Article
Pharmacology & Pharmacy
Muhammad Sarfraz, Ume Ruqia Tulain, Alia Erum, Nadia Shamshad Malik, Arshad Mahmood, Mansur Abdullah Sumaira, Sidra Aslam, Mansur Abdullah Sandhu, Muhammad Tayyab
Summary: The study assessed the potential of quince seed mucilage as an excipient in a graft copolymer for oral-controlled drug delivery systems. The graft copolymer was synthesized using a free radical polymerization method and various concentrations of monomers. The drug-loaded hydrogel showed sustained release patterns and improved pharmacokinetic parameters compared to a commercially available product.
Article
Agriculture, Multidisciplinary
Melekber Sulusoglu Durul, Tulay Korana Aktas
Summary: Quince is a pome fruit that belongs to the Rosaceae family and is grown in temperate climates. It is rich in bioactive compounds and holds potential in the health and pharmaceutical sectors. This study describes an in vitro propagation protocol for Cydonia oblonga cv. Esme and explores the effects of different culture media on proliferation and rooting.
TURKISH JOURNAL OF AGRICULTURE AND FORESTRY
(2023)
Article
Biochemistry & Molecular Biology
Federica Gubitosa, Daniele Fraternale, Roberta De Bellis, Andrea Gorassini, Leila Benayada, Laura Chiarantini, Maria Cristina Albertini, Lucia Potenza
Summary: The pharmacological activity of callus extract from Cydonia oblonga Mill. pulp was investigated, and it was found to have anti-inflammatory and antioxidant activities. This suggests its potential application in delaying and preventing age-related acute and chronic diseases, as well as in wound dressing treatment.
Article
Biochemistry & Molecular Biology
Shaymaa Najm Abed, Sania Bibi, Marwa Jan, Muhammad Talha, Noor Ul Islam, Muhammad Zahoor, Fakhria A. Al-Joufi
Summary: Cydonia oblonga, a medicinal plant, has potential antibacterial, antioxidant, and anti-diabetic properties in its bark extracts. Methanolic extracts showed effective antibacterial activity, especially against Staphylococcus aureus and Streptococcus pneumonia. The phytochemical composition of the extracts may lead to new antibiotic discoveries.
Article
Chemistry, Medicinal
Fatma Z. Sakhri, Naoki Adachi, Sakina Zerizer, Yusuke Ohashi, Hideshi Ikemoto, Mana Tsukada, Zahia Kabouche, Tadashi Hisamitsu, Masataka Sunagawa
Summary: This study demonstrates the antidepressant effect of Cydonia oblonga fruit extract by enhancing hippocampal neurogenesis in a rat model of depression. The extract successfully suppressed physiological and behavioral markers of chronic stress, prevented structural abnormalities in the hippocampus, and improved mood function in normal rats.
PHYTOTHERAPY RESEARCH
(2021)
Article
Food Science & Technology
Roberta De Bellis, Laura Chiarantini, Lucia Potenza, Andrea Gorassini, Giancarlo Verardo, Rossella De Marco, Leila Benayada, Vilberto Stocchi, Maria Cristina Albertini, Daniele Fraternale
Summary: This study developed an innovative method for extracting secondary metabolites from quince callus cultures and analyzed its composition and activities using various techniques. The extract exhibited good antioxidant activity and strong inhibition of alpha-glucosidase and lipase, indicating its potential for developing nutraceutical approaches for managing hyperglycemia and dyslipidemia.
JOURNAL OF FUNCTIONAL FOODS
(2022)
Review
Integrative & Complementary Medicine
Atefeh Amerizadeh, Golnaz Vaseghi, Nazgol Esmaeilian, Sedigheh Asgary
Summary: This review provides a comprehensive summary of the botany, phytochemistry, and pharmacology of Cydonia oblonga Miller (quince), with a focus on its impact on cardiovascular risk factors such as diabetes, blood pressure, lipid profile, and body weight. The studies reviewed suggest that various quince extracts can have positive effects on these factors, similar to the effects of conventional medications for hypertension and hyperlipidemia. However, the effect of quince on insulin levels remains inconclusive. These findings support further research on the cardiovascular benefits of quince consumption in humans.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
(2022)
Article
Biochemistry & Molecular Biology
Katarzyna Najman, Sylwia Adrian, Anna Sadowska, Katarzyna Swiader, Ewelina Hallmann, Krzysztof Buczak, Bozena Waszkiewicz-Robak, Arkadiusz Szterk
Summary: Quince is a widely cultivated plant known for its valuable nutritional and healing properties. The fruit is not suitable for direct consumption due to its high hardness and sour taste, but it is commonly used in fruit processing, such as jam and juice production. This research aimed to determine the impact of technological treatments on the physicochemical and bioactive properties of quince fruit.
Review
Horticulture
Mitra Mirabdulbaghi, Mahyar Tavusi, Hamid Abdollahi, Reza Zarghami
Summary: This study investigated the effect of soil lime stress on the nutritional composition and quality parameters of quince. The results showed that soil lime stress induced significant changes in the fruit nutrient content and quality parameters, with variations depending on the cultivar type and the cold storage time.
Article
Chemistry, Medicinal
Bingqing Chi, Xilong Liang, Lihua Wang, Yifei Bian, Meng Zhang, Zhixin Tang, Danyang Wang, Zhenhua Tian
Summary: This study investigated the anti-diabetic activity and mechanism of Cydonia Oblonga Mill. fruit. Analysis of its chemical compositions revealed the presence of various active components. Quercetin exhibited strong inhibitory activity, while other components showed different degrees of inhibitory activity. Furthermore, these active components were able to restore the gene expression levels of cells damaged by high glucose.
Article
Agronomy
Katarzyna Najman, Sylwia Adrian, Ewelina Hallmann, Anna Sadowska, Krzysztof Buczak, Bozena Waszkiewicz-Robak, Arkadiusz Szterk
Summary: The quince is increasing in popularity due to its valuable bioactive properties and high health-promoting potential for preventing free radical diseases. However, its high hardness, bitterness, and astringency mean that it is rarely eaten fresh and is more often consumed in the form of preserves or as dried additives. The dehydration process significantly changes the physicochemical properties, content of bioactive compounds, and antioxidant properties of quinces.
Article
Food Science & Technology
Hyun Sook Lee, Young Eun Jeon, Jae In Jung, So Mi Kim, Su Hee Hong, Jaehak Lee, Jung Soon Hwang, Myeong Oh Hwang, Kisung Kwon, Eun Ji Kim
Summary: COME may be used as an anti-obesity agent by activating AMPK to inhibit adipogenesis and promote lipolysis and fatty acid oxidation.
JOURNAL OF FUNCTIONAL FOODS
(2022)
Article
Multidisciplinary Sciences
Aysenur Soyturk, Fatima Sen, Ali Tevfik Uncu, Ibrahim Celik, Ayse Ozgur Uncu
Summary: This study successfully assembled the first draft genome of quince using sequencing technology, identified a large number of protein-coding genes, and predicted numerous pre-miRNA coding loci, laying the foundation for functional genomic research in quince.
SCIENTIFIC REPORTS
(2021)
Article
Plant Sciences
Diana Melo Ferreira, Natalia M. de Oliveira, Lara Lopes, Jorge Machado, Maria Beatriz Oliveira
Summary: This study conducted quantitative and qualitative analyses of quince leaves in Portugal, revealing their rich content of minerals and organic compounds. Quince leaves exhibit beneficial physiological properties in cardiovascular, pulmonary, and immune defenses, making them an excellent supplement for complementary therapy.
Article
Pharmacology & Pharmacy
Muhammad Shafeeq Ur Rahman, Muhammad Saleem, Alamgeer, Mater Hussen Mahnashi, Yahya Saeed Alqahtani, Ali Omar Alqarni, Bandar Ali Alyami, Muhammad Naveed Mushtaq, Sumera Qasim
Summary: The study found that the extract from Cydonia oblonga seeds can reduce blood pressure in rats, especially those with high cholesterol and glucose-fed hypertension. The optimal dose of the extract was determined to be 600mg/kg in rats, while the safe dose in mice was found to be 4g/kg. Additionally, the extract was observed to decrease low density cholesterol levels in rats without significant alterations in blood chemistry.
PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2021)
Article
Chemistry, Physical
Marcilene Machado dos Santos Sarah, Renato de Mello Prado, Gelza Carliane Marques Teixeira, Jonas Pereira de Souza Junior, Robson Luis Silva de Medeiros, Rafael Ferreira Barreto
Summary: The application of silicon improved water use efficiency, chlorophyll and carotenoid contents, and dry matter production in potassium-deficient maize plants, with a more noticeable effect when applied via the roots.
Article
Agronomy
Gelza Carliane Marques Teixeira, Renato de Mello Prado, Antonio Marcio Souza Rocha
Summary: High root absorption of silicon in sugarcane attenuates water deficit-induced damage, but the low relative absorption of Si via leaf spraying compared to root application may also have an immediate antioxidant effect. The research found that foliar spraying of Si has similar or even higher physiological and biochemical effects in relieving short-term water deficit-induced stress compared to root application, indicating that the amount of Si absorbed by the plant is not a major factor in inducing an antioxidant defence response.
JOURNAL OF AGRONOMY AND CROP SCIENCE
(2022)
Article
Plant Sciences
Marcia Masson Mendes dos Santos, Gilmara Pereira da Silva, Renato de Mello Prado, Jose Sidnaldo Pinsetta Junior, Ben-Hur Mattiuz, Heder Braun
Summary: Leaf spraying of silicon from different sources and concentrations can significantly affect the quality of tomato fruits, with the highest increase in ascorbic acid, titratable acidity, and fruit firmness observed with 0.4 g L-1 silicon from the monosilicic acid source.
JOURNAL OF PLANT NUTRITION
(2022)
Article
Horticulture
Victor D'Amico-Damiao, Rafael Ferreira Barreto, Luis Felipe de Oliveira Garcia, John Silva Porto, Renato de Mello Prado, Rogerio Falleiros Carvalho
Summary: The study revealed the important role of the blue light photoreceptor cry1a in tomato nutrient stress responses, particularly in mediating growth and development of stressed plants through changes in plant growth and oxidative stress, as well as the nutrient contents and efficiencies of transport use.
SCIENTIA HORTICULTURAE
(2022)
Article
Plant Sciences
Ian Lucas de Oliveira Rocha, Renato de Mello Prado, Kamilla Silva Oliveira, Dalila Lopes da Silva, Cassio Hamilton Abreu-Junior
Summary: This study evaluated the effects of manganese and silicon added to the foliar spray solution on the physiological aspects, productivity, and protein content of manganese-deficient soybean crops. The results showed that the optimal concentrations of manganese and silicon improved the growth and yield of soybean crops.
JOURNAL OF SOIL SCIENCE AND PLANT NUTRITION
(2022)
Article
Agriculture, Multidisciplinary
Joanderson Marques Silva, Gabriel Barbosa da Silva Junior, Aurenivia Bonifacio, Alexson Filgueiras Dutra, Renato de Mello Prado, Francisco de Alcantara Neto, Alan Mario Zuffo, Rafael Silva Melo, Tassyla Lohanne de Sousa Pereira, Ricardo Silva de Sousa
Summary: This study evaluated the role of salicylic acid (SA) in alleviating water stress in watermelon seedlings at a morphophysiological and biochemical level. The results showed that SA promotes the accumulation of organic solutes and reduces electrolyte leakage, supporting plant growth and metabolism under water deficit conditions.
ANNALS OF APPLIED BIOLOGY
(2023)
Article
Plant Sciences
Gelza Carliane Marques Teixeira, Renato de Mello Prado, Antonio Marcio Souza Rocha, Jose Lucas Farias da Silva, Luis Felipe Lata-Tenesaca, Marcos Altomani Neves Dias
Summary: The treatment of seeds with Mo, accompanied by other elements such as Ni and Co, as well as micronutrients Cu, Mn, and Zn, has been found to be important. The choice of accompanying elements can affect the optimal and toxic doses of Mo. This study investigated the optimal and toxic doses of Mo in the presence of Cu, Mn, and Zn compared to Co and Ni for soybean seed treatment.
JOURNAL OF PLANT NUTRITION
(2023)
Article
Plant Sciences
Gilmar da Silveira Sousa Junior, Alexander Calero Hurtado, Jonas Pereira de Souza Junior, Renato de Mello Prado, Marisa de Cassia Piccolo, Durvalina Maria Mathias Dos Santos
Summary: This study investigates the protective role of silicon (Si) on growth performance, nutrient homeostasis, and C:N:P stoichiometric of sugarcane seedlings under aluminum (Al) stress in hydroponic conditions. The findings suggest that Si supplementation can reverse the adverse effects of Al stress on sugarcane growth, modify nutrient balance, and have varying effects on different plant organs.
JOURNAL OF SOIL SCIENCE AND PLANT NUTRITION
(2022)
Article
Agronomy
Kolima Pena Calzada, Dilier Olivera Viciedo, Eduardo Habermann, Alexander Calero Hurtado, Priscila Lupino Gratao, Renato De Mello Prado, Luis Felipe Lata-Tenesaca, Carlos Alberto Martinez, Gabriela Eugenia Ajila Celi, Juan Carlos Rodriguez
Summary: This study evaluated the effects of foliar application of amino acid mixtures on salt-stressed soybean plants. The results showed that foliar spraying of amino acids significantly improved the physiological and biochemical traits of soybean plants and promoted growth.
Article
Chemistry, Multidisciplinary
Livia Talita da Silva Carvalho, Renato de Mello Prado, Jose Lucas Farias Da Silva, Patricia Messias Ferreira, Renan Izildo Antonio
Summary: The study found that irrigating with nanosilica can alleviate the physiological damage caused by nitrogen and phosphorus deficiencies in beet plants.
Article
Plant Sciences
Kolima Pena Calzada, Alexander Calero Hurtado, Dilier Olivera Viciedo, Eduardo Habermann, Renato de Mello Prado, Reginaldo de Oliveira, Gabriela Ajila, Luis Felipe Lata Tenesaca, Juan Carlos Rodriguez, Priscila Lupino Gratao
Summary: In this study, the regulatory roles of different vias of silicon (Si) applications on soybean responses to salt stress were investigated. It was found that Si application significantly improved soybean tolerance to salinity stress by reducing Na+ uptake and lipid peroxidation, increasing K+ concentration, K+/Na+ ratio and proline accumulation, upregulating enzymatic antioxidant activity, and promoting plant growth.
JOURNAL OF PLANT GROWTH REGULATION
(2023)
Article
Agriculture, Multidisciplinary
Kolima Pena-Calzada, Dilier Olivera-Viciedo, Alexander Calero-Hurtado, Renato de Mello Prado, Eduardo Habermann, Luis Felipe Lata Tenesaca, Gabriela Ajila, Reginaldo de Oliveira, Juan Carlos Rodriguez, Priscila Lupino Gratao
Summary: This study aimed to evaluate the impact of different strategies of silicon (Si) application on salt stress tolerance of soybean. The results showed that Si application mitigated the harmful effects of salt stress on soybean, particularly when combined with foliar spraying and nutrient solution addition.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Plant Sciences
Jonas Pereira de Souza Jr, Renato de Mello Prado, Cid Naudi Silva Campos, Gilmar da Silveira Sousa Jr, Milton Garcia Costa, Simone de Padua Teixeira, Priscila Lupino Grata
Summary: This study evaluated the effects of silicon (Si) and boron (B) on oxidative stress, biomass production, and antioxidant content of cotton flowers under moderate B deficiency. The application of B, Si, and B + Si significantly reduced the levels of malondialdehyde and increased dry matter production in cotton petals and anthers. B deficiency induced oxidative stress in cotton flowers, while Si activated defense mechanisms and mitigated the effects of oxidative stress.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2023)
Article
Chemistry, Physical
Victor Hugo de Farias Guedes, Renato de Mello Prado, Joaquim Jose Frazao, Kamilla Silva Oliveira, Jairo Osvaldo Cazetta
Summary: Foliar application of silicon can reduce the damage caused by zinc deficiency in sorghum plants, increasing zinc accumulation, photosynthetic pigments, and dry matter content, while decreasing cell leakage.
Article
Chemistry, Physical
Murilo de Melo Peixoto, Rilner Alves Flores, Charlismila Amorim do Couto, Haryel Domingos N. Pacheco, Renato de Mello Prado, Jonas Pereira Souza-Junior, Jose Arnaldo Castro-Netto, Dalva Graciano-Ribeiro
Summary: This study analyzed the effects of silicon (Si) application on sunflower plants. The results showed that Si application had positive effects on CO2 assimilation, N uptake, leaf quantity and quality, and total biomass yield in sunflower plants.