Modeling Reveals Bistability and Low-Pass Filtering in the Network Module Determining Blood Stem Cell Fate

The transcriptional program controlled by the stem cell leukemia gene Scl/Tal1 during early embryonic hematopoietic development

(2009) N. K. Wilson et al.   BLOOD

Expression of the leukemia oncogene Lmo2 is controlled by an array of tissue-specific elements dispersed over 100 kb and bound by Tal1/Lmo2, Ets, and Gata factors

(2009) J.-R. Landry et al.   BLOOD

Incorporating nucleosomes into thermodynamic models of transcription regulation

(2009) T. Raveh-Sadka et al.   GENOME RESEARCH

From genes to cells to tissues—modelling the haematopoietic system

(2009) Samuel D. Foster et al.   Molecular BioSystems

Runx genes are direct targets of Scl/Tal1 in the yolk sac and fetal liver

(2008) J.-R. Landry et al.   BLOOD

Endoglin expression in blood and endothelium is differentially regulated by modular assembly of the Ets/Gata hemangioblast code

(2008) J. E. Pimanda et al.   BLOOD

Hematopoiesis: An Evolving Paradigm for Stem Cell Biology

(2008) Stuart H. Orkin et al.   CELL

Transcriptional regulatory networks in haematopoiesis

(2008) Diego Miranda-Saavedra et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

A novel mode of enhancer evolution: The Tal1 stem cell enhancer recruited a MIR element to specifically boost its activity

(2008) A. M. Smith et al.   GENOME RESEARCH

Transcriptome-wide noise controls lineage choice in mammalian progenitor cells

(2008) Hannah H. Chang et al.   NATURE

Chromatin decouples promoter threshold from dynamic range

(2008) Felix H. Lam et al.   NATURE

Global Protein Stability Profiling in Mammalian Cells

(2008) H.-C. S. Yen et al.   SCIENCE