Journal
JOURNAL OF SAUDI CHEMICAL SOCIETY
Volume 14, Issue 1, Pages 61-68Publisher
ELSEVIER
DOI: 10.1016/j.jscs.2009.12.010
Keywords
5-Aminotetrazole; Tetrazolopyrimidine; Formyl salt; 6-Aminothiouracil; 3H-pyrimido[1,6-a]-pyrimidine
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An easy and efficient route for the synthesis of some tetrazolo[1,5-a]-, pyrazolo[1,5-a]-and pyrimido[1,6-a] pyrimidine derivatives was described through the reaction of sodium salts of formyl ketones with 5-aminotetrazole, 5-aminopyrazole derivatives and 6-aminothiouracil, respectively. The antimicrobial screening of some derivatives of the prepared compounds has been achieved, and it exhibited a moderate activity against the tested microorganisms. (C) 2009 King Saud University. All rights reserved.
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