Article
Geriatrics & Gerontology
Suzanne McIlroy, Edward Walsh, Christina Sothinathan, Elizabeth Stovold, Daniel Norwitz, Sam Norton, John Weinman, Lindsay Bearne
Summary: The study found a strong positive correlation between preoperative walking capacity and postoperative walking capacity. However, spondylolisthesis and the severity of stenosis were not associated with postoperative walking capacity. Further research is needed on mutable prognostic factors to optimize surgical outcomes.
Article
Medicine, General & Internal
Hideaki Nakajima, Kazuya Honjoh, Shuji Watanabe, Akihiko Matsumine
Summary: Lumbar spinal canal stenosis and diffuse idiopathic skeletal hyperostosis tend to develop in the elderly and may result in the need for lumbar surgery. However, diffuse idiopathic skeletal hyperostosis may be a risk factor for poor clinical outcomes following lumbar decompression surgery, especially in patients with diffuse idiopathic skeletal hyperostosis extending to the lumbar segment. This study aimed to identify prognostic factors of lumbar spinal canal stenosis with diffuse idiopathic skeletal hyperostosis and propose a surgical management approach to improve clinical outcomes.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Multidisciplinary Sciences
Baasanjav Uranbileg, Nobuko Ito, Makoto Kurano, Kuniyuki Kano, Kanji Uchida, Masahiko Sumitani, Junken Aoki, Yutaka Yatomi
Summary: The study indicated a potential link between elevated levels of LPC and LPA in cerebrospinal fluid and lumbar spinal canal stenosis. The use of an ATX inhibitor in a compression of DRG model showed promising results in alleviating pain symptoms and reducing populations of microglia and astrocytes in the spinal dorsal horn.
SCIENTIFIC REPORTS
(2021)
Article
Clinical Neurology
Satoshi Ujigo, Naosuke Kamei, Kiyotaka Yamada, Toshio Nakamae, Hideaki Imada, Nobuo Adachi, Yoshinori Fujimoto
Summary: The study aimed to determine the relationship between postural sway and the severity of lumbar spinal canal stenosis as well as the effect on postoperative improvement. Stabilometry was performed on 52 patients who underwent decompression surgery for lumbar spinal canal stenosis. The results showed that the severity of canal stenosis affects postural sway, but it can be improved after surgery.
EUROPEAN SPINE JOURNAL
(2023)
Article
Geriatrics & Gerontology
Sota Nagai, Risa Inagaki, Takehiro Michikawa, Soya Kawabata, Kaori Ito, Kurenai Hachiya, Hiroki Takeda, Daiki Ikeda, Shinjiro Kaneko, Shigeki Yamada, Nobuyuki Fujita
Summary: This study aimed to review polypharmacy in elderly patients with lumbar spinal canal stenosis and examine how surgical treatment reduces polypharmacy. The results showed that the number of drugs postoperatively was significantly less than preoperatively, especially for pain relief and digestive diseases. Multivariable analysis revealed that a higher score in psychological disorders was associated with a reduction of 3 or more drugs after surgery.
Article
Medicine, General & Internal
Sangbong Ko, Wonkee Choi
Summary: This study investigated the correlation between preoperative SF-36 Mental Component Score (MCS) and long-term prognosis after decompression surgery for degenerative lumbar spinal stenosis (DLSS). The results showed a significant negative correlation between preoperative MCS and pain index as well as spinal functional improvement after surgery.
Article
Medicine, General & Internal
Takaya Imai, Sota Nagai, Takehiro Michikawa, Risa Inagaki, Soya Kawabata, Kaori Ito, Kurenai Hachiya, Hiroki Takeda, Daiki Ikeda, Shigeki Yamada, Nobuyuki Fujita, Shinjiro Kaneko
Summary: Treatment for lumbar spinal canal stenosis (LSCS) can be conservative or surgical. This study aimed to examine the impact of lumbar surgery on pharmacological treatment for patients with LSCS. The results showed a significant decrease in LSCS medications after lumbar surgery, but around 15% of the participants experienced an increase in medication use.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Clinical Neurology
Azim N. Laiwalla, Anshul Ratnaparkhi, David Zarrin, Kirstin Cook, Ien Li, Bayard Wilson, T. J. Florence, Bryan Yoo, Banafsheh Salehi, Bilwaj Gaonkar, Joel Beckett, Luke Macyszyn
Summary: This study demonstrated that machine learning algorithms can accurately segment lumbar spinal canals in patients with LS, with automatic delineations comparable to expert-generated segmentations in terms of both quality and quantity.
WORLD NEUROSURGERY
(2023)
Article
Clinical Neurology
Suzanne McIlroy, Feroz Jadhakhan, David Bell, Alison Rushton
Summary: This study found that older age, obesity, greater pre-operative pain and disability, and lower quality of life are associated with an increased risk of poor walking ability post-surgery for lumbar spinal stenosis. On the other hand, greater pre-operative walking distance and higher education were associated with a decreased risk of poor walking ability post-surgery. Patients should be informed of their risk factors and may benefit from rehabilitation to improve their walking and surgical outcomes.
EUROPEAN SPINE JOURNAL
(2021)
Article
Oncology
Jing Wang, Xiang-zhi Ni, Ming-lei Yang, Xing Huang, Shu-ming Hou, Cheng Peng, Jia-shi Cao, Tie-Long Liu
Summary: This study comprehensively analyzed the demographic features, clinicopathologic characteristics and prognosis factors of spinal osteosarcoma using the SEER database. The results showed that male gender, high tumor grade, regional and metastasis stage, as well as radiotherapy, were independent predictors of poor survival in spinal osteosarcoma patients. The clinical treatment of spinal osteosarcoma still faces serious challenges.
FRONTIERS IN ONCOLOGY
(2023)
Article
Engineering, Electrical & Electronic
Sinan Altun, Ahmet Alkan
Summary: Lumbar spinal stenosis (LSS) is a major cause of chronic low back pain. Rapid diagnosis and early treatment of LSS significantly impact quality of life. Machine learning, specifically deep learning, has shown high success rates in processing MRI images. This study proposes a 3D automatic segmentation model for diagnosing LSS using T2 sequence lumbar MRI images. The results show that the proposed model can accurately segment different regions related to LSS, leading to the potential development of a computer-aided diagnosis system.
INTERNATIONAL JOURNAL OF IMAGING SYSTEMS AND TECHNOLOGY
(2023)
Article
Orthopedics
Jun Yang, Zhiyun Feng, Nian Chen, Zhenhua Hong, Yongyu Zheng, Jiang Yang, Tingjie Zhou, Xin Yao, Taifeng Xu, Linting Zhang
Summary: The study found that the sedimentation of lumbar spine nerve roots is influenced by the direction of gravity, and positive sedimentation sign may be associated with lumbar pathology.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Clinical Neurology
Zhuanghui Wang, Yuluo Rong, Pengyu Tang, Wu Ye, Chengyue Ji, Jiaxing Wang, Xuhui Ge, Wei Liu, Qingqing Li, Weihua Cai
Summary: The study revealed that 61.4% of lumbar spinal stenosis (LSS) patients also have asymptomatic spondylotic cervical spinal stenosis (ASCSS), with lumbar lordosis angle (LLA) >35.85 degrees and dural sac cross-sectional area (DCSA) <84.50 mm^2 being risk factors for ASCSS development. Additionally, the cervical stenosis index showed a significant positive correlation with the lumbar stenosis index.
WORLD NEUROSURGERY
(2021)
Article
Orthopedics
Ning Fan, Shuo Yuan, Peng Du, Qichao Wu, Tianyi Wang, Aobo Wang, Jian Li, Xiaochuan Kong, Wenyi Zhu, Lei Zang
Summary: Complications of PETD in treating LSS include rLSS, persistent lumbosacral or lower extremity pain, dural tear, incomplete decompression, surgical site infection, epidural hematoma, and intraoperative posterior neck pain. Furthermore, older age, severe grade of surgical-level disc degeneration, and more disc degeneration levels significantly increase the incidence of complications.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Review
Oncology
Yue Cao, Yu-Bo Wang, Yang Bai, Xuan-yu Tan, Cheng-yuan Ma, Yong Chen, Hong-quan Yu, Hai-Yang Xu, Gang Zhao
Summary: Primary sporadic intradural MPNST in the spinal canal is a rare malignant tumor with challenging diagnosis and treatment. This systematic review aims to reduce misdiagnosis and improve prognosis by reviewing the literature. The study included 55 cases of spinal intradural primary sporadic MPNSTs, with the most common clinical manifestations being pain and motor disturbance. Radiologically, all tumors showed significant enhancement. The prognosis of the disease is unclear, with high recurrence and mortality rates even after surgical and adjuvant treatment.
FRONTIERS IN ONCOLOGY
(2022)