Article
Cardiac & Cardiovascular Systems
Shin-Yi Lin, Yu-Chen Chang, Fang-Ju Lin, Sung-Chun Tang, Yaa-Hui Dong, Chi-Chuan Wang
Summary: This study investigated the effectiveness and safety of continuing or restarting antithrombotic agents in patients with atrial fibrillation after intracranial hemorrhage. The results showed that oral anticoagulants reduced the risk of ischemic stroke without increasing the risk of subsequent intracerebral hemorrhage. On the other hand, antiplatelet agents increased the risk of intracerebral hemorrhage. Neither anticoagulants nor antiplatelet agents reduced the risk of all-cause mortality. Non-vitamin K antagonist oral anticoagulants showed similar effectiveness in reducing ischemic stroke risk compared to warfarin, but had better survival benefits.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Cardiac & Cardiovascular Systems
So-Ryoung Lee, Jin-Hyung Jung, Eue-Keun Choi, Seung-Woo Lee, Soonil Kwon, Ji-Suck Park, Jeehoon Kang, Kyung-Do Han, Kyung Woo Park, Seil Oh, Gregory Y. H. Lip
Summary: This study compared the net clinical benefit of different antithrombotic treatment options in patients with atrial fibrillation and stable coronary artery disease who underwent percutaneous coronary intervention. The results showed that oral anticoagulant monotherapy may be a comparable choice for these patients, and in patients with stable coronary artery disease more than 3 years after PCI, OAC monotherapy was associated with less major bleeding and a positive net clinical benefit.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Review
Clinical Neurology
Elena Ivany, Leona A. Ritchie, Gregory Y. H. Lip, Robyn R. Lotto, David J. Werring, Deirdre A. Lane
Summary: In nontraumatic ICrH survivors with atrial fibrillation, OAC therapy is associated with a reduced risk of thromboembolic events and all-cause mortality without significantly increasing risk of recurrent ICrH.
Article
Cardiac & Cardiovascular Systems
Kotaro Nochioka, Satoshi Yasuda, Yasuhiko Sakata, Takashi Shiroto, Hideka Hayashi, Jun Takahashi, Hiroyuki Takahama, Satoshi Miyata, Hiroaki Shimokawa
Summary: This study found that chronic heart failure patients with a history of cancer and atrial fibrillation have a higher risk for stroke, systemic thrombosis, and major bleeding, especially in the elderly and those with ischemic heart disease. However, a considerable number of patients did not receive anticoagulant therapy.
Article
Pharmacology & Pharmacy
Sijie Chang, Wenlin Xu, Shuyi Wu, Lien Desteghe, Feilong Zhang, Jinhua Zhang
Summary: This study translated the Jessa Atrial fibrillation Knowledge Questionnaire (JAKQ) into Chinese and evaluated its reliability and validity. The results showed that the Chinese version of JAKQ has good reliability and validity and can be used to guide educational activities to improve the effectiveness and safety of atrial fibrillation oral anticoagulation (OAC) treatment. Chinese patients with atrial fibrillation have insufficient knowledge about atrial fibrillation and OAC. Lower JAKQ scores are associated with bleeding, indicating the need for targeted education.
FRONTIERS IN PHARMACOLOGY
(2023)
Review
Pharmacology & Pharmacy
Teng J. Peng, Catherine Viscoli, Pooja Khatri, Stacey Q. Wolfe, Nirav R. Bhatt, Tarun Girotra, Hooman Kamel, Kevin N. Sheth
Summary: Spontaneous intracerebral hemorrhage (ICH) is a type of stroke and survivors are at risk for recurrent hemorrhagic and ischemic cerebrovascular events, especially those with atrial fibrillation (AF). The decision to initiate or resume versus withhold anticoagulation in survivors of ICH with AF is a conundrum in the field of vascular neurology, neurosurgery, and cardiology.
Article
Pharmacology & Pharmacy
Han-Hsin Chueh, Shih-Tsung Huang, Shang-Hung Chang, Shin-Yi Lin, Fei-Yuan Hsiao
Summary: This study compared the risks of different antithrombotic regimens in Asian atrial fibrillation patients with stent insertions. The results demonstrated that dual antiplatelet therapy (DAPT), double therapy, and triple therapy had similar effectiveness, but triple therapy had a significantly higher risk of major bleeding.
CLINICAL PHARMACOLOGY & THERAPEUTICS
(2022)
Article
Cardiac & Cardiovascular Systems
James Freeman, Angela Y. Higgins, Yongfei Wang, Chengan Du, Daniel J. Friedman, Usama A. Daimee, Karl E. Minges, Lucy Pereira, Andrew M. Goldsweig, Matthew J. Price, Vivek Y. Reddy, Douglas Gibson, Shephal K. Doshi, Paul D. Varosy, Frederick A. Masoudi, Jeptha P. Curtis
Summary: This study evaluated the postprocedure care patterns and compared the risk of adverse events for different discharge antithrombotic strategies after left atrial appendage occlusion (LAAO) with the Watchman device. The study found that practitioners rarely followed the recommended postprocedure treatment protocols and that discharge on warfarin or direct oral anticoagulants (DOACs) without aspirin was associated with a lower risk of adverse outcomes.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Masaharu Akao, Hisashi Ogawa, Nobutoyo Masunaga, Kimihito Minami, Kenjiro Ishigami, Syuhei Ikeda, Kosuke Doi, Yasuhiro Hamatani, Takashi Yoshizawa, Yuya Ide, Akiko Fujino, Mitsuru Ishii, Moritake Iguchi, Hiromichi Wada, Koji Hasegawa, Hikari Tsuji, Masahiro Esato, Mitsuru Abe
Summary: Over the past 10 years, there has been a major transition in antithrombotic therapy and a decline in the incidence of adverse events in AF patients.
CIRCULATION JOURNAL
(2022)
Article
Cardiac & Cardiovascular Systems
Yangxun Wu, Haiping Liu, Liu'an Qin, Yuyan Wang, Shizhao Zhang, Ziqian Wang, Yuting Zou, Tong Yin
Summary: Antithrombotic therapy with oral anticoagulants (OACs) in elderly patients with ACS and AF was associated with a lower risk of ischemic events without an increase in bleeding events.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Medicine, General & Internal
Woldesellassie M. Bezabhe, Luke R. Bereznicki, Jan Radford, Barbara C. Wimmer, Colin Curtain, Mohammed S. Salahudeen, Gregory M. Peterson
Summary: Factors influencing the initiation and choice of oral anticoagulants in Australian general practice patients newly diagnosed with atrial fibrillation were investigated. The study found a marked increase in the proportion of newly diagnosed AF patients initiated on OAC, especially following the introduction of DOACs. The use of DOACs also increased significantly, with the majority of OAC initiations transitioning to DOACs by the end of the study period.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
(2021)
Article
Hematology
Antonella Tufano
Summary: The management of atrial fibrillation (AF) in cancer patients is challenging, and individualized anticoagulation therapy should be tailored. Multidisciplinary collaboration and periodic reassessment are necessary.
THROMBOSIS RESEARCH
(2022)
Article
Cardiac & Cardiovascular Systems
Joris J. Komen, Tomas Forslund, Aukje K. Mantel-Teeuwisse, Olaf H. Klungel, Mia von Euler, Frieder Braunschweig, Hakan Wallen, Paul Hjemdahl
Summary: This study analyzed 90-day mortality in atrial fibrillation (AF) patients after a stroke or a severe bleed, and found that NOAC treatment was associated with lower mortality rates, while warfarin may lead to higher mortality rates after intracranial hemorrhage.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY
(2021)
Article
Multidisciplinary Sciences
Hyungdon Kook, Hee-Dong Kim, Jaemin Shim, Young-Hoon Kim, Jung-Sun Kim, Hui-Nam Pak, Hyun-Jong Lee, Rak-Kyeong Choi, Woong-Chol Kang, Eun-Seok Shin, Jai-Wun Park, Cheol Woong Yu, Do-Sun Lim
Summary: This study compared patients with AF undergoing DES implantation treated with LAAO and DAPT with those on MAT. The LAAO group showed better outcomes in preventing CVA and major bleeding compared to the MAT group. Further large-scale trials are needed to compare with NOACs.
Article
Clinical Neurology
Oh Young Bang, Siin Kim, Young Keun On, Myung-Yong Lee, Sung-Won Jang, Seongwook Han, Jaeyun Ryu, Seongsik Kang, Hae Sun Suh, Young-Hoon Kim
Summary: NOACs have been proven to be alternative medications for preventing stroke in patients with non-valvular atrial fibrillation. However, the use of antiplatelet agents, warfarin, and NOACs in clinical practice is influenced by patient factors.
FRONTIERS IN NEUROLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Dong Geum Shin, Minwoo Lee, Jinhee Ahn, Sang-Jin Han, Hong Euy Lim
Summary: This study evaluated the procedural safety of a single bolus administration of heparin without ACT measurement during cryoballoon ablation in patients with uninterrupted NOAC intake.
JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Jae-Sun Uhm, Kyu-Yong Ko, Chi Young Shim, Je-Wook Park, Minkwan Kim, Sung A. Bae, In Hyun Jung, In-Soo Kim, Jong Youn Kim, Eui-Young Choi, Won Jeong Son, Yun Ho Roh, Hee Tae Yu, Tae-Hoon Kim, Geu-Ru Hong, Boyoung Joung, Hui-Nam Pak, Moon-Hyoung Lee
Summary: This study aimed to investigate the relationship between premature ventricular complexes (PVCs) and right ventricular (RV) dysfunction, and the impact of radiofrequency catheter ablation (RFCA) on RV function. The results showed that frequent PVCs are associated with RV dysfunction and successful RFCA can reverse RV dysfunction.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2023)
Article
Medicine, General & Internal
Hanjin Park, Hee Tae Yu, Tae-Hoon Kim, Junbeom Park, Jin-Kyu Park, Ki-Woon Kang, Jaemin Shim, Jin-Bae Kim, Jun Kim, Eue-Keun Choi, Hyung Wook Park, Young Soo Lee, Boyoung Joung
Summary: This study compared the safety and efficacy of DOAC with warfarin or no OAC in patients with advanced CKD or ESRD on dialysis who have atrial fibrillation. It found that DOAC was associated with a lower risk of bleeding and adverse clinical outcomes compared to warfarin or no OAC.
YONSEI MEDICAL JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Sung Hwa Choi, Hee Tae Yu, Daehoon Kim, Je-Wook Park, Tae-Hoon Kim, Jae-Sun Uhm, Boyoung Joung, Moon-Hyoung Lee, Chun Hwang, Hui-Nam Pak
Summary: This study aims to explore the mechanism of long-term recurrence in patients with atrial fibrillation (AF). The findings suggest that patients with a later recurrence of AF have smaller left atrial volume, lower left atrial voltage, and more extra-pulmonary vein triggers during the repeat procedure.
Article
Cardiac & Cardiovascular Systems
Jinhee Ahn, Dong Geum Shin, Sang-Jin Han, Hong Euy Lim
Summary: The aim of this study was to investigate the safety and efficacy of fluoroless cryoballoon ablation for atrial fibrillation under intracardiac echocardiography guidance. The study showed that all patients underwent successful cryoballoon ablation, and the fluoroscopy time and radiation exposure were significantly lower in the fluoroless group. The follow-up results showed similar recurrence rates between the two groups. Therefore, intracardiac echocardiography-guided fluoroless cryoballoon ablation is a feasible strategy for treating atrial fibrillation.
Article
Cardiac & Cardiovascular Systems
Juntae Kim, Dongmin Kim, Eunsun Jang, Daehoon Kim, Seng Chan You, Hee Tae Yu, Myung-Yong Lee, Gregory Lip, Pil-Sung Yang, Boyoung Joung
Summary: The study investigated the association of high-normal blood pressure and impaired fasting glucose with the risk of atrial fibrillation in two cohorts. The findings showed that high-normal blood pressure and impaired fasting glucose were important risk factors for atrial fibrillation in healthy individuals. The risk of new-onset atrial fibrillation significantly increased when high-normal blood pressure and impaired fasting glucose were combined. Lifestyle interventions should be considered to reduce the risk of atrial fibrillation in individuals with high-normal blood pressure and impaired fasting glucose.
Article
Cardiac & Cardiovascular Systems
Ga-In Yu, Tae-Hoon Kim, Hee Tae Yu, Boyoung Joung, Hui-Nam Pak, Moon-Hyoung Lee
Summary: This study evaluated the learning curve for LBBAP using SDL. The results showed that fluoroscopy and procedural times improved with increasing operator experience after the first 24-25 cases. LBBAP is a safe and effective procedure suitable for operators with experience in cardiac pacemaker implantation.
JOURNAL OF INTERVENTIONAL CARDIOLOGY
(2023)
Article
Multidisciplinary Sciences
Sung Hwa Choi, Pil-Sung Yang, Daehoon Kim, Jung-Hoon Sung, Eunsun Jang, Hee Tae Yu, Tae-Hoon Kim, Hui-Nam Pak, Moon-Hyoung Lee, Gregory Y. H. Lip, Boyoung Joung
Summary: Obesity is associated with atrial fibrillation (AF) burden and severity, and studies suggest that AF is more common in white populations compared to Asians. This study analyzed data from the Korean National Health Insurance Service's Health Screening and the U.K. Biobank, and found that obesity is a risk factor for AF in both European and Asian populations.
SCIENTIFIC REPORTS
(2023)
Letter
Cardiac & Cardiovascular Systems
Joongmin Kim, Daehoon Kim, Hee Tae Yu, Tae-Hoon Kim, Boyoung Joung, Moon-Hyoung Lee, Hui-Nam Pak
Summary: This study evaluated the incidence of pulmonary vein stenosis after atrial fibrillation catheter ablation using computed tomography images. The results showed that high-power short-duration ablation may increase the risk of pulmonary vein stenosis.
Article
Cardiac & Cardiovascular Systems
So-Ryoung Lee, Hyoung-Seob Park, Soonil Kwon, Eue-Keun Choi, Seil Oh
Summary: This study aimed to evaluate the efficacy and safety of personalized Ablation Index (AI) strategy based on left atrial wall thickness (LAWT) assessed by cardiac computed tomography (CT) in pulmonary vein isolation (PVI) for atrial fibrillation (AF). The results showed that the personalized AI strategy can reduce acute pulmonary vein reconnection after PVI.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2023)
Article
Medicine, General & Internal
Hanjin Park, Pil-Sung Yang, Jung-Hoon Sung, Moo-Nyun Jin, Eunsun Jang, Hee Tae Yu, Tae-Hoon Kim, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung
Summary: This study investigated the association between the combined effects of physical activity intensity and PM10 and mortality in older adults. The results showed that for participants engaged in moderate or vigorous intensity physical activity, an increase in the proportion of vigorous intensity to total activity sessions was associated with increased mortality risk under high PM10 exposure and decreased risk under low to moderate PM10 exposure. For participants engaged in light or moderate intensity physical activity, an increase in the proportion of moderate intensity to total activity sessions was associated with decreased mortality risk under high and low to moderate PM10 exposure.
MAYO CLINIC PROCEEDINGS
(2023)
Article
Medicine, General & Internal
Ho-Gi Chung, Junbeom Park, Jin-Kyu Park, Ki-Woon Kang, Jaemin Shim, Jin-Bae Kim, Jun Kim, Eue-Keun Choi, Hyung Wook Park, Young Soo Lee, Boyoung Joung
Summary: This study investigated the relationship between rhythm control and cardiovascular outcomes in a contemporary atrial fibrillation (AF) registry. No difference in the risk of cardiovascular or cerebrovascular outcomes was found between the rhythm control and rate control groups. These findings suggest that early rhythm control should be considered to improve patient outcomes.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Tae -Min Rhee, Hyo-Jeong Ahn, Sunhwa Kim, So-Ryoung Lee, Eue-Keun Choi, Seil Oh
Summary: The electro-mechanical coupling index electromechanical window (EMW) can be used to predict fatal ventricular arrhythmias. The study found that EMW has an additive effect in predicting fatal ventricular arrhythmias in high-risk patients with implantable cardioverter-defibrillator (ICD) devices.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2023)
Article
Cardiac & Cardiovascular Systems
Chan Soon Park, Hosu Kim, So-Ryoung Lee, Ji Hyun Lee, Youngjin Cho, Eue-Keun Choi, Il-Young Oh, Seil Oh
Summary: This study aimed to investigate the prognostic value of early recurrence in patients with atrial fibrillation (AF) treated with cryoballoon ablation (CBA). The results showed a significant association between early recurrence and late recurrence, indicating that early recurrence is an independent risk factor for late recurrence. Therefore, further prospective studies are recommended to verify the risks and benefits of early rhythm control in patients with early recurrence.
JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY
(2023)
Article
Endocrinology & Metabolism
So-Ryoung Lee, Jungmin Choi, Eue-Keun Choi, Huijin Lee, Minju Han, Hyo-Jeong Ahn, Soonil Kwon, Seung-Woo Lee, Kyung-Do Han, Seil Oh, Gregory Y. H. Lip
Summary: This observational cohort study evaluated the impact of early rhythm control on patients with T2DM and AF. The results showed that early rhythm control was associated with reduced risks of ischemic stroke, macrovascular and microvascular complications, and all-cause death.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2023)