin αVβ3

Forcing Switch from Short- to Intermediate- and Long-lived States of the αA Domain Generates LFA-1/ICAM-1 Catch Bonds

(2010) Wei Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Infrastructure for the life sciences: design and implementation of the UniProt website

(2009) Eric Jain et al.   BMC BIOINFORMATICS

Structure of an integrin with an αI domain, complement receptor type 4

(2009) Can Xie et al.   EMBO JOURNAL

Integrin Activation Dynamics between the RGD-binding Site and the Headpiece Hinge

(2009) Eileen Puklin-Faucher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Demonstration of catch bonds between an integrin and its ligand

(2009) Fang Kong et al.   JOURNAL OF CELL BIOLOGY

Crystal structure of the complete integrin αVβ3 ectodomain plus an α/β transmembrane fragment

(2009) Jian-Ping Xiong et al.   JOURNAL OF CELL BIOLOGY

Dynamics of β3 integrin I-like and hybrid domains: Insight from simulations on the mechanism of transition between open and closed forms

(2009) Thomas Gaillard et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Targeted molecular dynamics reveals overall common conformational changes upon hybrid domain swing-out in β3 integrins

(2009) Davide Provasi et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Mechanically Activated Integrin Switch Controls  5 1 Function

(2009) J. C. Friedland et al.   SCIENCE

A Naturally Occurring Extracellular α−β Clasp Contributes to Stabilization of β3 Integrins in a Bent, Resting Conformation†

(2008) Anthony N. Vomund et al.   BIOCHEMISTRY

Key Interactions in Integrin Ectodomain Responsible for Global Conformational Change Detected by Elastic Network Normal-Mode Analysis

(2008) Atsushi Matsumoto et al.   BIOPHYSICAL JOURNAL

Structure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied Forces

(2008) Jianghai Zhu et al.   MOLECULAR CELL

Integrin Conformational Regulation: Uncoupling Extension/Tail Separation from Changes in the Head Region by a Multiresolution Approach

(2008) Mattia Rocco et al.   STRUCTURE