Article
Environmental Sciences
Samantha G. Kuschke, Jeanette Wyneken, Carolyn Cray, Emily Turla, Megan Kinsella, Debra L. Miller
Summary: Fungal diseases are becoming a global health problem for humans, animals, and plants. Sea turtle egg fusariosis (STEF) is an example of a fungal disease that affects sea turtles and is caused by Fusarium solani species complex (FSSC). FSSC fungi have been found in sea turtle nests and are associated with decreased hatching success, as well as skin infections in various animals, including humans. However, the presence of Fusarium spp. and its impact on sea turtles in southeastern Florida beaches have not been studied.
FRONTIERS IN MARINE SCIENCE
(2023)
Article
Plant Sciences
Valentina Librizzi, Antonino Malacrino, Maria Giulia Li Destri Nicosia, Nataly Barger, Tal Luzzatto-Knaan, Sonia Pangallo, Giovanni E. Agosteo, Leonardo Schena
Summary: The use of synthetic chemicals in agriculture has caused severe damage to the environment and human health. This study explores the potential of microorganisms and their metabolites as an alternative strategy for environmentally friendly plant disease control. By screening soil microbial diversity, 22 bacterial strains were isolated and their ability to counteract plant pathogens was tested. The extracts from the three most effective bacterial strains exhibited exceptional biocontrol activity in simulated real-world applications.
Article
Soil Science
Tiantian Zheng, Anja Miltner, Chao Liang, Karolina M. Nowak, Matthias Kastner
Summary: Microbial biomass residues play an important role in biogeochemical cycling, but the mechanism by which they are sequestered in soil organic matter remains elusive. This study revealed that bacterial biomass is predominantly utilized by fungi and stabilized as fungal necromass, contributing to soil organic carbon sequestration. The study also identified three phases in the metabolism of microbial biomass residues, with the final phase focused on C preservation rather than energy production.
SOIL BIOLOGY & BIOCHEMISTRY
(2023)
Article
Engineering, Environmental
Yuqi Wang, Bing Li, Haihong Shang, Ruonan Ma, Yupan Zhu, Xudong Yang, Siyao Ju, Wenbo Zhao, Hao Sun, Jie Zhuang, Zhen Jiao
Summary: This study investigated the effects of cold atmospheric plasma (CAP) on the growth, deoxynivalenol (DON) biosynthesis, and pathogenicity of Fusarium spp. The results showed that CAP effectively inactivated major Fusarium strains by destructing cell membrane, accumulating intracellular ROS, and depolarizing mitochondrial membrane. CAP also inhibited DON biosynthesis and reduced the pathogenicity of F. graminearum on wheat. These findings provide insights into the antifungal and detoxification mechanism of CAP against F. graminearum, promoting its application in controlling fungal growth and mycotoxin production in grains and crops.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Plant Sciences
Muhammad Farooq, Yoon-Hee Jang, Eun-Gyeong Kim, Jae-Ryoung Park, Gyu-Hyeon Eom, Dan-Dan Zhao, Kyung-Min Kim
Summary: Amino acids are crucial for plant species, such as rice, as they serve as the fundamental units of protein building blocks. This study aimed to investigate the amino acid profiles of four rice genotypes under NaCl, CaCl2, and MgCl2 stress. The results showed that the content of essential and non-essential amino acids significantly increased in cultivar Cheongcheong under NaCl and MgCl2 application, while total amino acid content increased in cultivar Nagdong under all three salt types. Salt-sensitive cultivar IR28 and salt-tolerant Pokkali exhibited lower levels of total amino acid content under different salt stress conditions. The findings suggest that the amino acid profile of each rice cultivar is influenced by its origin, immune level, and genetic makeup.
Article
Plant Sciences
Yawen Yue, Shuai Zhou, Chilu Cheng, Liming Teng, Jingsong Zhang, Baokai Cui, Wei Han, Yucheng Dai, Na Feng
Summary: A comprehensive and sensitive method combining ultra-performance liquid chromatography with tandem mass spectrometry was developed for the quantification of characteristic triterpenoids in Ganoderma mycelia. The method was validated and applied to determine the optimum fermentation conditions and investigate the distribution of triterpenoids in different Ganoderma species. The results showed that the method was effective for chemotaxonomy of Ganoderma species and provided a helpful analytical methodology for quality control of Ganoderma triterpenoids.
Article
Horticulture
Joana A. Ribeiro, Andre Albuquerque, Patrick Materatski, Mariana Patanita, Carla M. R. Varanda, Maria do Rosario Felix, Maria Doroteia Campos
Summary: This study assessed the level of Fusarium spp. infection in field tomato samples and evaluated the differential expression of target genes involved in plant-pathogen interactions. The results showed that the level of infection positively influenced the expression of defense-related genes in tomato, providing new insights for sustainable plant disease management.
Review
Biotechnology & Applied Microbiology
Melissa Tiemi Hirozawa, Mario Augusto Ono, Igor Massahiro de Souza Suguiura, Jaqueline Gozzi Bordini, Elisabete Yurie Sataque Ono
Summary: Fungal pathogens have a significant impact on crop production and food safety. While agrochemical application is commonly used to reduce fungal contamination, it can also have negative environmental and health effects. A more environmentally friendly approach is the use of lactic acid bacteria (LAB) and Bacillus spp. for biological control, as these bacteria produce molecules that can affect fungal growth and viability in different plants.
JOURNAL OF APPLIED MICROBIOLOGY
(2022)
Article
Plant Sciences
Peiying Zhao, Shubo Gu, Chao Han, Yaru Lu, Chunyang Ma, Jichun Tian, Jianjie Bi, Zhiying Deng, Qunqing Wang, Qian Xu
Summary: This study used untargeted and targeted metabolomics to analyze the metabolite differences between two wheat varieties after Fusarium graminearum infection, revealing differential amino acid metabolic pathways and contents. Exogenous application of amino acids showed proline and alanine increased wheat resistance to FHB, while cysteine aggravated susceptibility. The optimization metabolite extraction method presented an effective strategy to explore the mechanisms involved in FHB resistance.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Environmental Sciences
Geslaine Rafaela Lemos Goncalves, Pedro Vinicius Melo dos Santos, Maria Lucia Negreiros-Fransozo, Antonio Leao Castilho, Marleen De Troch
Summary: Environmental factors and anthropic actions can impact the fatty acid composition of aquatic organisms, particularly in commercially exploited species like Xiphopenaeus spp. This study compared the fatty acid composition of Xiphopenaeus spp. in two coastal sites in Brazil, finding significant differences between the sites. Water pollution and the presence of mangrove forests were identified as potential factors influencing the fatty acid composition and nutritional value of Xiphopenaeus spp.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Yahui Liu, Tianling Ma, Yi Dong, Chenxin Mao, Jianyan Wu, Chuanqing Zhang
Summary: This study demonstrated the varying inhibitory activity of mefentrifluconazole against different Fusarium species, with the strongest effect observed on F. fujikuroi and the weakest effect on F. solani. All F. fujikuroi isolates causing rice bakanae disease (RBD) were sensitive to mefentrifluconazole regardless of their resistance to other DMIs. Furthermore, pre-treatment with mefentrifluconazole 12 hours before inoculation showed better protective efficacy on rice seedlings compared to post-inoculation treatment.
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Irina P. P. Filippova, Olesia N. N. Makhutova, Valeriya E. E. Guseynova, Michail I. I. Gladyshev
Summary: The composition of fatty acids (FAs) in gametophyte samples of 20 Siberian bryophyte species from four orders of mosses and four orders of liverworts collected in relatively cold months was analyzed. The study found 37 FAs, including mono-, polyunsaturated, and rare FAs. Acetylenic FAs were found in all examined species of the Bryales and Dicranales orders. Multivariate discriminant analysis showed that FA composition is related to the taxonomic status of species. Several individual FAs were identified as chemotaxonomic markers at the level of bryophyte orders.
Article
Food Science & Technology
Yijia Deng, Rundong Wang, Yuhao Zhang, Jianrong Li, Ravi Gooneratne
Summary: Free amino acids formed in fermented meat products are crucial for the survival and metabolism of contaminating fungi, and their regulation is mainly controlled by the TORC1-Tap42 signaling pathway. This study investigated the effect of 18 amino acids on the growth, sporulation, toxin synthesis, and gene expression of Fusarium oxysporum. The results showed that certain amino acids positively regulated Fo17 growth and sporulation, while others significantly inhibited growth, not regulated by Tap42. This study contributes to our understanding of amino acid regulation in fermented foods and provides insights into controlling fungal contamination.
Article
Immunology
Joy Ogbechi, Helen L. Wright, Stefan Balint, Louise M. Topping, Zec Kristina, Yi-Shu Huang, Eirini Pantazi, Maarten Swart, Dylan Windell, Eros Marin, Michael F. Wempe, Hitoshi Endou, Andrew M. Thomas, Andrew Filer, Trevor W. Stone, Alexander J. Clarke, Michael L. Dustin, Richard O. Williams
Summary: The aim of this study was to evaluate the potential therapeutic target of L-type amino acid transporter 1 (LAT1) in rheumatoid arthritis (RA). The study found that LAT1 expression in the synovial membrane of RA patients was strongly associated with disease activity and inflammation indicators. Deletion of LAT1 in mouse CD4+ T cells inhibited the development of arthritis and prevented the differentiation of inflammatory T cell subsets. Furthermore, a small molecule LAT1 inhibitor showed promising results in treating experimental arthritis in mice. In conclusion, LAT1 plays a critical role in the activation of pathogenic T cell subsets in RA and represents a promising therapeutic target.
JOURNAL OF AUTOIMMUNITY
(2023)
Article
Biochemistry & Molecular Biology
Pei Song, Wubei Dong
Summary: This study identified an antifungal gene, Mt1, from Bacillus subtilis 330-2, which significantly reduced the pathogenicity of Fusarium graminearum by inhibiting amino acid metabolism. Transcriptome analysis indicated that the most affected metabolic pathway was branched-chain amino acids (BCAAs). These findings provide new targets for developing strategies to control Fusarium head blight in wheat.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Agricultural Engineering
Neha Srivastava, Rajeev Singh, Manish Srivastava, Asad Syed, Dan Bahadur Pal, Ali H. Bahkali, P. K. Mishra, Vijai Kumar Gupta
Summary: The study utilized mixed fungal consortia for solid state fermentation to enhance cellulase production, and improved the thermal and pH stability of cellulase with NiFe2O4 nanoparticles. The treated cellulase was used for enzymatic hydrolysis of biowaste to biofuels, resulting in significantly higher sugar yield and productivity compared to control.
BIORESOURCE TECHNOLOGY
(2022)
Article
Spectroscopy
Bilal Ahmed, Abdallah M. Elgorban, Ali H. Bahkali, Jintae Lee, Asad Syed
Summary: The study developed a probe for selective and sensitive detection of L-cysteine using gold nanoparticles, showing high accuracy in quantifying Cys from various biological samples even in the presence of other amino acids. The proposed Au NPs sensor exhibited excellent reproducibility and selectivity for Cys detection.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Spectroscopy
S. Kokilavani, Asad Syed, Ajith M. Thomas, Abdallah M. Elgorban, Ali H. Bahkali, Nouf S. S. Zaghloul, Lija L. Raju, S. Sudheer Khan
Summary: In this study, a novel sensing approach was developed for the detection of sulphide ions (S-2) in aqueous media. The nanohybrid was characterized using various techniques to confirm its detection capabilities for S-2 ions. The development of a paper strip probe allowed for rapid onsite monitoring of S-2 ions.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Multidisciplinary
Asad Syed, Marzouq H. Al Saedi, Ali H. Bahkali, Abdallah M. Elgorgan, Mahesh Kharat, Kalpana Pai, John Pichtel, Absar Ahmad
Summary: The study successfully biosynthesized gold sulfide nanoparticles (Au2S NPs) using the fungus Humicola sp. and characterized their properties, demonstrating potential applications in anti-leishmanial activity and low cytotoxicity towards normal and cancer cell lines.
GREEN CHEMISTRY LETTERS AND REVIEWS
(2022)
Article
Agricultural Engineering
Dan Bahadur Pal, Amit Kumar Tiwari, Akbar Mohammad, Nirupama Prasad, Neha Srivastava, K. R. Srivastava, Rajeev Singh, Taeho Yoon, Asad Syed, Ali H. Bahkali, Vijai Kumar Gupta
Summary: The study investigates the biofuel potential of rice straw waste biomass materials, and tests its biogas potential under co-digestion mode.
BIORESOURCE TECHNOLOGY
(2022)
Article
Green & Sustainable Science & Technology
Khadim Dawar, Zeeshan Khalil, Ishaq Ahmad Mian, Bushra Khan, Shamsher Ali, Ashfaq Ahmad Rahi, Muhammad Saeed Tahir, Niaz Ahmed, Shah Fahad, Subhan Danish, Asad Syed, Ali H. Bahkali, Rahul Datta
Summary: The study investigated the effects of the optimal application ratio of FYM and SSP on wheat growth and yield, with the results showing that the application of 50% FYM and 50% SSP significantly improved wheat growth and yield, with the potential to enhance nutrient concentration. Further research is needed to fine-tune the synchronization of FYM and SSP for maximum wheat yield.
Article
Nanoscience & Nanotechnology
Abobakr Almansob, Ali H. Bahkali, Ahmed Albarrag, Mohammad Alshomrani, Abdulwahab Binjomah, Waleed A. Hailan, Fuad Ameen
Summary: Drug resistance to antifungal medicines in filamentous fungus is a major problem in biomedical applications, and an effective strategy is needed to treat opportunistic fungal infections. In this study, silver nanoparticles (AgNPs) were prepared using an aqueous extract of Mentha piperita and their antifungal activity against Aspergillus species was investigated. The structural properties of AgNPs were characterized using various techniques, and it was found that AgNPs exhibited a single-phase fcc structure. The antifungal efficacy of AgNPs was determined using disc and broth microdilution methods, and it was found to be highly successful in inhibiting the growth of all tested fungi. The study also revealed that AgNPs had an impact on the enzymatic activity of A. fumigatus.
APPLIED NANOSCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Nadia Arif, Zahid Shafiq, Khalid Mahmood, Muhammad Rafiq, Sadia Naz, Sohail Anjum Shahzad, Umar Farooq, Ali H. Bahkali, Abdallah M. Elgorban, Muhammad Yaqub, Ahmed El-Gokha
Summary: This study focuses on the search for novel heterocyclic compounds with a natural product skeleton as potent enzyme inhibitors. A simple and facile strategy was designed to synthesize a series of coumarin-based compounds, which were then screened and characterized for their inhibition potency. Several compounds showed strong inhibitory activity against the target enzymes, indicating their potential for drug development.
Correction
Health Care Sciences & Services
Ganesh Dattatraya Saratale, Han-Seung Shin, Surendra Krushna Shinde, Dae-Young Kim, Rijuta Ganesh Saratale, Avinash Ashok Kadam, Manu Kumar, Ali Hassan Bahkali, Asad Syed, Gajanan Sampatrao Ghodake
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Plant Sciences
Mohamed A. Abdel-Wahab, E. B. Gareth Jones, Abdallah M. Elgorban, Ali H. Bahkali
Summary: A new marine fungal species, Torpedospora yanbuensis, was discovered in decaying mangrove wood collected in Saudi Arabia. The new species is characterized by its apricot-colored ascomatal venter, hyaline long neck, deciduous outer peridial layer, and thick-walled asci with apical thickening plate and 1-3 septate ascospores with deciduous polar appendages.
Article
Biotechnology & Applied Microbiology
Rasheed Akbar, Imtiaz Ali Khan, Brekhna Faheem, Rashid Azad, Maid Zaman, Rubab Altaf, Amjad Usman, Muhammad Fawad, Abid Farid, Ahmad Ur Rahman Saljoqi, Asad Syed, Ali H. Bahkali, Abdallah M. Elgorban, Jawad Ali Shah, Abdul Qayyum
Summary: This study investigated the repellency potential of five botanicals against Callosbruchus maculatus in Haripur, Pakistan. The results showed that Azadirachta indica and Melia azedarach can be used for the management of C. maculatus and these plant species might be helpful in the production of new biopesticides.
BIOMED RESEARCH INTERNATIONAL
(2022)
Article
Chemistry, Multidisciplinary
Faria Shakeel, Muhammad Waseem Fazal, Anam Zulfiqar, Farhan Zafar, Naeem Akhtar, Arsalan Ahmed, Hafiz Badaruddin Ahmad, Safeer Ahmed, Asad Syed, Ali H. Bahkali, Muhammad Abdullah, Zahid Shafiq
Summary: In this study, a novel N-rich carbon-coated Au nanoparticles (NC@Au-NPs) were fabricated and their catalytic efficacy and shelf life were boosted by applying a mixture of polydopamine (PDA) and benzimidazolium-1-acetate ionic liquid (IL) as a sandwich between the working electrode surface and the designed nanohybrid NC@Au-NPs as a redox mediator. The results showed that the designed NC@Au/PDA-IL/GPE exhibited excellent sensitivity, selectivity, and reproducibility.
Article
Chemistry, Multidisciplinary
Tahira Saleem, Samra Khan, Muhammad Yaqub, Muhammad Khalid, Muhammad Islam, Muhammad Yousaf Ur Rehman, Muhammad Rashid, Iqra Shafiq, Ataualpa A. C. Braga, Asad Syed, Ali H. Bahkali, John F. Trant, Zahid Shafiq
Summary: In this study, quinoline-based chemosensors were synthesized and their interaction with various ions was tested using multiple experimental methods. Computational analysis was also conducted to investigate their chemical behavior in a three-dimensional setting. The findings demonstrate that these chemosensors are viable for optimizing sensors for fluoride ions.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Environmental Sciences
Mohammad Shahid, Mohammad Tarique Zeyad, Asad Syed, Udai B. Singh, Abdullah Mohamed, Ali H. Bahkali, Abdallah M. Elgorban, John Pichtel
Summary: Endophytic bacteria can be used as an alternative to chemical fertilizers and pesticides to improve plant productivity and enhance defense mechanisms against various stresses. In this study, the endophytic isolate BPR-9, identified as Priestia aryabhattai, showed high tolerance to salt, drought, and heavy metal stresses, and exhibited positive effects on crop growth promotion and inhibition of fungal pathogens. Wheat seedlings inoculated with P. aryabhattai showed superior growth under high salt conditions. These findings suggest that endophytic P. aryabhattai strains have the potential to be used as multi-stress reducers and crop growth promoters in important agronomic crops.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Nanoscience & Nanotechnology
Helal F. Al-Harthi, Abu Baker, Abdallah M. Elgorban, Ali H. Bahkali, Ayaz Mukarram Shaikh, Bela Kovacs, Mohd Sajid Khan, Asad Syed
Summary: In this study, a novel fungus Alternaria sp. was isolated and characterized from the vicinity of medicinal plants, and its extracted proteins were used to synthesize highly biocompatible zinc nanoparticles. The synthesized particles were characterized using various physical techniques and were found to possess regular crystallinity and antibacterial and anticancer activities.
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
(2022)
