PI3K Signaling and Stat92E Converge to Modulate Glial Responsiveness to Axonal Injury

The c-Jun kinase signaling cascade promotes glial engulfment activity through activation of draper and phagocytic function

(2013) J M MacDonald et al.   CELL DEATH AND DIFFERENTIATION

Src kinases mediate the interaction of the apical determinant Bazooka/PAR3 with STAT92E and increase signalling efficiency in Drosophila ectodermal cells

(2013) S. Sotillos et al.   DEVELOPMENT

Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways

(2013) Won-Suk Chung et al.   NATURE

Heterogeneity of reactive astrocytes

(2013) Mark A. Anderson et al.   NEUROSCIENCE LETTERS

The potential role of JAK2/STAT3 pathway on the anti-apoptotic effect of recombinant human erythropoietin (rhEPO) after experimental traumatic brain injury of rats

(2011) Jinbing Zhao et al.   CYTOKINE

JAK/STAT and the GATA factor Pannier control hemocyte maturation and differentiation in Drosophila

(2011) Svetlana Minakhina et al.   DEVELOPMENTAL BIOLOGY

Neuronal Death Induced by Nanomolar Amyloid β Is Mediated by Primary Phagocytosis of Neurons by Microglia

(2011) Urte Neniskyte et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

STAT3 signaling after traumatic brain injury

(2011) Anthony A. Oliva et al.   JOURNAL OF NEUROCHEMISTRY

Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination

(2011) Stephen P J Fancy et al.   NATURE NEUROSCIENCE

Cytokine signaling through the JAK/STAT pathway is required for long-term memory in Drosophila

(2011) T. Copf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An efficient approach to isolate STAT regulated enhancers uncovers STAT92E fundamental role in Drosophila tracheal development

(2010) Sol Sotillos et al.   DEVELOPMENTAL BIOLOGY

Characterization of a dominant-active STAT that promotes tumorigenesis in Drosophila

(2010) Laura A. Ekas et al.   DEVELOPMENTAL BIOLOGY

chinmo Is a Functional Effector of the JAK/STAT Pathway that Regulates Eye Development, Tumor Formation, and Stem Cell Self-Renewal in Drosophila

(2010) Maria Sol Flaherty et al.   DEVELOPMENTAL CELL

Negative regulation of Drosophila JAK-STAT signalling by endocytic trafficking

(2010) O. M. Vidal et al.   JOURNAL OF CELL SCIENCE

A critical look at connectomics

(2010)   NATURE NEUROSCIENCE

Reactive astrocytes as therapeutic targets for CNS disorders

(2010) Mary E. Hamby et al.   Neurotherapeutics

A Short Receptor Downregulates JAK/STAT Signalling to Control the Drosophila Cellular Immune Response

(2010) Rami Makki et al.   PLOS BIOLOGY

Drosophila Intestinal Response to Bacterial Infection: Activation of Host Defense and Stem Cell Proliferation

(2009) Nicolas Buchon et al.   Cell Host & Microbe

Ensheathing Glia Function as Phagocytes in the Adult Drosophila Brain

(2009) J. Doherty et al.   JOURNAL OF NEUROSCIENCE

A Cdc42 Activation Cycle Coordinated by PI 3-Kinase during Fc Receptor-mediated Phagocytosis

(2009) Peter Beemiller et al.   MOLECULAR BIOLOGY OF THE CELL

Glial precursors clear sensory neuron corpses during development via Jedi-1, an engulfment receptor

(2009) Hsiao-Huei Wu et al.   NATURE NEUROSCIENCE

Genetic Interactions between the Drosophila Tumor Suppressor Gene ept and the stat92E Transcription Factor

(2009) M. Melissa Gilbert et al.   PLoS One

Debris clearance by microglia: an essential link between degeneration and regeneration

(2008) H. Neumann et al.   BRAIN

Plasticity of Drosophila Stat DNA binding shows an evolutionary basis for Stat transcription factor preferences

(2008) María Luisa Rivas et al.   EMBO REPORTS

The JAK/STAT pathway positively regulates DPP signaling in theDrosophilagermline stem cell niche

(2008) Liwei Wang et al.   JOURNAL OF CELL BIOLOGY

JAK/STAT3 pathway is activated in spinal cord microglia after peripheral nerve injury and contributes to neuropathic pain development in rat

(2008) Elisa Dominguez et al.   JOURNAL OF NEUROCHEMISTRY

Interleukin-6 is required for the early induction of glial fibrillary acidic protein in Schwann cells during Wallerian degeneration

(2008) Hyun Kyoung Lee et al.   JOURNAL OF NEUROCHEMISTRY

Endothelin-1 Regulates Astrocyte Proliferation and Reactive Gliosis via a JNK/c-Jun Signaling Pathway

(2008) A. Gadea et al.   JOURNAL OF NEUROSCIENCE

Microglia Cells Protect Neurons by Direct Engulfment of Invading Neutrophil Granulocytes: A New Mechanism of CNS Immune Privilege

(2008) J. Neumann et al.   JOURNAL OF NEUROSCIENCE

STAT3 is a Critical Regulator of Astrogliosis and Scar Formation after Spinal Cord Injury

(2008) J. E. Herrmann et al.   JOURNAL OF NEUROSCIENCE

Draper-dependent glial phagocytic activity is mediated by Src and Syk family kinase signalling

(2008) Jennifer S. Ziegenfuss et al.   NATURE

The Mystery and Magic of Glia: A Perspective on Their Roles in Health and Disease

(2008) Ben A. Barres   NEURON

Microglial clearance function in health and disease

(2008) I. Napoli et al.   NEUROSCIENCE

STAT92E is a positive regulator of Drosophila inhibitor of apoptosis 1 (DIAP/1) and protects against radiation-induced apoptosis

(2008) A. Betz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA