A high-throughput screen of real-time ATP levels in individual cells reveals mechanisms of energy failure

Coenzyme Q biosynthesis in health and disease

(2016) Manuel Jesús Acosta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response

(2016) Britt Adamson et al.   CELL

A Genome-wide CRISPR Death Screen Identifies Genes Essential for Oxidative Phosphorylation

(2016) Jason D. Arroyo et al.   Cell Metabolism

Mammalian mitochondrial ribosomal small subunit (MRPS) genes: A putative role in human disease

(2016) Gopal Gopisetty et al.   GENE

Skeletal muscle disorders of glycogenolysis and glycolysis

(2016) Richard Godfrey et al.   Nature Reviews Neurology

Hypoxia as a therapy for mitochondrial disease

(2016) I. H. Jain et al.   SCIENCE

The CoQH2/CoQ Ratio Serves as a Sensor of Respiratory Chain Efficiency

(2016) Adela Guarás et al.   Cell Reports

A Comprehensive Genomic Analysis Reveals the Genetic Landscape of Mitochondrial Respiratory Chain Complex Deficiencies

(2016) Masakazu Kohda et al.   PLoS Genetics

Evolutionary Inference across Eukaryotes Identifies Specific Pressures Favoring Mitochondrial Gene Retention

(2016) Iain G. Johnston et al.   Cell Systems

Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging

(2015) Assaf Ben-Meir et al.   AGING CELL

Mitochondrial ribosome assembly in health and disease

(2015) Dasmanthie De Silva et al.   CELL CYCLE

Central Role of Mic10 in the Mitochondrial Contact Site and Cristae Organizing System

(2015) Maria Bohnert et al.   Cell Metabolism

Methyltransferase-like 17 physically and functionally interacts with estrogen receptors

(2015) Peiyun Du et al.   IUBMB LIFE

The Role of Mitochondrially Derived ATP in Synaptic Vesicle Recycling

(2015) Divya Pathak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitofusin 2 is required to maintain mitochondrial coenzyme Q levels

(2015) Arnaud Mourier et al.   JOURNAL OF CELL BIOLOGY

Treatment options for lactic acidosis and metabolic crisis in children with mitochondrial disease

(2015) Katharina Danhauser et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Dynamin-related protein 1 is required for normal mitochondrial bioenergetic and synaptic function in CA1 hippocampal neurons

(2015) L Y Shields et al.   Cell Death & Disease

Suppression of Mic60 compromises mitochondrial transcription and oxidative phosphorylation

(2015) Rui-Feng Yang et al.   Scientific Reports

Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

(2014) Luke A. Gilbert et al.   CELL

Treatment of Mitochondrial Disorders

(2014) Gregory M. Enns   JOURNAL OF CHILD NEUROLOGY

A Mitochondrial RNAi Screen Defines Cellular Bioenergetic Determinants and Identifies an Adenylate Kinase as a Key Regulator of ATP Levels

(2014) Nathan J. Lanning et al.   Cell Reports

Energy Failure

(2013) Divya Pathak et al.   ANNALS OF NEUROLOGY

The role of mitochondrial function and cellular bioenergetics in ageing and disease

(2013) M.D. Brand et al.   BRITISH JOURNAL OF DERMATOLOGY

CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes

(2013) Luke A. Gilbert et al.   CELL

A guide to diagnosis and treatment of Leigh syndrome

(2013) F. Baertling et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Tumor glycolysis as a target for cancer therapy: progress and prospects

(2013) Shanmugasundaram Ganapathy-Kanniappan et al.   Molecular Cancer

Integrated platform for genome-wide screening and construction of high-density genetic interaction maps in mammalian cells

(2013) M. Kampmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small is fast: astrocytic glucose and lactate metabolism at cellular resolution

(2013) L. F. Barros et al.   Frontiers in Cellular Neuroscience

Inhibition of oxidative stress by coenzyme Q10 increases mitochondrial mass and improves bioenergetic function in optic nerve head astrocytes

(2013) Y H Noh et al.   Cell Death & Disease

The many roles of the conserved eukaryotic Paf1 complex in regulating transcription, histone modifications, and disease states

(2012) Brett N. Tomson et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

CoQ10 deficiencies and MNGIE: Two treatable mitochondrial disorders

(2012) Michio Hirano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Improving FRET dynamic range with bright green and red fluorescent proteins

(2012) Amy J Lam et al.   NATURE METHODS

Monogenic Mitochondrial Disorders

(2012) Werner J.H. Koopman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mitochondrial dynamics in neurodegeneration

(2012) Kie Itoh et al.   TRENDS IN CELL BIOLOGY

Ca2+Regulation of Mitochondrial ATP Synthesis Visualized at the Single Cell Level

(2011) Masahiro Nakano et al.   ACS Chemical Biology

Genetically Encoded Fluorescent Sensors for Intracellular NADH Detection

(2011) Yuzheng Zhao et al.   Cell Metabolism

The involvement of Importin-β and peroxiredoxin-6005 in mitochondrial biogenesis

(2011) Zoltan Villanyi et al.   MECHANISMS OF DEVELOPMENT

A randomized trial of coenzyme Q10in mitochondrial disorders

(2010) Elisa I. Glover et al.   MUSCLE & NERVE

Visualization of ATP levels inside single living cells with fluorescence resonance energy transfer-based genetically encoded indicators

(2009) H. Imamura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple Nuclear Localization Signals Function in the Nuclear Import of the Transcription Factor Nrf2

(2008) Melanie Theodore et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Optical Reporters for the Conformation of  -Synuclein Reveal a Specific Interaction with Mitochondria

(2008) K. Nakamura et al.   JOURNAL OF NEUROSCIENCE

Improving the photostability of bright monomeric orange and red fluorescent proteins

(2008) Nathan C Shaner et al.   NATURE METHODS

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

The role of oxygen availability in embryonic development and stem cell function

(2008) M. Celeste Simon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mitochondrial copper(I) transfer from Cox17 to Sco1 is coupled to electron transfer

(2008) L. Banci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA