Article
Public, Environmental & Occupational Health
Dina Hussein Yamin, Azlan Husin, Azian Harun
Summary: Catheter-related bloodstream infection, caused by various nosocomial pathogens, is an important healthcare-associated infection, with Candida parapsilosis emerging as a crucial causative agent in the last two decades. Factors such as ICU admission were found to be significantly associated with non-CRBSI, while TPN was significantly positively associated with CRBSI. Patients admitted in ICU were less likely to develop C. parapsilosis CRBSI, while patients receiving TPN were more likely to have C. parapsilosis CRBSI compared to the non-CRBSI group.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Nursing
Eman Arafa Hassan, Suad Elsayed Abdelmotalb Elsaman
Summary: Compliance with the ventilator bundle was found to be associated with a decreased risk of ventilator-associated events (VAEs) occurrence. Mechanically ventilated patients had a lower likelihood of experiencing VAEs when receiving the ventilator bundle.
Article
Immunology
Vu Quoc Dat, Lam Minh Yen, Huynh Thi Loan, Vu Dinh Phu, Nguyen Thien Binh, Ronald B. Geskus, Dong Huu Khanh Trinh, Nguyen Thi Hoang Mai, Nguyen Hoan Phu, Nguyen Phu Huong Lan, Tran Phuong Thuy, Nguyen Vu Trung, Nguyen Trung Cap, Dao Tuyet Trinh, Nguyen Thi Hoa, Nguyen Thi Thu Van, Vy Thi Thu Luan, Tran Thi Quynh Nhu, Hoang Bao Long, Nguyen Thi Thanh Ha, Ninh Thi Thanh Van, James Campbell, Ehsan Ahmadnia, Evelyne Kestelyn, Duncan Wyncoll, Guy E. Thwaites, Nguyen Van Hao, Le Thanh Chien, Nguyen Van Kinh, Nguyen Van Vinh Chau, H. Rogier van Doorn, C. Louise Thwaites, Behzad Nadjm
Summary: The study found that continuous cuff pressure control (CPC) using an automated electronic device did not reduce the incidence of ventilator-associated respiratory infection (VARI) in intubated patients compared to intermittent CPC.
CLINICAL INFECTIOUS DISEASES
(2022)
Article
Medicine, General & Internal
Seok Jun Mun, Si-Ho Kim, Kyungmin Huh, Sun Young Cho, Cheol-In Kang, Doo Ryeon Chung, Kyong Ran Peck
Summary: This study found that in patients with uncomplicated S. aureus CRBSI, the risk of treatment failure may be more influenced by factors such as liver cirrhosis and other prostheses, rather than the implementation of echocardiography. Routine echocardiography might not be necessary given the low rates of adverse outcomes observed, and could be considered on an individual basis.
Article
Medicine, General & Internal
Kiyoshi Moriyama, Tadao Ando, Mariko Kotani, Joho Tokumine, Harumasa Nakazawa, Akira Motoyasu, Tomoko Yorozu
Summary: This study analyzed the factors associated with bloodstream infection in patients with central venous catheter insertions and evaluated the effectiveness of preventive measures. The study found that the duration of ICU stay, duration of catheter insertion, and APACHE II score were associated with bloodstream infection.
Article
Microbiology
Julia Laporte-Amargos, Enric Sastre, Alba Bergas, Helena Pomares, Annalisa Paviglianiti, Marisol Rodriguez-Arias, Natalia Pallares, Ana Maria Badia-Tejero, Paula Pons-Oltra, Jordi Carratala, Carlota Gudiol
Summary: This study aimed to assess the incidence, etiology, and outcomes of catheter-related bloodstream infection (CRBSI) in onco-hematological patients. The results showed that Gram-positive bacteria were the main pathogens causing infection, while the incidence of Gram-negative bacteria increased over time. Multidrug-resistant Gram-negative bacteria were also on the rise. It was also found that the non-removal of the catheter was associated with decreased survival rates.
Article
Infectious Diseases
Shinya Yamamoto, Mahoko Ikeda, Yuki Ohama, Tomohiro Sunouchi, Yasutaka Hoshino, Hiroshi Ito, Marie Yamashita, Yoshiaki Kanno, Koh Okamoto, Satoshi Yamagoe, Yoshitsugu Miyazaki, Shu Okugawa, Jun Fujishiro, Kyoji Moriya
Summary: This case report presents a bloodstream infection of Aureobasidium melanigenum in a patient with long-term catheter use. The identification of A. melanigenum proved challenging through routine microbiological testing. The patient recovered with antifungal therapy and catheter removal.
BMC INFECTIOUS DISEASES
(2022)
Article
Public, Environmental & Occupational Health
L. Badia-Cebada, J. Penafiel, J. Lopez-Contreras, V Pomar, J. A. Martinez, G. Santana, J. Cuquet, M. M. Montero, C. Hidalgo-Lopez, M. Andres, M. Gimenez, M. D. Quesada, M. Vaque, S. Iftimie, C. Gudiol, R. Perez, A. Coloma, A. Marron, P. Barrufet, M. Marimon, A. Lerida, M. Claros, M. F. Ramirez-Hidalgo, G. Garcia Pardo, M. J. Martinez, E. L. Chamarro, E. Jimenez-Martinez, A. Hornero, E. Limon, M. Lopez, E. Calbo, M. Pujol, O. Gasch
Summary: The mortality associated with CRBSI has decreased in recent years but remains high. Intervention programs should focus on ICUs and medical wards, where the incidence and mortality rates are the highest.
JOURNAL OF HOSPITAL INFECTION
(2022)
Editorial Material
Infectious Diseases
Leonard A. Mermel
Summary: Antimicrobial lock therapy is used for preventing CRBSI in patients with long-term central venous catheters. However, it does not prevent bloodstream infections in patients with short bowel syndrome that may originate from translocation.
CLINICAL MICROBIOLOGY AND INFECTION
(2023)
Review
Public, Environmental & Occupational Health
Q. Guo, Z. Lv, H. Wang, L. Song, Y. Liu, H. Chen, C. Zhou
Summary: The study compared the effectiveness of different catheter lock solutions in preventing catheter-related bloodstream infections in pediatric patients, and found that taurolidine + heparin was the most effective solution for preventing CRBSI.
JOURNAL OF HOSPITAL INFECTION
(2021)
Article
Acoustics
Takahiro Hosokawa, Kuntaro Deguchi, Haruka Takei, Yumiko Sato, Yutaka Tanami, Eiji Oguma
Summary: Ultrasound findings are useful for diagnosing CRBSI, but have low sensitivity and may not show abnormal results in some pediatric patients with CRBSI. Physicians should not exclude the diagnosis of CRBSI based solely on normal ultrasound findings, especially in patients with a central venous catheter and a positive blood culture.
JOURNAL OF ULTRASOUND IN MEDICINE
(2023)
Article
Medicine, General & Internal
Jonas Jurt, Martin Hubner, Daniel Clerc, Pauline Curchod, Mohamed A. Abd El Aziz, Dieter Hahnloser, Laurence Senn, Nicolas Demartines, Fabian Grass
Summary: The implementation of an intraoperative standardized care bundle had no impact on SSI rates. This may be explained by insufficient compliance with the individual measures.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Public, Environmental & Occupational Health
Niccolo Buetti, Mohamed Abbas, Didier Pittet, Marie-Noelle Chraiti, Valerie Sauvan, Marlieke E. A. De Kraker, Matthieu Boisson, Daniel Teixeira, Walter Zingg, Stephan Harbarth
Summary: Hand insertion of short-term peripheral venous catheters is associated with a decreased risk of infection, especially for catheters with an expected dwell time of more than 2 days.
ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL
(2022)
Article
Infectious Diseases
Andres Blanco-Di Matteo, Nuria Garcia-Fernandez, Aitziber Aguinaga Perez, Francisco Carmona-Torre, Amaya C. Oteiza, Jose Leiva, Jose Luis Del Pozo
Summary: This study aimed to prove that pre-emptive antimicrobial locks in patients at risk of bacteremia decrease infection. The results showed that patients treated with antimicrobial lock had a relative risk of bloodstream infection of 0.19 when compared with heparin lock within three months of treatment. Additionally, using antimicrobial lock for every ten catheter-critical colonizations can prevent one catheter-related bloodstream infection.
Review
Critical Care Medicine
Bert Maertens, Frances Lin, Yingyan Chen, Jordi Rello, Dimitrios Lathyris, Stijn Blot
Summary: This systematic review and meta-analysis assessed the effectiveness of continuous cuff pressure control (CCPC) in preventing ventilator-associated pneumonia (VAP). The findings suggest that the use of CCPC is associated with a reduced risk of VAP and shorter durations of mechanical ventilation and ICU stay. However, due to biases and inconsistencies in the included studies, the certainty of evidence is considered very low.
CRITICAL CARE MEDICINE
(2022)