Drosophila as a model system to unravel the layers of innate immunity to infection

Pirk Is a Negative Regulator of the Drosophila Imd Pathway

(2014) A. Kleino et al.   JOURNAL OF IMMUNOLOGY

Drosophila Pez Acts in Hippo Signaling to Restrict Intestinal Stem Cell Proliferation

(2012) Ingrid Poernbacher et al.   CURRENT BIOLOGY

The Circadian Clock Protein Timeless Regulates Phagocytosis of Bacteria in Drosophila

(2012) Elizabeth F. Stone et al.   PLoS Pathogens

Lactobacillus plantarum Promotes Drosophila Systemic Growth by Modulating Hormonal Signals through TOR-Dependent Nutrient Sensing

(2011) Gilles Storelli et al.   Cell Metabolism

Multiple TGF-β Superfamily Signals Modulate the Adult Drosophila Immune Response

(2011) Rebecca I. Clark et al.   CURRENT BIOLOGY

Hematopoiesis at the onset of metamorphosis: terminal differentiation and dissociation of the Drosophila lymph gland

(2011) Melina Grigorian et al.   DEVELOPMENT GENES AND EVOLUTION

Pathogen and host factors are needed to provoke a systemic host response to gastrointestinal infection of Drosophila larvae by Candida albicans

(2011) M. T. Glittenberg et al.   Disease Models & Mechanisms

Low-diversity bacterial community in the gut of the fruitfly Drosophila melanogaster

(2011) Chun Nin Adam Wong et al.   ENVIRONMENTAL MICROBIOLOGY

Intestinal stem cells in the adult Drosophila midgut

(2011) Huaqi Jiang et al.   EXPERIMENTAL CELL RESEARCH

Negative Regulation by Amidase PGRPs Shapes the Drosophila Antibacterial Response and Protects the Fly from Innocuous Infection

(2011) Juan C. Paredes et al.   IMMUNITY

Relative Roles of the Cellular and Humoral Responses in the Drosophila Host Defense against Three Gram-Positive Bacterial Infections

(2011) Nadine T. Nehme et al.   PLoS One

Genetic evidence for a protective role of the peritrophic matrix against intestinal bacterial infection in Drosophila melanogaster

(2011) T. Kuraishi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Illuminating the landscape of host-pathogen interactions with the bacterium Listeria monocytogenes

(2011) P. Cossart   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drosophila Microbiome Modulates Host Developmental and Metabolic Homeostasis via Insulin Signaling

(2011) S. C. Shin et al.   SCIENCE

Bacterial Communities of Diverse Drosophila Species: Ecological Context of a Host–Microbe Model System

(2011) James Angus Chandler et al.   PLoS Genetics

Wall Teichoic Acids of Staphylococcus aureus Limit Recognition by the Drosophila Peptidoglycan Recognition Protein-SA to Promote Pathogenicity

(2011) Magda L. Atilano et al.   PLoS Pathogens

An in vivo RNA interference screen identifies gene networks controlling Drosophila melanogaster blood cell homeostasis.

(2010) Amelie Avet-Rochex et al.   BMC DEVELOPMENTAL BIOLOGY

Transcriptional targets of Drosophila JAK/STAT pathway signalling as effectors of haematopoietic tumour formation

(2010) Samira Bina et al.   EMBO REPORTS

Genome-Wide RNA Interference in Drosophila Cells Identifies G Protein-Coupled Receptor Kinase 2 as a Conserved Regulator of NF- B Signaling

(2010) S. Valanne et al.   JOURNAL OF IMMUNOLOGY

Pellino enhances innate immunity in Drosophila

(2010) Amirhossein Haghayeghi et al.   MECHANISMS OF DEVELOPMENT

The POU Transcription Factor Drifter/Ventral veinless Regulates Expression of Drosophila Immune Defense Genes

(2010) A. Junell et al.   MOLECULAR AND CELLULAR BIOLOGY

Caspase-Mediated Cleavage, IAP Binding, and Ubiquitination: Linking Three Mechanisms Crucial for Drosophila NF-κB Signaling

(2010) Nicholas Paquette et al.   MOLECULAR CELL

FOXO-dependent regulation of innate immune homeostasis

(2010) Thomas Becker et al.   NATURE

Endocytic pathway is required for Drosophila Toll innate immune signaling

(2010) H.-R. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role for Sumoylation in Systemic Inflammation and Immune Homeostasis in Drosophila Larvae

(2010) Indira Paddibhatla et al.   PLoS Pathogens

Pathogen Entrapment by Transglutaminase—A Conserved Early Innate Immune Mechanism

(2010) Zhi Wang et al.   PLoS Pathogens

Cytokine/Jak/Stat Signaling Mediates Regeneration and Homeostasis in the Drosophila Midgut

(2009) Huaqi Jiang et al.   CELL

The Drosophila Ubiquitin-Specific Protease dUSP36/Scny Targets IMD to Prevent Constitutive Immune Signaling

(2009) Dominique Thevenon et al.   Cell Host & Microbe

The Drosophila Hindgut Lacks Constitutively Active Adult Stem Cells but Proliferates in Response to Tissue Damage

(2009) Donald T. Fox et al.   Cell Stem Cell

Regulation of DUOX by the Gαq-Phospholipase Cβ-Ca2+ Pathway in Drosophila Gut Immunity

(2009) Eun-Mi Ha et al.   DEVELOPMENTAL CELL

Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in Drosophila

(2009) N. Buchon et al.   GENES & DEVELOPMENT

Three Pairs of Protease-Serpin Complexes Cooperatively Regulate the Insect Innate Immune Responses

(2009) Rui Jiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The N-terminal Domain ofDrosophilaGram-negative Binding Protein 3 (GNBP3) Defines a Novel Family of Fungal Pattern Recognition Receptors

(2009) Yumiko Mishima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteolytic Cascade for the Activation of the Insect Toll Pathway Induced by the Fungal Cell Wall Component

(2009) Kyung-Baeg Roh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Toll-dependent antimicrobial responses in Drosophila larval fat body require Spätzle secreted by haemocytes

(2009) Alice K. H. Shia et al.   JOURNAL OF CELL SCIENCE

Identification of Lipoteichoic Acid as a Ligand for Draper in the Phagocytosis of Staphylococcus aureus by Drosophila Hemocytes

(2009) Y. Hashimoto et al.   JOURNAL OF IMMUNOLOGY

Genetic Ablation of Drosophila Phagocytes Reveals Their Contribution to Both Development and Resistance to Bacterial Infection

(2009) Arnaud Defaye et al.   Journal of Innate Immunity

Coordination of multiple dual oxidase–regulatory pathways in responses to commensal and infectious microbes in drosophila gut

(2009) Eun-Mi Ha et al.   NATURE IMMUNOLOGY

The Imd Pathway Is Involved in Antiviral Immune Responses in Drosophila

(2009) Alexandre Costa et al.   PLoS One

Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes

(2009) D. Erturk-Hasdemir et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A single modular serine protease integrates signals from pattern-recognition receptors upstream of the Drosophila Toll pathway

(2009) N. Buchon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Elimination of plasmatocytes by targeted apoptosis reveals their role in multiple aspects of the Drosophila immune response

(2009) B. Charroux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Wide RNAi Screen Identifies Genes Involved in Intestinal Pathogenic Bacterial Infection

(2009) S. J. F. Cronin et al.   SCIENCE

The Role of Anorexia in Resistance and Tolerance to Infections in Drosophila

(2009) Janelle S. Ayres et al.   PLOS BIOLOGY

PIMS Modulates Immune Tolerance by Negatively Regulating Drosophila Innate Immune Signaling

(2008) Nouara Lhocine et al.   Cell Host & Microbe

A Misexpression Screen to Identify Regulators of Drosophila Larval Hemocyte Development

(2008) M. Stofanko et al.   GENETICS

Structural Insight into the Mechanism of Activation of the Toll Receptor by the Dimeric Ligand Spätzle

(2008) Monique Gangloff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sensing of 'danger signals' and pathogen-associated molecular patterns defines binary signaling pathways 'upstream' of Toll

(2008) Laure El Chamy et al.   NATURE IMMUNOLOGY

Autophagic control of listeria through intracellular innate immune recognition in drosophila

(2008) Tamaki Yano et al.   NATURE IMMUNOLOGY

Peptidoglycan recognition protein-SD provides versatility of receptor formation in Drosophila immunity

(2008) L. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DEAF-1 regulates immunity gene expression in Drosophila

(2008) D. E. Reed et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antimicrobial Defense and Persistent Infection in Insects

(2008) E. R. Haine et al.   SCIENCE

Innate Immune Homeostasis by the Homeobox Gene Caudal and Commensal-Gut Mutualism in Drosophila

(2008) J.-H. Ryu et al.   SCIENCE

A Signaling Protease Required for Melanization in Drosophila Affects Resistance and Tolerance of Infections

(2008) Janelle S Ayres et al.   PLOS BIOLOGY