Metabolic Erosion Primarily Through Mutation Accumulation, and Not Tradeoffs, Drives Limited Evolution of Substrate Specificity in Escherichia coli

A latent capacity for evolutionary innovation through exaptation in metabolic systems

(2013) Aditya Barve et al.   NATURE

Development of an Optimized Medium, Strain and High-Throughput Culturing Methods for Methylobacterium extorquens

(2013) Nigel F. Delaney et al.   PLoS One

Normal Mutation Rate Variants Arise in a Mutator (Mut S) Escherichia coli Population

(2013) María-Carmen Turrientes et al.   PLoS One

The Ability of Flux Balance Analysis to Predict Evolution of Central Metabolism Scales with the Initial Distance to the Optimum

(2013) William R. Harcombe et al.   PLoS Computational Biology

The Environment Affects Epistatic Interactions to Alter the Topology of an Empirical Fitness Landscape

(2013) Kenneth M. Flynn et al.   PLoS Genetics

Multiple long-term, experimentally-evolved populations of Escherichia coli acquire dependence upon citrate as an iron chelator for optimal growth on glucose

(2012) Nicholas Leiby et al.   BMC EVOLUTIONARY BIOLOGY

The Evolution of Low Mutation Rates in Experimental Mutator Populations of Saccharomyces cerevisiae

(2012) Michael J. McDonald et al.   CURRENT BIOLOGY

Genomic analysis of a key innovation in an experimental Escherichia coli population

(2012) Zachary D. Blount et al.   NATURE

Ecological and evolutionary dynamics of coexisting lineages during a long-term experiment with Escherichia coli

(2012) M. Le Gac et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutation rate dynamics in a bacterial population reflect tension between adaptation and genetic load

(2012) S. Wielgoss et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Understanding specialism when the jack of all trades can be the master of all

(2012) S. Remold   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Repeated, Selection-Driven Genome Reduction of Accessory Genes in Experimental Populations

(2012) Ming-Chun Lee et al.   PLoS Genetics

Negative Epistasis Between Beneficial Mutations in an Evolving Bacterial Population

(2011) A. I. Khan et al.   SCIENCE

What is flux balance analysis?

(2010) Jeffrey D Orth et al.   NATURE BIOTECHNOLOGY

ASYMMETRIC, BIMODAL TRADE-OFFS DURING ADAPTATION OFMETHYLOBACTERIUMTO DISTINCT GROWTH SUBSTRATES

(2009) Ming-Chun Lee et al.   EVOLUTION

Genome evolution and adaptation in a long-term experiment with Escherichia coli

(2009) Jeffrey E. Barrick et al.   NATURE

Fast Growth Increases the Selective Advantage of a Mutation Arising Recurrently during Evolution under Metal Limitation

(2009) Hsin-Hung Chou et al.   PLoS Genetics

Death and cannibalism in a seasonal environment facilitate bacterial coexistence

(2008) Daniel E. Rozen et al.   ECOLOGY LETTERS

Historical contingency and the evolution of a key innovation in an experimental population of Escherichia coli

(2008) Z. D. Blount et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA