Journal
PATHOGENS AND GLOBAL HEALTH
Volume 108, Issue 4, Pages 173-178Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1179/2047773214Y.0000000139
Keywords
Malaria; Immunity; Cytokines; Inflammation
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Strong early inflammatory responses followed by a timely production of regulatory cytokines are required to control malaria parasite multiplication without inducing major host pathology. Here, we briefly examine the homeostasis of inflammatory responses to malaria parasite species with varying virulence levels and discuss how co-infections with bacteria, viruses, and helminths can modulate inflammation, either aggravating or alleviating malaria-related morbidity.
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