Molecular Remodeling of Tip Links Underlies Mechanosensory Regeneration in Auditory Hair Cells

Sliding Adhesion Confers Coherent Motion to Hair Cell Stereocilia and Parallel Gating to Transduction Channels

(2013) K. D. Karavitaki et al.   JOURNAL OF NEUROSCIENCE

Noddy, a Mouse Harboring a Missense Mutation in Protocadherin-15, Reveals the Impact of Disrupting a Critical Interaction Site between Tip-Link Cadherins in Inner Ear Hair Cells

(2013) R. Geng et al.   JOURNAL OF NEUROSCIENCE

TMHS Is an Integral Component of the Mechanotransduction Machinery of Cochlear Hair Cells

(2012) Wei Xiong et al.   CELL

Structure of a force-conveying cadherin bond essential for inner-ear mechanotransduction

(2012) Marcos Sotomayor et al.   NATURE

Thinking outside the cell: how cadherins drive adhesion

(2012) Julia Brasch et al.   TRENDS IN CELL BIOLOGY

Regulation of PCDH15 function in mechanosensory hair cells by alternative splicing of the cytoplasmic domain

(2011) S. W. Webb et al.   DEVELOPMENT

Mechanotransduction in mouse inner ear hair cells requires transmembrane channel–like genes

(2011) Yoshiyuki Kawashima et al.   JOURNAL OF CLINICAL INVESTIGATION

Simulation of the Response of the Inner Hair Cell Stereocilia Bundle to an Acoustical Stimulus

(2011) Sonya T. Smith et al.   PLoS One

Usher type 1G protein sans is a critical component of the tip-link complex, a structure controlling actin polymerization in stereocilia

(2011) E. Caberlotto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrating the biophysical and molecular mechanisms of auditory hair cell mechanotransduction

(2011) Anthony W. Peng et al.   Nature Communications

Asymmetric distribution of cadherin 23 and protocadherin 15 in the kinocilial links of avian sensory hair cells

(2010) Richard J. Goodyear et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Development and Regeneration of Sensory Transduction in Auditory Hair Cells Requires Functional Interaction Between Cadherin-23 and Protocadherin-15

(2010) A. Lelli et al.   JOURNAL OF NEUROSCIENCE

Structural Determinants of Cadherin-23 Function in Hearing and Deafness

(2010) Marcos Sotomayor et al.   NEURON

Tonotopic Gradient in the Developmental Acquisition of Sensory Transduction in Outer Hair Cells of the Mouse Cochlea

(2009) Andrea Lelli et al.   JOURNAL OF NEUROPHYSIOLOGY

Fast Adaptation and Ca2+ Sensitivity of the Mechanotransducer Require Myosin-XVa in Inner But Not Outer Cochlear Hair Cells

(2009) R. Stepanyan et al.   JOURNAL OF NEUROSCIENCE

Localization of inner hair cell mechanotransducer channels using high-speed calcium imaging

(2009) Maryline Beurg et al.   NATURE NEUROSCIENCE

Harmonin Mutations Cause Mechanotransduction Defects in Cochlear Hair Cells

(2009) Nicolas Grillet et al.   NEURON

The Allosteric Role of the Ca2+ Switch in Adhesion and Elasticity of C-Cadherin

(2008) Marcos Sotomayor et al.   BIOPHYSICAL JOURNAL

Stereocilin-deficient mice reveal the origin of cochlear waveform distortions

(2008) Elisabeth Verpy et al.   NATURE