Article
Biology
Camille Marques Alves, Andressa Rastrelo Rezende, Isabela Alves Marques, Eduardo Lazaro Martins Naves
Summary: Spasticity is a motor disorder affecting millions globally, and its accurate evaluation is crucial for rehabilitation. While current methods lack objective quantification, the newly developed SpES provides a quantitative approach embedded with the TSRT method for assessing hypertonia in clinical practice.
COMPUTERS IN BIOLOGY AND MEDICINE
(2021)
Article
Engineering, Biomedical
Alexa B. Keeling, Mark Piitz, Jennifer A. Semrau, Michael D. Hill, Stephen H. Scott, Sean P. Dukelow
Summary: The study developed robotic upper extremity therapy tasks for subacute stroke patients and found significant improvements in FMA UE, ARAT, FIM, and Visually Guided Reaching scores in the robotic therapy group post-intervention. However, only FIM and Arm Position Match scores improved in the control group over the same time period. The Kinarm therapy tasks show potential for improving outcomes in subacute stroke, but further studies are needed to confirm the benefits in a larger cohort.
JOURNAL OF NEUROENGINEERING AND REHABILITATION
(2021)
Article
Robotics
Nathaniel Dennler, Amelia Cain, Erica De Guzmann, Claudia Chiu, Carolee J. Winstein, Stefanos Nikolaidis, Maja J. Mataric
Summary: An often-observed phenomenon in survivors of hemispheric stroke is the overreliance on the less-affected limb for functional tasks, despite the recovered capacity of the paretic limb. To better quantify this arm nonuse, a bimanual arm reaching test with a robot (BARTR) was developed. The BARTR is a valid, reliable, and simple instrument for assessing arm nonuse in chronic stroke survivors.
Article
Clinical Neurology
Jord J. T. Vink, Eline C. C. van Lieshout, Willem M. M. Otte, Ruben P. A. van Eijk, Mirjam Kouwenhoven, Sebastiaan F. W. Neggers, H. Bart van der Worp, Johanna M. A. Visser-Meily, Rick M. M. Dijkhuizen
Summary: Inhibitory repetitive transcranial magnetic stimulation treatment started within 3 weeks after stroke onset promotes upper limb motor recovery, reduces disability and dependence, and leads to earlier discharge from the rehabilitation center.
Article
Medicine, General & Internal
Hiroyuki Tashima, Mari Ito, Michiyuki Kawakami, Ryota Ishii, Yuta Miyazaki, Tomonori Akimoto, Masahiro Tsujikawa, Keigo Kobayashi, Kunitsugu Kondo, Tetsuya Tsuji
Summary: This study examines factors related to post-stroke pneumonia in subacute stroke patients and finds that signs of pulmonary infection on chest CT at admission is an independent risk factor for pneumonia.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Clinical Neurology
Linda L. D. Zhong, Ya Zheng, Alexander Y. Lau, Norman Wong, Liang Yao, Xingyao Wu, Tengteng Shao, Zhenxing Lu, Huijuan Li, Chun Sum Yuen, Jianwen Guo, Suzanne Lo, Janita Chau, Kam Wa Chan, Bacon Fung Leung Ng, Zhaoxiang Bian, Edwin Chau-Leung Yu
Summary: The meta-analysis showed that the combined use of acupuncture and Western medicine was more effective in improving dependency and swallowing function in stroke rehabilitation compared to using Western medicine alone. Additionally, the combined use of Chinese medicine and Western medicine showed potential superiority in improving depression. However, more rigorous and longer-term randomized controlled trials are needed to confirm these findings.
STROKE AND VASCULAR NEUROLOGY
(2022)
Article
Multidisciplinary Sciences
Rui Wang, Yuqing Song, Yueyue He, Shiyan Long, Ling Feng
Summary: This study aimed to explore the status and related factors of knowledge, attitude, and practice (KAP) of poststroke dysphagia among neurological nurses in China. A survey was conducted among 707 neurological nurses from 40 tertiary hospitals in Southwest China. The study found that the knowledge score of neurological nurses in poststroke dysphagia was relatively low, indicating a need for improvement. However, the attitude and practice scores were much better. Therefore, it is recommended that managers and nursing researchers provide effective training to improve the knowledge, attitude, and practice of neurological nurses towards poststroke dysphagia, and ultimately improve patients' health outcomes.
Review
Clinical Neurology
Olivier Uwishema, Christin Berjaoui, Ines F. Silva Correia, Heeba Anis, Ece Karabulut, Dina Essayli, Melissa Mhanna, Adekunbi Oluyemisi
Summary: Medical care for acute ischemic stroke in Africa is suboptimal, with inadequate resources, public awareness, and delayed treatment. We urge African leaders and private entities to invest in stroke care, improve infrastructure, and enhance international and national collaboration for improved treatment affordability.
EUROPEAN JOURNAL OF NEUROLOGY
(2022)
Article
Rehabilitation
Ilse J. Blokland, Floor P. Groot, Nadine H. G. Logt, Coen A. M. van Bennekom, Jos J. de Koning, Jaap H. van Dieen, Han Houdijk
Summary: This study aimed to provide reference values of cardiorespiratory fitness for individuals post-stroke in clinical rehabilitation and to explore characteristics associated with cardiorespiratory fitness post-stroke. The results showed that age, sex, beta-blocker medication, body mass index, and motor ability were related to lower cardiorespiratory fitness.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2023)
Article
Plant Sciences
Huijuan Li, Wai Ching Lam, Jianwen Guo, Jiangang Zheng, Chun Hoi Cheung, Zhaoxiang Bian, Alexander Y. Lau, Linda L. D. Zhong
Summary: Stroke is the second leading cause of death worldwide, and this is also the case in Hong Kong. Although integrative medicine approaches are widely used, there is a lack of guideline for stroke management and rehabilitation. Therefore, a framework for the development of an integrative medicine clinical practice guideline for stroke has been designed.
Article
Multidisciplinary Sciences
Adriana Cancrini, Paolo Baitelli, Matteo Lavit Nicora, Matteo Malosio, Alessandra Pedrocchi, Alessandro Scano
Summary: This study investigates the effect of robot assistance on task performance and muscle synergies in healthy individuals. The results show that assistance improves task performance but has limited impact on muscle synergies.
Article
Medicine, General & Internal
Monique Messaggi Sartor, Jennifer Grau-Sanchez, Anna Guillen-Sola, Roser Boza, Josep Puig, Cathy Stinear, Andrea Morgado-Perez, Esther Duarte
Summary: This study aims to describe an intensive rehabilitation programme for stroke patients in an inpatient facility, measuring the types and amount of therapies provided and reporting functional outcomes. Using a prospective observational cohort study design, data will be collected from patients with subacute stroke to assess the effectiveness of the rehabilitation interventions.
Article
Psychology, Multidisciplinary
Walaa Khazaal, Maram Taliani, Celina Boutros, Linda Abou-Abbas, Hassan Hosseini, Pascale Salameh, Najwane Said Sadier
Summary: This study investigated the short-term psychological consequences of stroke among Lebanese survivors and identified significant associations between anxiety, depression, and various variables. Results showed that neuropathic pain, fatigue, cognitive impairment, anxiety, and depression were common complications post-stroke among Lebanese survivors. Multivariate logistic regression analysis revealed risk factors such as pain and immobility-related complications for anxiety and depression, highlighting the need for patient-centered interventions to address these issues.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Rehabilitation
Yanan Zheng, Ying Zhang, Hongli Li, Lei Qiao, Weijie Fu, Long Yu, Gaiyan Li, Jianzhong Yang, Weidong Ni, Zhijie Yong, Yanmin Wang, Hang Fan
Summary: This study compared the effects of Liuzijue Qigong and conventional respiratory training on stroke patients and found that Liuzijue exercise showed more changes in improving trunk control ability, respiratory muscle functions, and activities of daily living ability in patients at an early recovery stage from stroke.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2021)
Article
Medicine, General & Internal
Amreen Mahmood, Anagha Deshmukh, Manikandan Natarajan, Dianne Marsden, Glade Vyslysel, Sebastian Padickaparambil, T. S. Shwetha, Artur Direito, Senthil Kumaran, N. Girish, Harpreet Sachdev, Sundar Kumar Veluswamy, Suruliraj Karthikbabu, B. Unnikrishnan, Coralie English, John M. Solomon
Summary: Through a Delphi consensus process involving experts from various fields, a framework of nine strategies to enhance adherence to home-based exercises after stroke was developed. This framework provides practical methods for clinicians to support exercise adherence among stroke survivors in both research and clinical settings.
Review
Neurosciences
Sook-Lei Liew, Artemis Zavaliangos-Petropulu, Neda Jahanshad, Catherine E. Lang, Kathryn S. Hayward, Keith R. Lohse, Julia M. Juliano, Francesca Assogna, Lee A. Baugh, Anup K. Bhattacharya, Bavrina Bigjahan, Michael R. Borich, Lara A. Boyd, Amy Brodtmann, Cathrin M. Buetefisch, Winston D. Byblow, Jessica M. Cassidy, Adriana B. Conforto, R. Cameron Craddock, Michael A. Dimyan, Adrienne N. Dula, Elsa Ermer, Mark R. Etherton, Kelene A. Fercho, Chris M. Gregory, Shahram Hadidchi, Jess A. Holguin, Darryl H. Hwang, Simon Jung, Steven A. Kautz, Mohamed Salah Khlif, Nima Khoshab, Bokkyu Kim, Hosung Kim, Amy Kuceyeski, Martin Lotze, Bradley J. MacIntosh, John L. Margetis, Feroze B. Mohamed, Fabrizio Piras, Ander Ramos-Murguialday, Genevieve Richard, Pamela Roberts, Andrew D. Robertson, Jane M. Rondina, Natalia S. Rost, Nerses Sanossian, Nicolas Schweighofer, Na Jin Seo, Mark S. Shiroishi, Surjo R. Soekadar, Gianfranco Spalletta, Cathy M. Stinear, Anisha Suri, Wai Kwong W. Tang, Gregory T. Thielman, Daniela Vecchio, Arno Villringer, Nick S. Ward, Emilio Werden, Lars T. Westlye, Carolee Winstein, George F. Wittenberg, Kristin A. Wong, Chunshui Yu, Steven C. Cramer, Paul M. Thompson
Summary: The ENIGMA Stroke Recovery working group aims to understand the relationship between brain and behavior using meta- and mega-analytic approaches. They have developed neuroinformatics protocols and methods to manage large-scale data from over 2,100 stroke patients. The challenges and recommendations for data harmonization in stroke research are discussed.
HUMAN BRAIN MAPPING
(2022)
Article
Clinical Neurology
Gowun Kim, ByeongChang Jeong, Myungwon Choi, Won-Seok Kim, Cheol E. Han, Nam-Jong Paik
Summary: Subcortical aphasia is characterized by damage in subcortical brain areas without affecting cortical functions. This study used VLSM and atlas-based analyses to investigate neural substrates associated with subcortical aphasia in stroke patients, identifying specific white matter tracts and subcortical structures that are more affected in the aphasia group. The findings highlight the importance of language processing in the left hemisphere around the sylvian fissure.
JOURNAL OF THE NEUROLOGICAL SCIENCES
(2021)
Article
Clinical Neurology
Won Seok William Hyung, June Kang, Junhyung Kim, Suji Lee, HyunChul Youn, Byung-Joo Ham, Changsu Han, Sangil Suh, Cheol E. Han, Hyun-Ghang Jeong
Summary: The study aimed to identify differences in structural and functional changes between prodromal AD and LLD-related MCI in elderly patients through voxel-based morphometry and FC analysis. Subjects with MDD or amyloid deposition showed greater volume reduction in certain brain areas, and MDD groups had lower FC than STD groups in specific regions. The functional differences associated with amyloid plaques were more evident in the STD group than in the MDD group.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Multidisciplinary Sciences
Suji Lee, Daegyeom Kim, HyunChul Youn, Won Seok William Hyung, Sangil Suh, Marcus Kaiser, Cheol E. Han, Hyun-Ghang Jeong
Summary: The study found that the topological features of brain networks are influenced by amyloid accumulation, which affects cognitive decline in depressed older adults with MCI. Disrupted network connectivity associated with amyloid accumulation is linked to impaired recall and recognition, while altered networks involved in fronto-limbic circuitry dysfunction are more influential in inattention and dysexecutive function.
SCIENTIFIC REPORTS
(2021)
Article
Geriatrics & Gerontology
Kaori L. Ito, Laura Cao, Renee Reinberg, Brenton Keller, John Monterosso, Nicolas Schweighofer, Sook-Lei Liew
Summary: The study compared online and in-person performance on the two-stage Markov task and found no differences in estimated free parameters between different age groups. It also replicated previous findings that young adults are more goal-directed than older adults.
FRONTIERS IN AGING NEUROSCIENCE
(2021)
Article
Clinical Neurology
Bokkyu Kim, Nicolas Schweighofer, Justin P. Haldar, Richard M. Leahy, Carolee J. Winstein
Summary: The study revealed that CST metrics could predict improvements in distal upper extremity motor function in chronic stroke survivors, particularly in the context of an UE rehabilitation trial.
JOURNAL OF NEUROLOGIC PHYSICAL THERAPY
(2021)
Article
Neurosciences
Sujin Kim, Cheol E. Han, Bokkyu Kim, Carolee J. Winstein, Nicolas Schweighofer
Summary: In reaching movements following stroke, right-hemiparetic individuals show a habitual pattern of arm choice, while left-hemiparetic individuals choose their paretic left arm more optimally.
JOURNAL OF NEUROPHYSIOLOGY
(2022)
Article
Multidisciplinary Sciences
Sungmin Cho, Won Kee Chang, Jihong Park, Seung Hyun Lee, Jongseung Lee, Cheol E. Han, Nam-Jong Paik, Won-Seok Kim
Summary: Virtual prism adaptation therapy (VPAT) combines immersive virtual reality with a depth-sensing camera to provide a better way of quantifying and monitoring errors. This study used functional near-infrared spectroscopy to measure behavioral adaptations induced by VPAT and identify activated cortical areas. The results suggest that VPAT may induce behavioral adaptation through modulation of the dorsal attentional network.
SCIENTIFIC REPORTS
(2022)
Article
Multidisciplinary Sciences
Eun Bin Cho, Daegyeom Kim, ByeongChang Jeong, Jong Hwa Shin, Yeon Hak Chung, Sung Tae Kim, Byoung Joon Kim, Cheol E. Han, Ju-Hong Min
Summary: This study compared the alterations of white matter connectivity between multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and healthy controls (HC). The results showed that both MS and NMOSD groups had disrupted white matter networks compared to HC, and these alterations were associated with clinical parameters.
SCIENTIFIC REPORTS
(2022)
Article
Cardiac & Cardiovascular Systems
Artemis Zavaliangos-Petropulu, Bethany Lo, Miranda R. Donnelly, Nicolas Schweighofer, Keith Lohse, Neda Jahanshad, Giuseppe Barisano, Nerisa Banaj, Michael R. Borich, Lara A. Boyd, Cathrin M. Buetefisch, Winston D. Byblow, Jessica M. Cassidy, Charalambos C. Charalambous, Adriana B. Conforto, Julie A. DiCarlo, Adrienne N. Dula, Natalia Egorova-Brumley, Mark R. Etherton, Wuwei Feng, Kelene A. Fercho, Fatemeh Geranmayeh, Colleen A. Hanlon, Kathryn S. Hayward, Brenton Hordacre, Steven A. Kautz, Mohamed Salah Khlif, Hosung Kim, Amy Kuceyeski, David J. Lin, Jingchun Liu, Martin Lotze, Bradley J. MacIntosh, John L. Margetis, Feroze B. Mohamed, Fabrizio Piras, Ander Ramos-Murguialday, Kate P. Revill, Pamela S. Roberts, Andrew D. Robertson, Heidi M. Schambra, Na Jin Seo, Mark S. Shiroishi, Cathy M. Stinear, Surjo R. Soekadar, Gianfranco Spalletta, Myriam Taga, Wai Kwong Tang, Gregory T. Thielman, Daniela Vecchio, Nick S. Ward, Lars T. Westlye, Emilio Werden, Carolee Winstein, George F. Wittenberg, Steven L. Wolf, Kristin A. Wong, Chunshui Yu, Amy Brodtmann, Steven C. Cramer, Paul M. Thompson, Sook-Lei Liew
Summary: This study identified novel associations between chronic poststroke sensorimotor impairments and ipsilesional hippocampal volume, which may be stronger in women.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Clinical Neurology
Seungwoo Cha, ByeongChang Jeong, Myungwon Choi, Sohyun Kwon, Stephanie Hyeyoung Lee, Nam-Jong Paik, Won-Seok Kim, Cheol E. E. Han
Summary: This study identified white matter tracts associated with USN in patients with subcortical stroke without cortical involvement. Our findings support that USN may result from damage to white matter pathways.
FRONTIERS IN NEUROLOGY
(2022)
Article
Neurosciences
Giordano Marcio Gatinho Bonuzzi, Flavio Henrique Bastos, Nicolas Schweighofer, Eric Wade, Carolee Joyce Winstein, Camila Torriani-Pasin
Summary: The study investigated the effects of cardiovascular exercise on implicit motor learning of stroke survivors and neurotypical adults. It found that there was no benefit to motor learning from moderate-intensity exercise, and exercise performed before practice impaired encoding in adults and attenuated retention performance in stroke survivors.
EXPERIMENTAL BRAIN RESEARCH
(2023)
Proceedings Paper
Engineering, Electrical & Electronic
Seoyeon Choi, Dong Geun Park, Min Jung Kim, Seain Bang, Jungchun Kim, Seunghee Jin, Ki Seok Huh, Donghyun Kim, Sanghyeok Kim, Inkyu Yoon, Jerome Mitard, Cheol E. Han, Jae Woo Lee
Summary: This paper proposes an automatic V-th extraction method using machine learning. Various Vth extraction methods have been suggested for different types of FETs. Finding an appropriate extraction method for each device requires a significant amount of time and effort, and the estimation of V-th can vary depending on the researcher's insight. These issues are addressed through the use of an objective evaluation method using machine learning. The final model utilizes kNN regression and normalizes both V-G and I-D.
2023 7TH IEEE ELECTRON DEVICES TECHNOLOGY & MANUFACTURING CONFERENCE, EDTM
(2023)
Article
Engineering, Biomedical
Natalia Sanchez, Nicolas Schweighofer, James M. Finley
Summary: Step length asymmetry (SLA) is common in stroke survivors, with different factors explaining between-subjects and within-subjects variances in SLA. The direction of SLA is heterogeneous, likely due to different impairments. Common predictors between-subjects were identified to explain within-subjects variance in SLA, showing that relationships explaining between-subjects variance may not account for within-subjects stride-by-stride variance in SLA.
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING
(2021)